# PUBLICATIONS

1. **Channelopathies (Olmsted Syndrome)-causing point mutations of TRPV3 disrupt cellular thermal homeostasis in human keratinocytes**, Chattapadhya, A.; Sahu, R. P.; Das, N. K.; Chang, Y. T.; Goswami, C. Life Sci. 2026, 395, 124362. (published on 2026 4 1) [https://doi.org/10.1016/j.lfs.2026.124362](https://doi.org/10.1016/j.lfs.2026.124362)

1. **Bmal1 regulates thermogenic function by modulation of lipolytic and OXPHOS gene expression in male mice brown adipocytes**, Nagata, N.; Sugiyama, R.; Kohno, S.; Yamazaki, T.; Arai, S.; Sasaki, G.; Xu, P.; Morishige, J. I.; Iba, T.; Miyazaki, R.; Takahashi, C.; Chang, Y. T.; Fujiwara, T.; Fujiwara, H.; Ando, H. Endocrinology **2026**, 167(4):bqag023. (published on 2026 3 6) [https://doi.org/10.1210/endocr/bqag023](https://doi.org/10.1210/endocr/bqag023)

1. **Mechanism elucidation of cell-selective fluorescent probes**, Sarkar, S.; Chang, Y. T.* Smart Mol.** 2026**, 4(1): e70025. (published on 2026 3 1) [https://doi.org/10.1002/smo2.70025](https://doi.org/10.1002/smo2.70025)

1. **TRPM8 Regulates Mitochondrial Ca2+-Dynamics, Temperature and Endoplasmic Reticulum-Mitochondrial Contact Points in T Cell**, Acharya, T. K.; Kumar, S.; Rokade, T. P.; Mahapatra, P.; Chang, Y. T.; Goswami, C. J. Cell Mol. Med. **2026**, 30 (3): e71014. (published on 2026 2) [https://doi.org/10.1111/jcmm.71014](https://doi.org/10.1111/jcmm.71014)

1. **Visualization of Lipid Droplets in Living Cells Using (4‐Methoxyphenyl) Ethynyl‐Naphthalimide**, Pham, Q. N. N.; Triet,H. M.; Sukwattanasinitt, M.; Chang, Y. T._; Rashatasakhon, P._ ChemPhotoChem **2026**, 10(2), e202500329. (published on 2026 2) [https://doi.org/10.1002/cptc.202500329](https://doi.org/10.1002/cptc.202500329)

1. **Dual binding and efflux mechanisms involving HMOX2 and ABCB1 regulate the tumor selectivity of a near-infrared theranostic probe**, Ramos, S. C.; Lee, Y. A.; Mun, S. K.; Miyamoto, N.; Sim, H. B.; Lee, J. B.; Han, J. Y.; Wuestefeld, T.; Lek, C. C. J.; Chung, H. S.; Jang, J. H.; Jeong, S. H.* Chang, Y. T.*, Kim, J. J.* Int. J. Biol. Macromol. **2026**, 340, 150157. (published on 2026 1 9)  [https://doi.org/10.1016/j.ijbiomac.2026.150157](https://doi.org/10.1016/j.ijbiomac.2026.150157)

1. **Modulation of cellular and mitochondrial dysfunction by TRPV4 during early stages of Vincristine-induced neurotoxicity in cultured neuronal model**, Das, N. K.; Mohanta, S.; Aswin, T.; Mishra, S.; Acharya, T. K.; Chang, Y. T.; Goswami, C. Neuropharmacology **2026**, 282: 110708 (2026 1 1) [https://doi.org/10.1016/j.neuropharm.2025.110708](https://doi.org/10.1016/j.neuropharm.2025.110708)

1. **From loss of Ca2+-influx to altered organelle temperature and energy failure: A neonatal-lethal TRPV4 mutant (L618P)**, Mishra, S.; Dubey, N. K.; Das, N. K.; Das, B.; Rajalaxmi, S.; Kumar, S.; Acharya, T. K.; Chang, Y. T, Goswami C. Life Sci. **2025**, 383, 124039. (published on 2025 12 15) [https://doi.org/10.1016/j.lfs.2025.124039](https://doi.org/10.1016/j.lfs.2025.124039)

1. **Alteration of Metabolic Activity Regulates Mitochondrial Temperature in Diagnosis in HepG2 Hepatocellular Carcinoma Cells, Gaser**, O. A.; Nasr, M. A.; Hussein, A. E.; Salah, R. A.; Saad, S. M.; Ehab, S.; Aboomar, N. M.; Elmehrath, A. O.; Salah, A.; Chang, Y. T.; Hedrick, M.; Castanedo, L. A. M.; Fahimi, P.; Matta, C. F.; El-Badri, N. Sci. Rep. **2025**, 15(1), 41155. (published on 2025 11 21) [https://doi.org/10.1038/s41598-025-02807-0](https://doi.org/10.1038/s41598-025-02807-0)

1. **Polarity and Viscosity-Sensitive Fluorescent Probe for Lipid Droplet Imaging, Leewongsat**, K.; Pham, Q. N. N.; Namuangruk, S.; Sukwattanasinitt, M.; Chang, Y. T.; Rashatasakhon, P.* ChemPhotoChem **2025**, 9 (11), e202500176. (published on 2025 11 11) [https://doi.org/10.1002/cptc.202500176](https://doi.org/10.1002/cptc.202500176)

1. **Unraveling the mode of action of a neuron-specific fluorescent probe, NeuO: Intracellular phosphorylation through PAK6 kinase**, Kim, B.*; Ko, D.; Kim, S. B.; Kim, S. Kim, M.; Hong, N. K.; Park, S. Y.; Kim, W.; Lee, B. C.; Lee, Y.; Sim, T.; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. **2025**, 64: e2024 (published on 2025 9 8) [http://doi.org/10.1002/anie.202511160](http://doi.org/10.1002/anie.202511160)

![Image](https://upload.cafenono.com/image/slashpageHome/20250828/170019_MHF95Kt7ZQuEfWzV9J?q=80&s=1280x180&t=outside&f=webp)

1. **Interpretation of the Transcriptome-Based Signature of Tumor-Initiating Cells, the Core of Cancer Development, and the Construction of a Machine Learning-Based Classifier**, Jeong, S. H.; Kim, J. J.; Jang, J. H.*; Chang, Y. T.* Cells **2025**, 14 (16): 1255. (published on 2025 8 14)  [https://doi.org/10.3390/cells14161255](https://doi.org/10.3390/cells14161255)

1. **Harnessing Dye-Induced Local Heating in Lipid Membranes: A Path to Near-Infrared Light-Modulated Artificial Synaptic Vesicles**, Sarker, S. R.; Yamazaki, T.; Sou, K.; Takemura, I.; Kurita, Y.; Nomura, K.; Ichimura, M.; Suzuki, T.; Kai, A.; Araki, T.; Hattori, S.; Furuyama, T.; Chang, Y. T.; Kiya, T.; Arai, S. ACS Nano **2025**, 19(31), 28768-28783. (published on 2025 8 12) [https://doi.org/10.1021/acsnano.5c08482](https://doi.org/10.1021/acsnano.5c08482)

1. **Oxaborole-Functionalized Sialylated Glycan Probe for High-Fidelity Fluorescence Imaging of Cancer Tissue**, Ko, K.; Gao, M.; Sarkar, S.; Kwon, H. Y.; Chang, Y. T.* J. Am. Chem. Soc. **2025**, 147(23), 19718-19726. (published on 2025 6 11) [https://doi.org/10.1021/jacs.5c03020](https://doi.org/10.1021/jacs.5c03020)

![Image](https://upload.cafenono.com/image/slashpageHome/20250828/170102_woxzEjKXBDNgsp0ZqI?q=80&s=1280x180&t=outside&f=webp)

1. **Technical note: Flow cytometry assays for the detection, counting and cell sorting of polyphosphate-accumulating bacteria**, Bouquet, C.; Billard, H.; Bidaud, C. C.; Colombet, J.; Chang, Y. T.; Artigas, J.; Batisson1, I.; Benzerara, K.; Skouri-Panet, F.; Duprat, E.; Lehours1, A. C. Biogeosciences **2025**, 22(7), 1729-1744 (published 2025 4 7) [https://bg.copernicus.org/articles/22/1729/2025/](https://bg.copernicus.org/articles/22/1729/2025/)

1. **Label-Free Enrichment of Highly Metastatic Tumor-Initiating Cells up to a Monoclonal State**, Ciaramicoli, L. M.; Kwon, H. Y.; Im, C. Y.; Kim, N.; Oh, Y.; Chang, Y. T.*; Kang, N. Y.* Biomater. Res.** 2025**, 29, 0168. (published on 2025 4 2) [https://doi.org/10.34133/bmr.0168](https://doi.org/10.34133/bmr.0168)

1. **Rewritable wavelength-selective hydrogel actuators grafted with fluorophores**, Koo, H. B.; Yeon, H.; Yoon, Y. B.; Lee, T. J.; Chang, Y. T.; Chang, J. B. Mater. Horiz.** 2025**, 12(7), 2255-2266. (published 2025 3 31) [https://doi.org/10.1039/d4mh01294a](https://doi.org/10.1039/d4mh01294a)

1. **Super-Photostable Organic Dye for Long-Term Live-cell Single Protein Imaging**, Kim, D. H.*; Triet, H. M.; Lee, S. H.; Jazani, S.; Jang, S.; Abedi, S. A. A.; Xiagang, L.; Seo, J.; Ha, T.; Chang, Y. T.*, Ryu, S. H.* Nat. Methods, **[2025](https://doi.org/10.1038/s41592-024-02584-0)**, 22(3), 550-558. (published on 2025 3 22) [https://doi.org/10.1038/s41592-024-02584-0](https://doi.org/10.1038/s41592-024-02584-0)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163236_AuukJ7sWncqUQlA071?q=80&s=1280x180&t=outside&f=webp)

1. **A Non-Invasive, Label-Free Method for Examining Tardigrade Anatomy Using Holotomography**, Hong, M. T.; Lee, G.; Chang, Y. T. Tomography **2025**, 11(3), 34. (published on 2025 3 14) [https://doi.org/10.3390/tomography11030034](https://doi.org/10.3390/tomography11030034)

1. **A Pair of Fluorescent Probes Enabling Precise Diagnosis of Liver Cancer by Complementary Imaging**, Gao, M.; Lee, S. H.; Kwon, H. Y.; Ciaramicoli, L. M.; Jo, E.; Yu, Y. H.; Li, F.; Kim, B.; Hong, K.; Lee, J. S.; Kim, N.; Oh, Y.; Im, C. Y.; Tan, C. S. H.*; Ha, H. H.*; Chang, Y. T.* ACS Cent. Sci. **2025**, 11(1), 76-83. (published on 2025 1 22) [https://doi.org/10.1021/acscentsci.4c01822](https://doi.org/10.1021/acscentsci.4c01822)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163311_3XwCLUjEfWKHvcEzwG?q=80&s=1280x180&t=outside&f=webp)

1. **Atom Efficient Synthesis of Trimethine Cyanines Using Formaldehyde as a Single Carbon Source**, Lee, S. H.; Lee, T. J.; Sarkar, S.; Cho, H.; Pham, Q. N. N.; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. **2025**, 64 (1): e202413121 (published on 2025 1 2) [https://doi.org/10.1002/anie.202413121](https://doi.org/10.1002/anie.202413121)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163336_ejD8uyZHVGkyW7b4Im?q=80&s=1280x180&t=outside&f=webp)

1. **A preclinical and phase I clinical study of ex vivo-expanded amyloid beta-specific human regulatory T cells in Alzheimer’s disease**, Yang, H.; Byun, M. S.; Ha, N. Y.; Yang, J.; Park, S. Y.; Park, J. E.; Yi, D.; Chang, Y. T.; Jung, W. S.; Kim, J. Y.; Kim, J.; Lee, D. Y.; Bae, H. Biomed. Pharmacother. **2024**, 181: 117721. (published on 2024 12 2) [https://doi.org/10.1016/j.biopha.2024.117721](https://doi.org/10.1016/j.biopha.2024.117721)

1. **TRPV4 modulation affects mitochondrial parameters in adipocytes and its inhibition upregulates lipid accumulation**, Kumar, S: Acharya, T. K.; Kumar, S.; Mahapatra, P.; Chang, Y. T.; Goswami, C. Life Sci. **2024**, 358: 123130. (published on 2024 12 1) [https://doi.org/10.1016/j.lfs.2024.123130](https://doi.org/10.1016/j.lfs.2024.123130)

1. **Fluorescence-guided tumor visualization of colorectal cancer using tumor-initiating probe yellow in preclinical models**, Kim, S. Y.; Kim, J.; Kim, H.; Chang, Y. T.; Kwon, H. Y.; Lee, J. L.; Yoon, Y. S.; Kim, C. W.; Hong, S. M.; Shin, J. H.; Hong, S. W.; Hwang, S. W.; Ye, B. D.; Byeon, J. S.; Yang, S. K.; Son, B. H.; Myung, S. J. Sci. Rep. **2024**, 14(1): 26946. (published on 2024 11 6) [https://doi.org/10.1038/s41598-024-76312-1](https://doi.org/10.1038/s41598-024-76312-1)

1. **Hypoxia-inducible factor-1α-deficient adipose-tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein-1**, Kang, G. S.; Kim, Y. E.; Oh, H. R.; Jo, H. J.; Bok, S.; Jeon, Y. K.; Cheon, G. J.; Roh, T. Y.; Chang, Y. T.; Park, D. J.; Ahn, G. O. Lab. Anim. Res. **2024**, 40(1):37. (published on 2024 10 30) [https://doi.org/10.1186/s42826-024-00224-4](https://doi.org/10.1186/s42826-024-00224-4)

1. **Osseointegrative and immunomodulative 3D-Printing Ti6Al4V-based implants embedded with biogenic hydroxyapatite**, Park, S.; Lee, J.; Kim, J. J.; Ji, M.; Cho, E.;Sim, H. B.; Chang, Y. T.; Chung, J. H.; Paik, M. J.; Kim, J.; Hoon, S. Mater. Des. **2024**, 240: 112822. (published on 2024 4 1) [https://doi.org/10.1016/j.matdes.2024.112822](https://doi.org/10.1016/j.matdes.2024.112822)

1. **Reduced dynamicity and increased high-order protein assemblies in dense fibrillar component of the nucleolus under cellular senescence**, Jo, M.; Kim, S.; Park, J.; Chang, Y. T.; Gwon, Y. Redox Biol. **[2024](https://doi.org/10.1016/j.redox.2024.103279)**, 75:103279. (published on 2024 9 1) [https://doi.org/10.1016/j.redox.2024.103279](https://doi.org/10.1016/j.redox.2024.103279)

1. **TRPM8 affects relative “cooling and heating” of subcellular organelles in microglia in a context-dependent manner**, Shikha, D.; Chang, Y. T.; Goswami, C. Int. J. Biochem. Cell Biol. **[2024](https://doi.org/10.1016/j.biocel.2024.106615)**, 173: 106615. (published on 2024 8 1) [https://doi.org/10.1016/j.biocel.2024.106615](https://doi.org/10.1016/j.biocel.2024.106615)

1. **Solvatochromic fluorescent ethynyl naphthalimide derivatives for detection of water in organic solvents**, Nhu, Q. P. N.; Abedi, S. A. A.; Chanmungkalakul, S.; Sukwattanasinitt, M.; Chang, Y. T.*; Rashatasakhon, P.* Dyes Pigments **[2024](https://doi.org/10.1016/j.dyepig.2024.112188)**, 227:112188. (published on 2024 8 1) [https://doi.org/10.1016/j.dyepig.2024.112188](https://doi.org/10.1016/j.dyepig.2024.112188)

1. **Development of a specific fluorescent probe to detect advanced glycation end products (AGEs)**,  Cho, H.; Hong, N. K.; Yong, I.; Kwon, H. Y.; Kang, N. Y.; Ciaramicoli, L. M.; Kim, P.; Chang, Y. T. J. Mater. Chem. B. **[2024](https://doi.org/10.1039/d4tb00590b)**, 12(25), 6155-6163. (published on 2024 6 27) [https://doi.org/10.1039/d4tb00590b](https://doi.org/10.1039/d4tb00590b)

1. **The Effect of 3D-Printed Sequential Dual Drug-Releasing Patch on the Capsule Formation Around the Silicone Implant in a Rat Model**, Kim, H. B.; Jo, Y.; Woo, S. H.; Han, S. Y.; Lee, S. H.; Chang, Y. T.; Park, J. Y.; Jang, J.; Han, H. H. Aesthet. Surg. J. **[2024](https://doi.org/10.1093/asj/sjae008)**, 44(6), NP411-NP420. (published on 2024 5 15) [https://doi.org/10.1093/asj/sjae008](https://doi.org/10.1093/asj/sjae008)

1. **Targeting Heme Oxygenase 2 (HO2) with TiNIR, a Theragnostic Approach for Managing Metastatic Non-Small Cell Lung Cancer**, Mun, S. K.; Sim, H. B.; Lee, J. H.; Kim, H.; Park, D. H.; Lee, Y. A.; Han, J. Y.; Choi, Y. J.; Son, J. S.; Park, J.; Lim, T. H.; Yee, S. T.; Chang, Y. T.; Lee, S.; Chang, D. J.; Kim, J. J. Biomater. Res. **[2024](https://spj.science.org/doi/10.34133/bmr.0026)**, 28, 0026. (published on 2024 4 25) [https://spj.science.org/doi/10.34133/bmr.0026](https://spj.science.org/doi/10.34133/bmr.0026)

1. **Development of a Mature B Lymphocyte Probe through Gating-Oriented Live-Cell Distinction (GOLD) and Selective Imaging of Topical Spleen**, Cho, H.; Kwon, H. Y.; Kim, Y.; Kim, K.; Lee, E. J.; Kang, N. Y.; Chang, Y. T.* JACS Au **[2024](https://pubs.acs.org/doi/10.1021/jacsau.4c00001)**, 4, 1450-1457. (published on 2024 4 22) [https://pubs.acs.org/doi/10.1021/jacsau.4c00001](https://pubs.acs.org/doi/10.1021/jacsau.4c00001)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163732_4sgXI7iwrBCfb0gMP2?q=80&s=1280x180&t=outside&f=webp)

1. **Discovery of Live Cell Selective Fluorescent Probes and Elucidation of Their Mechanisms: Case Study of B Cell Selective Probe CDgB**, Kwon, H. Y.; Chang, Y. T.; Kang, N. Y. Methods Mol. Biol. **2024**, 2779, pp305-321. (published on 2024 3 26) [https://doi.org/10.1007/978-1-0716-3738-8_14](https://doi.org/10.1007/978-1-0716-3738-8_14)

1. **Novel Fluorescent Strategy for Discriminating T and B Lymphocytes Using Transport System**, Cho, H.; Hong, N. K.; Chang, Y. T.* Pharmaceutics **2024**, 16(3):424 (published 2024 3 19) [https://doi.org/10.3390/pharmaceutics16030424](https://doi.org/10.3390/pharmaceutics16030424)

1. **Distinct chemical environments in biomolecular condensates**, Kilgore, H. R.; Mikhael, P. G.; Overholt, K. J.; Boija, A.; Hannett, N. M.; Van Dongen, C.; Lee, T. I.; Chang, Y. T.; Barzilay, R.; Young, R. A. Nat. Chem. Biol. **2024**, 20(3), 291-301. (published on 2024 3 1)  [https://doi.org/10.1038/s41589-023-01432-0](https://doi.org/10.1038/s41589-023-01432-0)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163826_ZPDnzPenI0PFGekilb?q=80&s=1280x180&t=outside&f=webp)

1. **NeuM: A Neuron-Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin-Mediated Endocytosis in Primary Neurons**, Sung, Y.; Gotina, L.; Kim, K. H.; Lee, J. Y.; Shin, S.; Aziz, H.; Kang, D. M.; Liu, X.; Hong, N. K.; Lee, H. G.; Lee, J. S.; Ku, H.; Jeong, C.; Pae, A. N.; Lim, S.*; Chang, Y. T.*; Kim, Y. K.* Angew. Chem. Int. Ed. Engl. **2024**, 63(3), e202312942. (published on 2024 1 15) [https://doi.org/10.1002/anie.202312942](https://doi.org/10.1002/anie.202312942)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163850_TJd8A9z07blHttinJA?q=80&s=1280x180&t=outside&f=webp)

1. **Chronological development of functional fluorophores for bio-imaging**, Munan, S.; Chang, Y. T.*; Samanta, A.* Chem. Commun. **[2024](https://doi.org/10.1039/d3cc04895k)**, 60(5), 501-521 (published on 2024 1 11) [https://doi.org/10.1039/d3cc04895k](https://doi.org/10.1039/d3cc04895k)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/163945_K798CIocX5cRYnlDNI?q=80&s=1280x180&t=outside&f=webp)

1. **Mitochondrial temperature homeostasis resists external metabolic stresses**, Terzioglu, M.; Veeroja, K.; Montonen, T.; Ihalainen, T. O.; Salminen, T. S.; Bénit, P.; Rustin, P.; Chang, Y. T.; Nagai, T.; Jacobs, H. T. eLife **[2023](https://doi.org/10.7554/elife.89232)**, 12, RP89232. (published on 2023 12 11) [https://doi.org/10.7554/elife.89232](https://doi.org/10.7554/elife.89232)

1. **The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk**, Clement, D.; Szabo, E. K.; Krokeide, S. Z.; Wiiger, M. T.; Vincenti, M.; Palacios, D.; Chang, Y. T.; Grimm, C.; Patel, S.; Stenmark, H.; Brech, A.; Majhi, R. K.; Malmberg, K. J. J Immunol. **2023**, 211(9), 1348-1358. (published on 2023 11 1) [https://doi.org/10.4049/jimmunol.2300406](https://doi.org/10.4049/jimmunol.2300406)

1. **Menthol causes mitochondrial Ca2+-influx, affects structure-function relationship and cools mitochondria**, Kumar, S.; Acharya, T. K.; Halder, R. R.; Mahapatra, P.; Chang, Y. T.; Goswami, C. Life Sci. **[2023](https://doi.org/10.1016/j.lfs.2023.122032)**, 331:122032 (published on 2023 10 15) [https://doi.org/10.1016/j.lfs.2023.122032](https://doi.org/10.1016/j.lfs.2023.122032)

1. **Development of Iodinated Indocyanine Green Analogs as a Strategy for Targeted Therapy of Liver Cancer**, Marker, S. C.; Espinoza, A. F.; King, A. P.; Woodfield, S. E.; Patel, R. H.; Baidoo, K.; Nix, M. N.; Ciaramicoli, L. M.; Chang, Y. T.; Escorcia, F. E.; Vasudevan, S. A.; Schnermann, M. J. ACS Med. Chem. Lett. **2023**, 14(9),1208-1215. (published on 2023 8 24) [https://doi.org/10.1021/acsmedchemlett.3c00213](https://doi.org/10.1021/acsmedchemlett.3c00213)

1. **Magnetically Enhanced Intracellular Uptake of Superparamagnetic Iron Oxide Nanoparticles for Antitumor Therapy**, Choi, J.; Kim, D. I.; Kim, J. Y.; Pané, S.; Nelson, B. J.; Chang, Y. T.; Choi, H. ACS Nano **[2023](https://doi.org/10.1021/acsnano.3c03780)**, 17(16), 15857-15870. (published on 2023 8 23) [https://doi.org/10.1021/acsnano.3c03780](https://doi.org/10.1021/acsnano.3c03780)

1. **Improved tropoelastin synthesis in the skin by codon optimization and nucleotide modification of tropoelastin-encoding synthetic mRNA**, Golombek, S.; Hoffmann, T.; Hann, L.; Mandler, M.; Schmidhuber, S.; Weber, J.; Chang, Y. T.; Mehling, R.; Ladinig, A.; Knecht, C.; Leyens, J.; Schlensak, C.; Wendel, H. P.; Schneeberger, A.; Avci-Adali, M. Mol. Ther. Nucleic Acids **[2023](https://doi.org/10.1016/j.omtn.2023.07.035)**, 33, 642-654. (published on 2023 8 2) [https://doi.org/10.1016/j.omtn.2023.07.035](https://doi.org/10.1016/j.omtn.2023.07.035)

1. **Chemical probes based on GOLD: The discovery and elucidation of mechanism**, Ciaramicoli, L. M.; Chang, Y. T.* Bull. Korean Chem. Soc. **[2023](http://dx.doi.org/10.1002/bkcs.12713)**, 44, 679-692. (published on 2023 8 1) [http://dx.doi.org/10.1002/bkcs.12713](http://dx.doi.org/10.1002/bkcs.12713)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/164203_TFwCIVzQsYi8geaXDH?q=80&s=1280x180&t=outside&f=webp)

1. **NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid**, Lee, H. G.; Hong, N. K.; Chang, Y. T.* Chem. Commun. **[2023](https://doi.org/10.1039/D3CC02501B)**, 59, 9372-9375. (published on 2023 7 27) [https://doi.org/10.1039/D3CC02501B](https://doi.org/10.1039/D3CC02501B)

1. **Applicability and limitations of fluorescence intensity-based thermometry using a palette of organelle thermometers**, Yamazaki, T.; Liu, X.; Chang, Y. T.; Arai, S. Chemosensors **[2023](https://doi.org/10.3390/chemosensors11070375)**, 11, 375. (published on 2023 7 4) [https://doi.org/10.3390/chemosensors11070375](https://doi.org/10.3390/chemosensors11070375)

1. **Visualization of Metastatic Lung Cancer with TiNIR**, Mun, S. K.; Sim, H. B.; Han, J. Y.; Kim, H.; Park, D. H.; Chang, D. J.; Yee, S. T.*; Chang, Y. T.*; Kim, J. J.* Tomography **[2023](https://doi.org/10.3390/tomography9040096)**, 9, 1187-1195. (published on 2023 6 21) [https://doi.org/10.3390/tomography9040096](https://doi.org/10.3390/tomography9040096)

1. **Quantitative Structure-Activity Relationship of Fluorescent Probes and Their Intracellular Localizations**, Park, S. H.; Lee, H. G.; Liu, X; Lee, S. K.*; Chang, Y. T.* Chemosensors**[ 2023](https://doi.org/10.3390/chemosensors11050310)**, 11, 310. (published on 2023 5 22) [https://doi.org/10.3390/chemosensors11050310](https://doi.org/10.3390/chemosensors11050310)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/164308_RuvQVorIzJatfOmvar?q=80&s=1280x180&t=outside&f=webp)

1. **Distinctive Labeling of Live Monocytes and Neutrophils with a Single Fluorescent Molecule**, Kim, S.; Fukud, M.; Lee, J. Y.; Chang, Y. T.; Je, S.; Kim, B. Chemosensors **[2023](https://doi.org/10.3390/chemosensors11050265)**, 11, 265. (published on 2023 4 29) [https://doi.org/10.3390/chemosensors11050265](https://doi.org/10.3390/chemosensors11050265)

1. **TRPV4 regulates mitochondrial Ca2+-status and physiology in primary murine T cells based on their immunological state**, Acharya, T. K.; Kumar, S.; Rokade, T. P.; Chang, Y. T.; Goswami, C. Life Sci. **[2023](https://doi.org/10.1016/j.lfs.2023.121493)**, 318: 121493. (published on 2023 4 1) [https://doi.org/10.1016/j.lfs.2023.121493](https://doi.org/10.1016/j.lfs.2023.121493)

1. **A Photoinduced Electron Transfer-Based Hypochlorite-Specific Fluorescent Probe for Selective Imaging of Proinflammatory M1 in a Rheumatoid Arthritis Model**, Baruah, M.; Kwon, H. Y.; Cho, H.; Chang, Y. T.*; Samanta, A.* Anal. Chem. **[2023](https://doi.org/10.1021/acs.analchem.2c05218)**, 95(8), 4147-4154. (published on 2023 2 28) [https://doi.org/10.1021/acs.analchem.2c05218](https://doi.org/10.1021/acs.analchem.2c05218)

1. **Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer**, Lee, Y. A.; Lek, C. C. J.; Rong, G. Wu, Z; Shathishwaran, S.; Lee, J. H. J.; Tam, W. L.; Wuestefeld, T.; Park, S. J.; Jung, S.; Kim, B.; Kang, N. Y.*; Chang, Y. T.* Theranostics **[2023](https://doi.org/10.7150/thno.79282)**, 13, 1370-1380. (published on 2023 2 21) [https://doi.org/10.7150/thno.79282](https://doi.org/10.7150/thno.79282)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/164454_yQrEvQ9Oe4mra3kVQu?q=80&s=1280x180&t=outside&f=webp)

1. **Development of a Fluorescent Probe for M2 Macrophages via Gating-Oriented Live-Cell Distinction**, Cho, H.; Kwon, H. Y.; Lee, S. H.; Lee, H. G.; Kang, N. Y.*; Chang, Y. T.* J. Am. Chem. Soc. **[2023](https://doi.org/10.1021/jacs.2c11393)**, 145, 2951-2957. (published on 2023 2 8) [https://doi.org/10.1021/jacs.2c11393](https://doi.org/10.1021/jacs.2c11393)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/164520_EEZG98VNme8ZjF0q33?q=80&s=1280x180&t=outside&f=webp)

1. **Diversity-oriented fluorescence library approach: accelerating probe development for biological and environmental applications**, Samata, A.*; Munan, S.; Jana, A.; Chang, Y. T.* Fluorescent Chemosensors, Eds. James, T. D.; Wu, L.; Sedgwick, A.C; He, X. P. Monographs in Supramolecular Chemistry No. 34, The Royal Society of Chemistry **2023**. (published in 2023)

1. **Synthetic Monosaccharide Channels: Size-Selective Transmembrane Transport of Glucose and Fructose Mediated by Porphyrin Boxes**, Lee, H. G.; Dhamija, A.; Das, C. K.; Park, K. M.; Chang, Y. T.; Schäfer, L. V.; Kim, K. Angew. Chem. Int. Ed. Engl. **[2023](https://doi.org/10.1002/anie.202214326)**, 62, e202214326. (published on 2023 1 9) [https://doi.org/10.1002/anie.202214326](https://doi.org/10.1002/anie.202214326)

1. **Fluorescent Janus ring siloxanes for detection of Au(III) and l-cysteine, Chaiprasert**, T.; Chanmungkalakul, S.; Liu, Y.; Bureerug, T.; Silpcharu, K.; Unno, M.; Liu, X.; Ervithayasuporn, V.; Chang, Y. T .*; Rashatasakhon, P.* Dyes Pigments **[2022](https://doi.org/10.1016/j.dyepig.2022.110793)**, 208:110793. (published on 2022 12 1)  [https://doi.org/10.1016/j.dyepig.2022.110793](https://doi.org/10.1016/j.dyepig.2022.110793)

1. **Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer’s disease**, Yang, H.; Park, S. Y.; Baek, H.; Lee, C.; Chung, G.; Liu, X.; Lee, J. H.; Kim, B.; Kwon, M.; Choi, H.; Kim, H. J.; Kim, J. Y.; Kim, Y.; Lee, Y. S.; Lee, G.; Kim, S. K.; Kim, J. S.; Chang, Y. T.; Jung, W. S.; Kim, K. H.; Bae, H. Theranostics **[2022](https://doi.org/10.7150/thno.75965)**, 12, 7668-7680. (published on 2022 11 7) [https://doi.org/10.7150/thno.75965](https://doi.org/10.7150/thno.75965)

1. **TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism**, Acharya, T. K.; Kumar, A.; Majhi, R. K.; Kumar, S.; Chakraborty, R.; Tiwari, A.; Smalla, K. H.; Liu, X.; Chang, Y. T.; Gundelfinger, E. D.; Goswami, C. Mitochondrion **2022**, 67, 38-58. (published on 2022 11 1)  [https://doi.org/10.1016/j.mito.2022.10.001](https://doi.org/10.1016/j.mito.2022.10.001)

1. **Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target**, Cho, H.; Kwon, H. Y.; Sharma, A.; Lee, S. H.; Liu, X.; Miyamoto, N.; Kim, J. J., Im, S. H.; Kang, N. Y.; Chang, Y. T .* Nat. Commun. **[2022](https://doi.org/10.1038/s41467-022-33526-z)**, 13:5974 (published on 2022 10 10)  [https://doi.org/10.1038/s41467-022-33526-z](https://doi.org/10.1038/s41467-022-33526-z)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/164656_vLrtpGE0GBEKWxy0Wp?q=80&s=1280x180&t=outside&f=webp)

1. **SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA**, Maharana, S.; Kretschmer, S.; Hunger, S.; Yan, X.; Kuster, D.; Traikov, S.; Zillinger, T.; Gentzel, M.; Elangovan, S.; Dasgupta, P.; Chappidi, N.; Lucas, N.; Maser, K. I.; Maatz, H.; Rapp, A.; Marchand, V.; Chang, Y. T.; Motorin, Y.; Hubner, N.; Hartmann, G.; Hyman, A. A.; Alberti, S.; Lee-Kirsch, M. A. Mol Cell **[2022](https://doi.org/10.1016/j.molcel.2022.08.031)**, 82, 3712-3728.e10. (published on 2022 10 6)  [https://doi.org/10.1016/j.molcel.2022.08.031](https://doi.org/10.1016/j.molcel.2022.08.031)

1. **Human T cell-selective fluorescent probe**, Gao, M.; Chang, Y. T.* Cells **[2022](https://doi.org/10.3390/cells11182836)**, 11, 2836. (published on 2022 9 11)  [https://doi.org/10.3390/cells11182836](https://doi.org/10.3390/cells11182836)

1. **A palette of site-specific organelle fluorescent thermometers**, Liu, X.; Yamazaki, T.; Kwon, H. Y.; Arai, S.*; Chang, Y. T.* Mater Today Bio. **[2022](https://doi.org/10.1016/j.mtbio.2022.100405)**, 16, 100405. (published on 2022 8 19)  [https://doi.org/10.1016/j.mtbio.2022.100405](https://doi.org/10.1016/j.mtbio.2022.100405)

1. **Nanomaterials-based imaging diagnosis and therapy of cardiovascular diseases**, Zhong, Y.; Zeng, X.; Zeng, Y.; Yang, L.; Peng, J.*; Zhao, L.*; Chang, Y. T.* Nano Today **[2022](https://doi.org/10.1016/j.nantod.2022.101554)**, 45: 101554.  (published on 2022 8 1) [https://doi.org/10.1016/j.nantod.2022.101554](https://doi.org/10.1016/j.nantod.2022.101554)

1. **A SLC35C2 transporter-targeting fluorescent probe for the selective detection of B lymphocytes identified by SLC-CRISPRi and unbiased fluorescence library screening**, Gao, M.; Lee, S. H.; Das, R. K.; Kwon, H. Y.; Kim, H. S.; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. 2022, 61, 202202095. (published on 2022 9 5)  [https://doi.org/10.1002/anie.202202095](https://doi.org/10.1002/anie.202202095)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/165058_PRbE2P7q9tPxNrULNn?q=80&s=1280x180&t=outside&f=webp)

1. **Mechanism assay of interaction between blood vessels-near infrared probe and cell surface marker proteins of endothelial cells**, Sisak, M. A. A.; Louis, F.; Miyao, T.; Lee, S. H.; Chang, Y. T.; Matsusaki, M. Mater. Today Bio **[2022](https://doi.org/10.1016/j.mtbio.2022.100332)**, 15: 100332. (published on 2022 6 23)  [https://doi.org/10.1016/j.mtbio.2022.100332](https://doi.org/10.1016/j.mtbio.2022.100332)

1. **ABCB1 can actively pump-out the background-free tame fluorescent probe CO-1 from live cells**, Ciaramicoli, L. M.; Kim, H. S.; Alamudi, S. H.*; Chang, Y. T.* Chem. Asian J. **[2022](https://doi.org/10.1002/asia.202200229)**, 17, e202200229. (published on 2022 6 15)  [https://doi.org/10.1002/asia.202200229](https://doi.org/10.1002/asia.202200229)

1. **Casting red light for bad oil by dual turning-on mechanisms of fluorescence and its application in the portable platform**, Liu, X.; Choi, E. G.; Cui, S.; Kumara, K.; Cho, M.; Chang, Y. T.* Sens. Actuators B Chem. **2022**, 365, 131866. (published on 2022 8 15)  [https://doi.org/10.1016/j.snb.2022.131866](https://doi.org/10.1016/j.snb.2022.131866)

1. **Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice**, Park, S. Y.; Yang, H.; Ye, M.; Liu, X.; Shim, I.; Chang, Y. T.; Bae, H. J. Neuroinflammation **[2022](https://doi.org/10.1186/s12974-022-02512-z)**, 19, 143. (published on 2022 6 11)  [https://doi.org/10.1186/s12974-022-02512-z](https://doi.org/10.1186/s12974-022-02512-z)

1. **Contagious Aggregation: Transmittable Protein Aggregation in Cellular Communities Initiated by Synthetic Cells**, Lee, H. G.; Kim, J. H.; Gorai, T.; Ko, Y. H.; Kwon, H. Y.; Chung, W.; Hwang, I.; Lim, S.; Kim, Y. K.; Shin, K.; Chang, Y. T.*; Kim, K.*; Park, K. M.* J. Am. Chem. Soc. **[2022](https://doi.org/10.1021/jacs.1c13545)**, 144, 5067-5073. (published on 2022 3 23)  [https://doi.org/10.1021/jacs.1c13545](https://doi.org/10.1021/jacs.1c13545) 

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/165217_nzt7dyJhdN1yunc9zy?q=80&s=1280x180&t=outside&f=webp)

1. **Live isolation of naïve ESCs via distinct glucose metabolism and stored glycogen**, Kim, K. T.; Oh, J. Y.; Park, S.; Kim. S. M.; Benjamin, P.; Park, I. H.; Chun, K. H.; Chang, Y. T.; Cha, H. J. Metab. Eng. **[2022](https://doi.org/10.1016/j.ymben.2022.03.003)**, 72, 97-106. (published on 2022 3 10)  [https://doi.org/10.1016/j.ymben.2022.03.003](https://doi.org/10.1016/j.ymben.2022.03.003) 

1. F**luorescent probe strategy for live cell distinction**, Liu, X.; Chang, Y. T.* Chem. Soc. Rev. **2022**, 51, 1573-1591. (published on 2022 3 7)  [https://doi.org/10.1039/d1cs00388g](https://doi.org/10.1039/d1cs00388g)

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/165253_RX5njmbBgawUfJqSrC?q=80&s=1280x180&t=outside&f=webp)

1. **Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library**, Miyamoto, N.; Go, Y. H.; Ciaramicoli, L. M.; Kwon, H. Y.; Kim, H. S.; Bi, X.; Yu, Y. H.; Kim, B.; Ha, H.; Kang, N. Y.; Yun, S. W.; Kim, J. S.; Cha, H. J.*; Chang, Y. T.* RSC Chem. Biol. **2021**, 2, 1590-1593.

1. **Neutrophil Selective Fluorescent Probe Development through Metabolism-Oriented Live-cell Distinction**, Gao, M.; Lee, S. H.; Park, S. H.; Ciaramicoli, L. M.; Kwon, H. Y.; Cho, H.; Jeong, J.; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. **2021**, 60, 23742-23749.

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/165450_3zl14BUSNTGlvLtbl7?q=80&s=1280x180&t=outside&f=webp)

1. **The screening of drug-induced nephrotoxicity using gold nanocluster-based ratiometric fluorescent probes**, Liu, Q.; Li, J.; Liu, X.; Yuan, L.; Zhao, L.; Chang, Y. T.; Liu, X.; Peng, J. Nanoscale **2021**, 13, 13835-13844.

1. **A Near-Infrared Organic Fluorescent Probe for Broad Applications for Blood Vessels Imaging by High-throughput Screening via 3D-Blood Vessel Models**, Sisak, M. A. A.; Louis, F.; Aoki, I.; Lee, S. H.; Chang, Y. T.; Matsusaki, M. Small Methods **2021**, 5, 2100338.

1. **Diversity-Oriented Fluorescence Library Approach (DOFLA) for Discovery of Cell-Permeable Probes for Applications in Live Cell Imaging**, Su, D.; Chang, Y. T.* in “Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery (Methods in Pharmacology and Toxicology series)”, pp 179-197, Eds. Rosania, G. R. and Thurber, G. M., Humana press: New York, **2021**.

1. **Blue-conversion of organic dyes produces artifacts in multicolor fluorescence imaging**, Kim, D. H.; Chang, Y.; Park, S.; Jeong, M. G.; Kwon, Y.; Zhou, K.; Noh, J.; Choi, Y. K.; Hong, T. M.; Chang, Y. T.; Ryu, S. H. Chem. Sci. **2021**, 12, 8660-8667.

1. **Azide-based bioorthogonal chemistry: Reactions and its advances in cellular and biomolecular imaging**, Alamudi, S. H.; Liu, X.; Chang, Y. T.* Biophysics Rev. **2021**, 2, 021301.

1. **Application of Neuron-Selective Fluorescent Probe, NeuA, To Identify Mouse Retinal Degeneration**, Park, S. J.; Woon, Q. T. S.; Er, J. C.; Wong, B. H.; Liu, X.; Kang, N. Y.; Barathi, V. A.; Silver, D. L.; Chang, Y. T.* ChemBioChem **2021**, 22, 1915-1919.

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/165705_DYFWBCdHjBfX8fz87n?q=80&s=1280x180&t=outside&f=webp)

1. **[Lipid-Oriented Live-Cell Distinction of B and T Lymphocytes](https://pubs.acs.org/doi/10.1021/jacs.1c00944)**[,](https://pubs.acs.org/doi/10.1021/jacs.1c00944) Kwon, H. Y.; Kumar Das, R.; Jung, G. T.; Lee, H. G.; Lee, S. H.; Berry, S. N.; Tan, J. K. S.; Park, S.; Yang, J. S.; Park, S.; Baek, K.; Park, K. M.; Lee, J. W.; Choi, Y. K.; Kim, K. H.; Kim, S.; Kim, K. P.; Kang, N. Y.*; Kim, K.*; Chang, Y. T.* J. Am. Chem. Soc. **2021**, 143, 5836-5844.

![Image](https://upload.cafenono.com/image/slashpageHome/20250415/165751_PdJHuQeg8iY5B9zQNE?q=80&s=1280x180&t=outside&f=webp)

1. **[Gynura divaricata water extract presented the possibility to enhance neuronal regeneration](https://onlinelibrary.wiley.com/doi/10.1155/2021/8818618)**, Kantawong, F.; Saisuwan, C.; Soeratanapant, P.; Wanachantararak, P.; Nan, J.; Wu, J.; Chang, Y. T. Evid. Based Complement. Alternat. Med. **2021**, 8818618.

1. **[Novel live cell fluorescent probe for human-induced pluripotent stem cells highlights early reprogramming population](https://stemcellres.biomedcentral.com/articles/10.1186/s13287-021-02171-6)**, Sriram, S.; Kang, N. Y.; Subramanian, S.; Nandi, T.; Sudhagar, S.; Xing, Q.; Tong, G. J.; Chen, A. K.; Srijaya, T. C.; Tan, P.; Loh, Y. H.; Chang, Y. T.; Sugii, S. Stem Cell Res. Ther. **2021**, 12, 113.

1. **[Neuronal Migration on Silicon Microcone Arrays with Different Pitches](https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.202000583)**, Seo, J.; Lanara, C.; Choi, J. Y.; Kim, J.; Cho, H.; Chang, Y. T.; Kang, K.; Stratakis, E.; Choi, I. S. Adv. Healthc. Mater. **2021**, 10, e2000583.

1. **[A Systematic Study on the Relationship Between Viscosity Sensitivity and Temperature Dependency of BODIPY Rotors](https://onlinelibrary.wiley.com/doi/full/10.1002/bkcs.12110)**, Liu, X.; Chi, W.; Gómez‐Infante, A. J.; Peña‐Cabrera, E.; Liu, X.*; Chang, Y. T.* Bull. Korean Chem. Soc. **2021**, 42, 91-94.

1. **[Click and count: specific detection of acid ceramidase activity in live cells, Casasampere, M.; Izquierdo](https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc03166f#!divAbstract)**, E.; Casas, J.; Abad, J. L.; Liu, X.; Xu, R.; Mao, C.; Chang, Y. T.; Delgado, A.; Fabrias, G. Chem. Sci. **2020**, 11, 13044-13051.

1. [F](https://pubs.acs.org/doi/10.1021/acsabm.0c00345)**[luid-Matrix Interface Triggers a Heterogeneous Activation of Macrophages](https://pubs.acs.org/doi/10.1021/acsabm.0c00345)**, Jo, Y.; Kim, H. M.; Lee, J.; Lee, C.; Hugonnet, H.; Park, Y. K.; Liu, X.; Chang, Y. T.; Kim, H.; Kim, P. ACS Appl. Bio. Mater. **2020**, 3, 4294-4301.

1. **[Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing](https://www.science.org/doi/10.1126/sciadv.aba1190)**, Xing, Q. R.; El Farran, C. A.; Gautam, P.; Chuah, Y. S.; Warrier, T.; Toh, C. X. D.; Kang, N. Y.; Sugii, S.; Chang, Y. T.; Xu, J.; Collins, J. J.; Daley, G. Q.; Li, H.; Zhang, L. F.; Loh, Y. H. Sci. Adv. **2020**, 6, eaba1190.

1. **[CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice](https://www.science.org/doi/10.1126/scitranslmed.aaz8664)**, Wang, C. H.; Lundh, M.; Fu, A.; Kriszt, R.; Huang, T. L.; Lynes, M. D.; Leiria, L. O.; Shamsi, F.; Darcy, J.; Greenwood, B. P.; Narain, N. R.; Tolstikov, V.; Smith, K. L.; Emanuelli, B.; Chang, Y. T.; Hagen, S.; Danial, N. N.; Kiebish, M. A.; Tseng, Y. H. Sci. Transl. Med. **2020**, 12, eaaz8664.

1. **[Target identification of a macrocyclic hexaoxazole G-quadruplex ligand using post-target-binding visualization](https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc04957c#!divAbstract)**, Yasuda, M.; Ma, Y.; Okabe, S.; Wakabayashi, Y.; Su, D.; Chang, Y. T.; Seimiya, H.; Tera, M.; Nagasawa, K. Chem. Commun. **2020**, 56, 12905-12908.

1. **[Pitfalls in Monitoring Mitochondrial Temperature Using Charged Thermosensitive Fluorophores](https://www.mdpi.com/2227-9040/8/4/124)**, Chrétien, D.; Bénit, P.; Leroy, C.; El-Khoury, R.; Park, S.; Lee, J. Y.; Chang, Y. T.; Lenaers, G.; Rustin, R.; Rak, M. Chemosensors **2020**, 8, 124.

1. [F](https://www.mdpi.com/2072-666X/11/8/727)**[abrication of Blood Capillary Models for Live Imaging Microarray Analysis](https://www.mdpi.com/2072-666X/11/8/727)**, Abdul Sisak, M. A.; Louis, F.; Lee, S. H.; Chang, Y. T.; Matsusaki, M. Micromachines** 2020**, 11, 727.

1. **[Partitioning of cancer therapeutics in nuclear condensates](https://www.science.org/doi/10.1126/science.aaz4427)**, Klein, I. A.; Boija, A.; Afeyan, L. K.; Hawken, S. W.; Fan, M.; Dall’Agnese, A.; Oksuz, O.; Henninger, J. E.; Shrinivas, K.; Sabari, B. R.; Sagi, I.; Clark, V. E.; Platt, J. M.; Kar, M.; McCall, P. M.; Zamudio, A. V.; Manteiga, J. C.; Coffey, E. L.; Li, C. H.; Hannett, N. M.; Guo, Y. E.; Decker, T. M.; Lee, T. I.; Zhang, T.; Weng, J. K.; Taatjes, D. J.; Chakraborty, A.; Sharp, P. A.; Chang, Y. T.; Hyman, A. A.; Gray, N. S.; Young, R. A. Science **2020**, 368, 1386-1392. 

1. **[Direct monitoring of live human pluripotent stem cells by a highly selective pluripotency sensor](https://www.sciencedirect.com/science/article/pii/S0960894X20304583?dgcid=rss_sd_all)**, Park, M. R.; Nam, D.; Lee, H.; Chang, Y. T.; Zaehres, H.; Kim, J. B. Bioorg. Med. Chem. Lett. **2020**, 30, 127347. 

1. **[Validation of CDr15 as a new dye for detecting neutrophil extracellular trap](https://www.sciencedirect.com/science/article/pii/S0006291X20308974)**, Kim, S. J.; Kim, J.; Kim, B.; Lee, W. W.; Liu, X.; Chang, Y. T.; Park, J. W. Biochem. Biophys. Res. Commun. **2020**, 527, 646-653. 

1. **[A genetically validated approach to detect inorganic polyphosphates in plants](https://onlinelibrary.wiley.com/doi/full/10.1111/tpj.14642)**, Zhu, J.; Loubery, S.; Broger, L.; Zhang, Y.; Lorenzo-Orts, L.; Utz-Pugin, A.; Chang, Y. T.; Hothorn, M.; Fernie, A.; Hothorn, M. Plant J. **2020**, 102, 507-516.

1. **[RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation](https://www.sciencedirect.com/science/article/pii/S0092867420303421)**, Guillén-Boixet, J.; Kopach, A.; Holehouse, A. S.; Wittmann, S.; Jahnel, M.; Schlüßler, R.; Kim, K.; Trussina, I. R. E. A.; Wang, J.; Mateju, D.; Poser, I.; Maharana, S.; Ruer-Gruß, M.; Richter, D.; Zhang, X.; Chang, Y. T.; Guck, J.; Honigmann, A.; Mahamid, J.; Hyman, A. A.; Pappu, R. V.; Alberti, S.; Franzmann, T. M. Cell **2020**, 181, 346-361.

1. **[A General Descriptor ΔE Enables the Quantitative Development of Luminescent Materials Based on Photoinduced Electron Transfer](https://pubs.acs.org/doi/10.1021/jacs.0c01473)**, Chi, W.; Chen, J.; Liu, W.; Wang, C.; Qi, Q.; Qiao, Q.; Tan, T. M.; Xiong, K.; Liu, X.; Kang, K.; Chang, Y. T.*; Xu, Z.*; Liu, X.* J. Am. Chem. Soc. **2020**, 142, 6777-6785.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/132404_lW1jyNvbA8AZYdNCrw?q=80&s=1280x180&t=outside&f=webp)

1. **[Molecular Mechanism of Viscosity Sensitivity in BODIPY Rotors and Application to Motion-Based Fluorescent Sensors](https://pubs.acs.org/doi/10.1021/acssensors.9b01951)**, Liu, X.; Chi, W.; Qiao, Q.; Kokate, S. V.; Cabrera, E. P.; Xu, Z.; Liu, X.; Chang, Y. T.* ACS Sens **2020**, 5, 731-739.

1. **[Multimodal imaging probe development for pancreatic β-cells: from fluorescence to PET](https://pubs.acs.org/doi/full/10.1021/jacs.9b11173)**, Kang, N. Y.; Lee, J.; Lee, S. H.; Song, I. H.; Hwang, Y. H.; Kim, M. J.; Phue, W. H.; Agrawalla, B. K.; Wan, S. Y. D.; Lalic, J.; Park, S. J.; Kim, J. J.; Kwon, H. Y.; Im, S. H.; Bae, M. A.; Ahn, J. H.; Lim, C. S.; Teo, A. K. K.; Park, S.; Kim, S. E.; Lee, B. C.; Lee, D. Y.*; Chang, Y. T.* J. Am. Chem. Soc. **2020**, 142, 3430-3439.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/132458_EHVRcnYpvjU4OGqOId?q=80&s=1280x180&t=outside&f=webp)

1. **[A mouse ear skin model to study the dynamics of innate immune responses against Staphylococcus aureus biofilms](https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-019-1635-z)**, Abdul Hamid, A. I.; Nakusi, L.; Givskov, M.; Chang, Y. T.; Marquès, C.; Gueirard, P. BMC Microbiol. **2020**, 20:22.

1. **[Identification of a novel turn-on albumin binding small-molecule bioprobe in live zebrafish and its potential application in drug discovery](https://www.sciencedirect.com/science/article/pii/S0143720819311179)**, Chun, H. S.; Han S. J.; Shin, D. S.; Pagire, H. S.; Pagire, S. H.; Lee, G. B.; Chae, C. H.; Pak, B.; Jin, S. W.; Chang, Y. T.; Park, S. B.; Ahn, J. H.*; Bae, M. A.* Dyes Pigments **2019**, 171, 107720.

1. **[Holding-Oriented versus Gating-Oriented Live-Cell Distinction: Highlighting the Role of Transporters in Cell Imaging Probe Development](https://pubs.acs.org/doi/10.1021/acs.accounts.9b00253)**, Choi, Y. K.; Kim, J. J.; Chang, Y. T.* Acc. Chem. Res. **2019**, 52, 3097-3107.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/132634_1O0fg6bY5MfotycHQq?q=80&s=1280x180&t=outside&f=webp)

349.[ ](https://pubs.acs.org/doi/10.1021/jacs.9b06068)**[A NIR probe tracks and treats lung tumor initiating cells by targeting HMOX2](https://pubs.acs.org/doi/10.1021/jacs.9b06068)**, Kim, J. J.; Lee, Y. A.; Su, D.; Lee, J.; Park, S. J.; Kim, B.; Lee, J. H. J.; Liu, X.; Kim, S. S.; Bae, M. A.; Lee, J. S.; Hong, S. C.; Wang, L.; Samanta, A.; Kwon, H. Y.; Choi, S. Y.; Kim, J. Y.; Yu, Y. H.; Ha, H. H.; Wang, Z.; Tam, W. L.; Lim, B.; Kang, N. Y.*; Chang, Y. T.* J. Am. Chem. Soc. **2019**, 141, 14673-14686.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/132717_h4jPd1sPeOAGNYQK0p?q=80&s=1280x180&t=outside&f=webp)

1. **[Rapid detection of senescent mesenchymal stromal cells by a fluorescent probe](https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/biot.201800691)**, Ang, J.; Lee, Y. A.; Raghothaman, D.; Jayaraman, P.; Teo, K. L.; Khan, F. J.; Reuveny, S.; Chang, Y. T.; Kang, N. Y.*; Oh, S.* Biotechnol. J. **2019**, 1800691.

1. **[Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7](https://www.nature.com/articles/s41598-019-48329-4)**, Park, S. J.; Ho, C. J. H.; Arai, S.; Samanta, A.; Olivo, M.; Chang, Y. T.* Sci. Rep. **2019**, 9, 12052.

1. **[Gold nanoparticle-based detection of dopamine based on fluorescence resonance energy transfer between a 4-(4-dialkylaminostyryl)pyridinium derived fluorophore and citrate-capped gold nanoparticles](https://link.springer.com/article/10.1007/s00604-019-3727-8)**, Peng, J.*; Zhou, N.; Zhong, Y.; Su, Y.; Zhao, L.*; Chang, Y. T.* Mikrochim. Acta. **2019**, 186, 618.

1. **[Visualizing biofilm by targeting eDNA with long wavelength probe CDr15](https://pubs.rsc.org/en/content/articlelanding/2019/bm/c9bm00152b#!divAbstract)**, Kwon, H. Y.; Kim, J. Y.; Liu, X.; Lee, J. Y.; Yam, J. K. H.; Dahl Hultqvist, L.; Xu, W.; Rybtke, M.; Tolker-Nielsen, T.; Heo, W.; Kim, J. J.;  Kang, N. Y.; Joo, T.; Yang, L.; Park, S. J.*; Givskov, M.*; Chang, Y. T.* Biomater. Sci. **2019**, 7, 3594-3598.

1. **[Cucurbitacin B induces neurogenesis in PC12 cells and protects memory in APP/PS1 mice](https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.14514)**, Li, J.; Sun, K.; Muroi, M.; Gao, L.; Chang, Y. T.; Osada, H.; Xiang, L.*; Qi, J.* J. Cell. Mol. Med. **2019**, 23, 6283-6294.

1. **[Tools for Bioimaging Pancreatic β Cells in Diabetes](https://www.sciencedirect.com/science/article/pii/S1471491419301066)**, Kang, N. Y.*; Soetedjo, A. A. P.; Amirruddin, N. S.; Chang, Y. T.; Eriksson, O.; Teo, A. K. K.* Trends Mol. Med. **2019**, 25, 708-722.

1. **[Development of a Universal Fluorescent Probe for Gram-Positive Bacteria](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201902537)**, Kwon, H. Y.; Liu, X.; Choi, E. G.; Lee, J. Y.; Choi, S. Y.; Kim, J. Y.; Wang, L.; Park, S. J.; Kim, B.; Lee, Y. A.; Kim, J. J.; Kang, N. Y.*; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. **2019**, 58, 8426-8431.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/133044_U3xyFDewLno7C5W45C?q=80&s=1280x180&t=outside&f=webp)

1. **[Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201903058)**, Kim, B.; Fukuda, M.; Lee, J. Y.; Su, D.; Sanu, S.; Silvin, A.; Khoo, A. T. T.; Kwon, T.; Liu, X.; Chi, W.; Liu, X.; Choi, S.; Wan, D. S. Y.; Park, S. J.; Kim, J. S.; Ginhoux, F.; Je, H. S._; Chang, Y. T._ Angew. Chem. Int. Ed. Engl. **2019**, 58, 7972-7976.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/134956_ZyJaOUV21FKpJkIsV4?q=80&s=1280x180&t=outside&f=webp)

1.  **[A Photoexcitation-Induced Twisted Intramolecular Charge Shuttle](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201902766)**, Chi, W.; Qiao, Q.; Lee, R.; Liu, W.; Teo, Y. S.; Gu, D.; Lang, M. J.; Chang, Y. T.*; Xu, Z.*; Liu, X.* Angew. Chem. Int. Ed. Engl. **2019**, 58, 7073-7077.

1. **[A thermoresponsive nanocarrier for mitochondria-targeted drug delivery](https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc00603f#!divAbstract)**, Wang, D.; Huang, H.; Zhou, M.; Lu, H.; Chen, J.*; Chang, Y. T.; Gao, J.*; Chai, Z.; Hu, Y.* Chem. Commun. **2019**, 55, 4051-4054.

1. **[Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target](https://www.nature.com/articles/s41467-019-08990-9)**, Park, S. J.; Kim, B.; Choi, S.; Balasubramaniam, S.; Lee, S. C.; Lee, J. Y.; Kim, H. S.; Kim, J. Y.; Kim, J. J.; Lee, Y. A.; Kang, N. Y.; Kim, J. S.*; Chang, Y. T.* Nat. Commun. **2019**, 10, 1111.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/135110_Bo3Mfl0PCqIUSzTmZ1?q=80&s=1280x180&t=outside&f=webp)

1. **[ENOblock inhibits the pathology of diet-induced obesity](https://www.nature.com/articles/s41598-018-36715-3)**, Cho, H.; Lee, J. H.; Um, J.; Kim, S.; Kim, Y.; Kim, W. H.; Kim, Y. S.; Pagire, H. S.; Ahn, J. H.; Ahn, Y.; Chang, Y. T.; Jung, D. W.*; Williams, D. R.* Sci. Rep. **2019**, 9, 493.

1. **[Advances in the design of cell-permeable fluorescent probes for applications in live cell imaging](https://pubs.rsc.org/en/Content/ArticleLanding/2018/CC/C8CC08107G#!divAbstract)**[,](https://pubs.rsc.org/en/Content/ArticleLanding/2018/CC/C8CC08107G#!divAbstract) Alamudi, S. H.; Chang, Y. T.* Chem. Commun. **2018**, 54, 13641-13653.

1. **[CDy14: a novel biofilm probe targeting exopolysaccharide Psl](https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc05544k#!divAbstract)**, Kwon, H. Y.; Kim, J. Y.; Lee, J. Y.; Yam, J. K. H.; Hultqvist, L. D.; Xu, W.; Rybtke, M.; Tolker-Nielsen, T.; Kim, J. J.; Kang, N. Y.; Yang, L.; Park, S. J.*; Givskov, M.*; Chang, Y. T.* Chem. Commun. **2018**, 54, 11865-11868.'

1. **[Efficient and wash-free labeling of membrane proteins using engineered Npu DnaE split-inteins](https://onlinelibrary.wiley.com/doi/full/10.1002/pro.3455)**, Lee, E; Min, K.; Chang, Y. T.; Kwon, Y. Protein Sci. **2018**, 27, 1568-1574.

1. **[A fluorescent chemical probe CDy9 selectively stains and enables the isolation of live naïve mouse embryonic stem cells](https://www.sciencedirect.com/science/article/pii/S0142961218304769)**, Cho, S. J.; Kim, K. T.; Kim, J. S.; Kwon, O. S.; Go, Y. H.; Kang, N. Y.; Heo, H.; Kim, M. R.; Han, D. W.; Moon, S. H.; Chang, Y. T.*; Cha, H. J.* Biomaterials **2018**, 180, 12-23.
1. 

1. **[Kakeromamide A, a new cyclic pentapeptide inducing astrocyte differentiation isolated from the marine cyanobacterium Moorea bouillonii](https://www.sciencedirect.com/science/article/pii/S0960894X18303883)**, Nakamura, F.; Maejima, H.; Kawamura, M.; Arai, D.; Okino, T.; Zhao, M.; Ye, T.; Lee, J.; Chang, Y. T.; Fusetani, N.; Nakao, Y. Bioorg. Med. Chem. Lett. **2018**, 28, 2206-2209.

1. **[Seeing Elastin: A Near-Infrared Zwitterionic Fluorescent Probe for In Vivo Elastin Imaging](https://www.cell.com/chem/fulltext/S2451-9294(18)30077-9)**, Su, D.; Teoh, C. L.; Park, S. J.; Kim, J. J.; Samanta, A.; Bi, R.; Danish, U. S.; Olivo, M.; Piantino, M.; Louis, F.; Matsusaki, M.; Kim, S. S.; Bae, M. A.; Chang, Y. T.* Chem **2018**, 4, 1128-1138.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/135355_X2bNkhk2itk24cKaIZ?q=80&s=1280x180&t=outside&f=webp)

1. [RNA buffers the phase separation behavior of prion-like RNA binding proteins](https://www.science.org/doi/10.1126/science.aar7366), Maharana, S.; Wang, J.; Papadopoulos, D. K.; Richter, D.; Pozniakovsky, A.; Poser, I.; Bickle, M.; Rizk, S.; Guillén-Boixet, J.; Franzmann, T.; Jahnel, M.; Marrone, L.; Chang, Y. T.; Sterneckert, J.; Tomancak, P.; Hyman, A. A.; Alberti, S. Science 2018, 360, 918-921.

1. [Identification of Fluorescent Small Molecule Compounds for Synaptic Labeling by Image-Based, High-Content Screening](https://pubs.acs.org/doi/full/10.1021/acschemneuro.7b00263), Dunn, M.; Boltaev, U.; Beskow, A.; Pampou, S.; Realubit, R.; Meira, T.; Silva, J. V.; Reeb, R.; Karan, C.; Jockusch, S.; Sulzer, D.; Chang, Y. T.; Sames, D.; Waites, C. L. ACS Chem Neurosci. 2018, 9, 673-683.

1. [Ultrasensitive NIR-SERRS probes with multiplexed ratiometric quantification for in vivo antibody leads validation](https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.201700870), Kang, H.; Jeong, S.; Jo, A.; Chang, H.; Yang, J. K.; Jeong, C.; Kyeong, S.; Lee, Y. W.; Samanta, A.; Maiti, K. K.; Cha, M. G.; Kim, T. K.; Lee, S.; Jun, B. H.; Chang, Y. T.; Chung, J.; Lee, H. Y.; Jeong, D. H.; Lee, Y. S. Adv. Healthc. Mater. 2018, 7, 1700870.

1. [Fluorescent squaramides as anion receptors and transmembrane anion transporters](https://pubs.rsc.org/en/content/articlelanding/2018/cc/c7cc08706c#!divAbstract), Bao, X.; Wu, X.; Berry, S. N.; Howe, E. N. W.; Chang, Y. T.; Gale, P. A. Chem. Commun. 2018, 54. 1363-1366.

1. [A palette of background-free tame fluorescent probes for intracellular multi-color labelling in live cells](https://pubs.rsc.org/en/content/articlelanding/2018/sc/c7sc04716a#!divAbstract), Alamudi, S. H.; Su, D.; Lee, K. J.; Lee, J. Y.; Belmonte-Vazquez, J. L.; Park, H. S.; Pena-Cabrera, E.; Chang, Y. T.* Chem. Sci. 2018, 9, 2376-2383.

1. [Identification of Tumor Initiating Cells by a Small Molecule Fluorescent Probe through Vimentin as the Biomarker](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201712920), Lee, Y. A.; Kim, J. J.; Lee, J.; Lee, J. H. J.; Sahu, S.; Kwon, H. Y.; Park, S. J.; Jang, S. Y.; Lee, J. S.; Wang, Z.; Tam, W. L.; Lim, B.; Kang, N. Y.*; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. 2018, 57, 2851-2854.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/135605_i8QUf7sCtXfpsRDlhs?q=80&s=1280x180&t=outside&f=webp)

1. [Silica Nanoparticle-Enhanced Fluorescent Sensor Array for Heavy Metal Ions Detection in Colloid Solution](https://pubs.acs.org/doi/full/10.1021/acs.analchem.7b02883), Peng, J.; Li, J.; Xu, W.; Wang, L.; Su, D.; Teoh, C. L.; Chang, Y. T.* Anal. Chem. 2018, 90, 1628-1634.

1. [Mitochondria are physiologically maintained at close to 50 °C, Chrétien, D.; Bénit, P.; Ha, H. H.; Keipert](https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003992), S.; El-Khoury, R.; Chang, Y. T.; Jastroch, M.; Jacobs, H. T.; Rustin, P.; Rak, M. PLoS Biol. 2018, 16, e2003992.325.

1. [Gold and hairpin DNA functionalization of upconversion nanocrystals for imaging and in vivo drug delivery](https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adma.201700244), Han, S.; Samanta, A.; Xie, X.; Huang, L.; Peng, J.; Park, S. J.; Teh, D. B.; Choi, Y.; Chang, Y. T.; All, A. H.; Yang, Y.; Xing, B.; Liu, X. Adv. Mater. 2017, 29, 1700244.

1. [A new approach for turn-on fluorescence sensing of L-DOPA](https://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc07640a#!divAbstract), Wang, L.; Su, D.; Berry, S. N.; Lee, J.; Chang, Y. T.* Chem. Commun. 2017, 53, 12465-12468.

1. [A Diversity-Oriented Library of Fluorophore-Modified Receptors Constructed from a Chemical Library of Synthetic Fluorophores](https://onlinelibrary.wiley.com/doi/full/10.1002/cbic.201700403), Nakano, S.; Tamura, T.; Das, R. K.; Nakata, E.; Chang, Y. T.; Morii, T. ChemBioChem, 2017, 18, 2212-2216.

1. [A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues](https://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc05834a#!divAbstract), Jun, Y. W.; Sarkar, S.; Singha, S.; Reo, Y. J.; Kim, H. R.; Kim, J. J.; Chang, Y. T.*; Ahn, K. H.* Chem. Commun. 2017, 53, 10800-10803.

1. [Motion-induced change in emission (MICE) for developing fluorescent probes](https://pubs.rsc.org/en/content/articlelanding/2017/cs/c7cs00018a#!divAbstract), Su, D.; Teoh, C. L.; Wang, L.; Liu, X.; Chang, Y. T.* Chem. Soc. Rev. 2017, 46, 4833-4844.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/135859_XfOCeXvEGUJTSDKFNS?q=80&s=1280x180&t=outside&f=webp)

1. [Push-pull type meso-ester substituted BODIPY near-infrared dyes as contrast agents for photoacoustic imaging](https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob00965h#!divAbstract), Ni, Y.; Kannadorai, R. K.; Yu, S. W.; Chang, Y. T.; Wu, J. Org. Biomol. Chem. 2017, 15, 4531-4535.

1. [Optical visualisation of thermogenesis in stimulated single cell brown adipocytes](https://www.nature.com/articles/s41598-017-00291-9), Kriszt, R.; Arai, S.; Itoh, H.; Lee, M. H.; Goralczyk, A. G.; Ang, X. M.; Cypess, A. M.; White, A. P.; Shamsi, F.; Xue, R.; Lee, J. Y.; Lee, S. C.; Hou, Y.; Kitaguchi, T.; Sudhaharan, T.; Ishiwata, S.; Lane, E. B.; Chang, Y. T. Tseng, Y. H.; Suzuki, M.; Raghunath, M. Sci. Rep. 2017, 7, 1383.

1. [Gold nanoshell-mediated remote myotube activation](https://pubs.acs.org/doi/10.1021/acsnano.6b08202), Marino, A.; Arai, S.; Hou, Y.; Degl’Innocenti, A.; Cappello, V.; Mazzolai, B.; Chang, Y. T.; Mattoli, V.; Suzuki, M.; Ciofani, G. ACS Nano 2017, 11, 2494-2508.

1. [Real-time in vivo hepatotoxicity monitoring through chromophore-conjugated upconversion nanoprobes](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201612020), Peng, J.*; Samanta, A.; Zeng, X.; Han, S.; Wang, L.; Su, D.; Loong, D. T. B.; Kang, N. Y.; Park, S. J.; All, A. H.; Jiang, W.; Yuan, L.*; Liu, X.*; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2017, 56, 4165-4169.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/140053_6kuLCy9M92XipahiOV?q=80&s=1280x180&t=outside&f=webp)

1. [Two-photon dye cocktail for dual-color 3D imaging of pancreatic beta and alpha cells in live islets](https://pubs.acs.org/doi/full/10.1021/jacs.6b12122), Agrawalla, B. K.; Lee, H. W.; Phue, W. H.; Raju, A.; Kim, J. J.; Kim, H. M.; Kang, N. Y.*; Chang, Y. T.* J. Am. Chem. Soc. 2017, 139, 3480-3487.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/140127_jqwn7u9hdjkYZdKhCu?q=80&s=1280x180&t=outside&f=webp)

1. [The vital dye CDr10b labels the Zebrafish mid-intestine and lumen](https://pmc.ncbi.nlm.nih.gov/articles/PMC6155399/), Sander, V.; Patke, S.; Lee, J. Y.; Chang, Y. T.; Davidson, A. J. Molecules 2017, 22, 454.

1. [Development of a BODIPY-based fluorescent probe for imaging pathological tau aggregates in live cells](https://pubs.rsc.org/en/content/articlelanding/2017/cc/c6cc08826k#!divAbstract), Lim, S.; Haque, M. M.; Su, D.; Kim, D.; Lee, J. S.; Chang, Y. T.; Kim, Y. K. Chem. Commun. 2017, 53, 1607-1610.

1. [Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe](https://pubs.acs.org/doi/10.1021/jacs.6b10508), Cheng, D.; Pan, Y.; Wang, L.; Zeng, Z.; Yuan, L.; Zhang, X.; Chang, Y. T. J. Am. Chem. Soc. 2017, 139, 285-292.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/140726_Mv33pcUuvsyXzkbxeF?q=80&s=1280x180&t=outside&f=webp)

1. [Development of pH-responsive BODIPY probes for staining late endosome in live cells](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cplu.201600249), Miao, F.; Uchinomiya, S.; Ni, Y.; Chang, Y. T.*; Wu, J.* ChemPlusChem 2016, 81, 1209-1215.

1. [A Fluorescent Probe for Neural Stem/Progenitor Cells with High Differentiation Capability into Neurons](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.201600490), Kim, B.; Feng, S.; Yun, S. W.; Leong, C.; Satapathy, R.; Wan, S. Y.; Chang, Y. T.* ChemBioChem 2016, 17, 2118-2122.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/140852_n5hmL3kl8wvd6LnnQo?q=80&s=1280x180&t=outside&f=webp)

1. [Photodynamic approach for teratoma-free pluripotent stem cell therapy using CDy1 and visible light](https://pubs.acs.org/doi/10.1021/acscentsci.6b00099), Cho, S.; Kim, S. Y.; Park, S. J.; Song, N.; Kwon, H. Y.; Kang, N. Y.; Moon, S. H.; Chang, Y. T._; Cha, H. J._ ACS Cent. Sci. 2016, 2, 604-607.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/140948_2hgodPFfyiSqQ4TsCF?q=80&s=1280x180&t=outside&f=webp)

1. [Specific Triazine Herbicides Induce Amyloid-b42 Production](https://journals.sagepub.com/doi/10.3233/JAD-160310), Portelius, E.; Durieu, E.; Bodinb, M.; Cam, M.; Pannee, J.; Charlotte Leuxe, Mabondzo, A.; Oumata, N.; Galons, H.; Lee, J. Y.; Chang, Y. T.; Stueber, K.; Koch, P.; Fontaine, G.; Potier, M.; Manousopoulou, A.; Garbis, S.; Covaci, A.; Van Dam, D.; De Deyn, P.; Karg, F.; Flajolet, M.; Omori, C.; Hata, S.; Suzuki, T.; Blennow, K.; Zetterberg, H.; Meijer, L. J. Alzheimer’s Dis. 2016, 54, 1593-1605.

1. [Naphthalene-fused BODIPY near-infrared dye as a stable contrast agent for in vivo photoacoustic imaging](https://pubs.rsc.org/en/content/articlelanding/2016/cc/c6cc05126j#!divAbstract), Ni, Y.; Kannadorai, R. K.; Peng, J.; Yu, S. W. K.; Chang, Y. T.*; Wu, J.* Chem. Commun. 2016, 52, 11504-11507.

1. [A Simple BODIPY-based viscosity probe for imaging of cellular viscosity in live cells](https://www.mdpi.com/1424-8220/16/9/1397), Su, D.; Teoh, C. L.; Gao, N.; Xu, Q. H.; Chang, Y. T.* Sensors 2016, 16, 1397.

1. [Discerning the chemistry in individual organelles with small molecule fluorescent probes](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201510721), Xu, W.; Zeng, Z.; Jiang, J. H.*; Chang, Y. T.*; Yuan, L.* Angew. Chem., Int. Ed. Engl. 2016, 55, 13658-13699.

1. [CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer](https://www.oncotarget.com/article/10528/), Roy, R.; Hoppe, M.; Sharma, N.; Srivastava, S.; Tan, K. T.; Yang, H.; Voon, D.; Pang, B.; Teh, M.; Murata-Kamiya, N.; Hatakeyama, M.; Samanta, A.; Chang, Y. T.; Ho, K. Y.; Ito, Y.; Tan, P.; Soong, R.; Koeffler, H.; Yeoh, K.; Jeyasekharan, A. Oncotarget 2016, 7, 55290-55301.

1. [Boronic acid: a bio-inspired strategy to increase the sensitivity and selectivity of fluorescent NADH probe](https://pubs.acs.org/doi/10.1021/jacs.6b05810), Wang, L; Zhang, J.; Kim, B.; Peng, J.; Berry, S. N.; Ni, Y.; Su, D.; Lee, J.; Yuan, L.; Chang, Y. T.* J. Am. Chem. Soc. 2016, 138, 10394-10397.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/141245_lcgNSxEFYMC507C72r?q=80&s=1280x180&t=outside&f=webp)

1. [Development of background-free tame fluorescent probes for intracellular live cell imaging](https://www.nature.com/articles/ncomms11964), Alamudi, S. H.; Satapathy, R.; Kim, J.; Su, D.; Ren, H.; Das, R.; Hu, L.; Alvarado-Martínez, E.; Lee, J. Y.; Hoppmann, C.; Peña-Cabrera, E.; Ha, H. H.; Park, H. S.*; Wang, L.*; Chang, Y. T.* Nat. Commun. 2016, 7, 11964.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/141231_p5DVWz5m9mi63Tb7uB?q=80&s=1280x180&t=outside&f=webp)

1. [Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells](https://pubs.rsc.org/en/content/articlelanding/2016/sc/c6sc01643j#!divAbstract), Berry, S. N.; Soto-Cerrato, V.; Howe, E. N. W.; Clarke, H. J.; Mistry, I.; Tavassoli, A.; Chang, Y. T.; Pérez-Tomás, R.; Gale, P. A. Chem. Sci. 2016, 7, 5069-5077.

1. [Prediction of intracellular localization of fluorescent dyes using QSAR models, Uchinomiya](https://www.eurekaselect.com/article/74867), S.; Horobin, R. W.; Alvarado-Martínez, E.; Peña-Cabrera, E._; Chang, Y. T._ Comb. Chem. High Throughput Screening 2016, 19, 378-383.

1. [Quantitative Measurement of Caffeine by Optical Methods](https://www.sciencedirect.com/science/article/abs/pii/B9780128006344000810), Xu, W.; Chang, Y. T.* in volume 3 of Neuropathology of Drug Addictions and Substance Misuse. pp 815-826, 2016.

1. [Detection of GHB by optical methods](https://www.sciencedirect.com/science/article/abs/pii/B9780128002124000492), Xu, W.; Zhai, D.; Chang, Y. T.* in volume 2 of Neuropathology of Drug Addictions and Substance Misuse. pp 529-535, 2016.

1. [RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming](https://www.sciencedirect.com/science/article/pii/S2211124716306477?via%253Dihub), Toh, C. X.; Chan, J. W.; Chong, Z. S.; Wang, H. F.; Guo, H. C.; Satapathy, S.; Ma, D.; Goh, G. Y.; Khattar, E.; Yang, L.; Tergaonkar, V.; Chang, Y. T.; Collins, J. J.; Daley, G. Q.; Wee, K. B.; Farran, C. A.; Li, H.; Lim, Y. P.; Bard, F. A.; Loh, Y. H. Cell Rep. 2016, 15, 2597-2607.

1. [A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase](https://pubs.rsc.org/en/content/articlelanding/2016/cc/c6cc00095a#!divAbstract), Zhang, L.; Er, J. C.; Jiang, H.; Li, X.; Luo, Z.; Ramezani, T.; Feng, Y.; Tang, M. K.; Chang, Y. T.; Vendrell, M. Chem. Commun. 2016, 52, 9093-9098.

1. [Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis](https://pubs.rsc.org/en/content/articlelanding/2016/cc/c6cc00439c#!divAbstract), Li, X.; Jiang, H.; Luo, Z.; Chang, Y. T.; Zhang, L. Chem. Commun. 2016, 52, 9086-9088.

1. [Direct organelle thermometry with fluorescence lifetime imaging microscopy in single myotubes](https://pubs.rsc.org/en/content/articlelanding/2016/cc/c5cc09943a#!divAbstract), Itoh, H.; Arai, S.; Sudhaharan, T.; Lee, S. C.; Chang, Y. T.; Ishiwata, S.; Suzuki, M.; Lane, E. B. Chem. Commun. 2016, 52, 4458-4461.

1. [Diradical Approach towards BODIPY Based Near-infrared Dyes with Intense Absorption around 1100 nm](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201511151), Ni, Y.; Lee, S.; Son, M.; Aratani, N.; Ishida, M.; Samanta, A.; Yamada, H.; Chang, Y. T.; Furuta, H.; Kim, D.; Wu, J. Angew. Chem., Int. Ed. Engl. 2016, 55, 2815-2819.

1. [Multisite-binding switchable fluorescent probe for monitoring mitochondrial ATP level fluctuation in live cells](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201510003), Wang, L.; Yuan, L.; Zeng, X.; Peng, J.; Ni, Y.; Er, J. C.; Xu, W. Agrawalla, B. K.; Su, D.; Kim, B.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2016, 55, 1773-1776.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/141958_9DtSMXUpOHnlJlLH1i?q=80&s=1280x180&t=outside&f=webp)

1. [Detection of pathogenic biofilms with bacterial amyloid targeting fluorescent probe](https://pubs.acs.org/doi/10.1021/jacs.5b11357), CDy11, Kim, J. Y.; Sahu, S.; Yau, Y. H.; Wang, X.; Shochat, S. G.; Nielsen, P. H.; Dueholm, M. S.; Otzen, D. E.; Lee, J.; Delos Santos, M. M.; Yam, J. K.; Kang, N. Y.; Park, S. J.; Kwon, H.; Seviour, T. W.; Yang, L.; Givskov, M.; Chang, Y. T.* J. Am. Chem. Soc. 2016, 138, 402-407.

![Image](https://upload.cafenono.com/image/slashpageHome/20250522/142016_GWg2fVqQHmfU1ocXGA?q=80&s=1280x180&t=outside&f=webp)

1. [Development of a highly selective, sensitive and fast response upconversion luminescent platform for hydrogen sulfide detection](https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adfm.201503715), Peng, J.; Teoh, C. L.; Zeng, X.; Samanta, A.; Wang, L.; Xu, W.;  Su, D.; Yuan, L._, Liu, X.; Chang, Y. T._ Adv. Funct. Mat. 2016, 26, 191-199.

1. [Axon-First Neuritogenesis on Vertical Nanowires](https://pubs.acs.org/doi/full/10.1021/acs.nanolett.5b04458), Kang, K.; Park, Y. S.; Park, M.; Jang, M. J.; Kim, S. M.; Lee, J.; Choi, J. Y.; Jung, D. H.; Chang, Y. T.; Yoon, M. H.; Lee, J. S.; Nam, Y.; Choi, I. S. Nano Lett. 2016, 16, 675-680.

1. [Thermosensitive nanoplatforms for photothermal release of cargo from liposomes under intracellular temperature monitoring](https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra19729e#!divAbstract), Arai, S.; Lee, C. L. K. ; Chang, Y. T.; Satoe, H.; Sou, K. RSC Adv. 2015, 5, 93530-93538.

1. [Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cells](https://pubs.rsc.org/en/content/articlelanding/2015/MB/C5MB00525F#!divAbstract), Kim, E. S; Samanta, A.; Cheng, H. S; Ding, Z.; Han, W.; Toschi, L.; Chang, Y. T.* Mol. Biosyst. 2015, 11, 3378-3386.

1. [Chemical Fluorescent Probe for Detection of Aβ Oligomers](https://pubs.acs.org/doi/10.1021/jacs.5b06190), Teoh, C. L.; Su, D.; Sahu, S.; Yun, S. W.; Drummond, E.; Prelli, F.; Lim, S.; Cho, S.; Ham, S._; Wisniewski, T._; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 13503-13509. Spotlights on Recent JACS Publications at J. Am . Chem. Soc. 2015, 137, 10017. ([http://pubs.acs.org/doi/pdf/10.1021/jacs.5b08475](http://pubs.acs.org/doi/pdf/10.1021/jacs.5b08475))

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/092727_pwFFKIBGMPcHNcRyRL?q=80&s=1280x180&t=outside&f=webp)

1. [A highly selective fluorescent probe for direct detection and isolation of mouse embryonic stem cells](https://www.sciencedirect.com/science/article/pii/S0960894X15006307), Chandran, Y.; Kang, N. Y.; Park, S. J.; Husen, A. S.; Kim, J. Y.; Sahu, S.; Su, D.; Lee, J.; Vendrell, M._; Chang, Y. T._ Bioorg. Med. Chem. Lett. 2015, 25, 4862-4865.

1. [Identification of disulfide crosslinked tau dimer responsible for tau propagation](https://www.nature.com/articles/srep15231), Kim, D.; Lim, S.; Haque, M. M.; Ryoo, N.; Hong, H. S; Rhim, H.; Lee, D.E.; Chang, Y. T.; Lee, J. S.; Cheong, E.; Kim, D. J.; Kim, Y. K. Sci. Rep. 2015, 5, 15231.

1. [NeuO for Neuronal Labeling in Zebrafish](https://pmc.ncbi.nlm.nih.gov/articles/PMC6024405/), Teoh, C. L.; Er, J. C.; Mukherjee, P.; Chang, Y. T.* Tomography 2015, 1, 30-36.

1. [Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes](https://www.sciencedirect.com/science/article/abs/pii/S0009308415000675), Arora, P.; Kharkwal, S. S.; Ng, T. W.; Kunnath-Velayudhan, S.; Saini, N. K.; Johndrow, C. T.; Chang, Y. T.; Besra, G. S.; Porcelli, S. A. Chem. Phys. Lipids 2015, 191, 75-83.

1. [Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation](https://pubs.acs.org/doi/10.1021/acsnano.5b03162), Marino, A.; Arai, S.; Hou, Y.; Sinibaldi, E.; Pellegrino, M.; Chang, Y. T.; Mazzolai, B.; Mattoli, V.; Suzuki, M.; Ciofani, G. ACS Nano 2015, 9, 7678-7689.

1. [Voices of chemical biology](https://www.nature.com/articles/nchembio.1820), Bertozzi, C. R.; Stockwell, B. R.; Kubicek, S.; Dickinson, B. C.; Chang, C. J.; Schultz, C.; Silver, P. A.; Gestwicki, J. E.; Chiosis, G.; Chattopadhyay, A.; Butcher, R. A.; Park, S. B.; Shoichet, B. K.; Flitsch, S.; Zhang, J.; Liu, D. R.; Ohnishi, Y.; Weerapana, E.; Williams, A. H.; He, C.; Moroni, A.; Thiel, G.; Chang, Y. T.; Waldmann, H.; Bogyo, M.; Oddershede, L. B.; Christopoulos, A.; Imperiali, B.; Ehrlich, H.; Chen, X.; Prescher, J. A. Nat. Chem. Biol. 2015, 11, 378-379.

1. [Suppression of the TRIF-dependent signaling pathway of Toll-like receptor by CDr10b in RAW264.7 macrophages](https://www.sciencedirect.com/science/article/abs/pii/S1567576915002465?via%253Dihub), Gu, G. J.; Ahn, S. I.; Kim, J. S.; Hong, C. Y.; Lee, S. C.; Chang, Y. T.; Choi, T. H.; Kim, B. S.; Youn, H. S. Int. Immunopharmacol. 2015, 28, 29-33.

1. [A Mitochondria-Targeted Ratiometric Fluorescent Probe to Monitor Endogenously Generated Sulfur Dioxide Derivatives in Living Cells](https://www.sciencedirect.com/science/article/pii/S0142961215003166), Wang, X.; Chai, L. T.; Peng, J.; Su, D.; Yuan, L._;  Chang, Y. T._ Biomaterials 2015, 56, 1-9.

1. [Development of nucleus staining fluorescent probe for dynamic mitosis imaging in live cells](https://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc02295a#!divAbstract), Ghosh, K. K.; Jeong, Y. M.; Kang, N. Y.; Lee, J. Y.; Wan, S. Y.; Kim, J. Y.; Yoo, J.; Kim, D.; Kim, Y. K._; Chang, Y. T._ Chem. Commun. 2015, 51, 9336-9338.

1. [Development of Targetable Two-Photon Fluorescent Probes to Image Hypochlorous Acid in Mitochondria and Lysosome in Live Cell and Inflamed Mouse Model](https://pubs.acs.org/doi/10.1021/jacs.5b00042), Yuan, L.; Wang, L.; Agrawalla, B. K.; Park, S. J.; Zhu, H.; Sivaraman, B.; Peng, J.; Xu, Q. H.; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 5930-5938.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/093005_hblGOsggplP0acyVSM?q=80&s=1280x180&t=outside&f=webp)

1. [Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient](https://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc01088h#!divAbstract), Arai, S.; Suzuki, M.; Park, S. J.; Yoo, J. S.; Wang, L.; Kang, N. Y.; Ha, H. H.; Chang, Y. T.* Chem. Commun. 2015, 51, 8044-8047.

1. [Glucagon-secreting alpha cell selective two-photon fluorescent probe TP-α: for live pancreatic islet imaging](https://pubs.acs.org/doi/full/10.1021/ja5115776), Agrawalla, B. K.; Chandran, Y.; Phue, W. H.; Lee, S. C.; Jeong, Y. M.; Wan, S. Y.; Kang, N. Y._; Chang, Y. T._ J. Am. Chem. Soc. 2015, 137, 5355-5362.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/093044_RhILUkhsxeNxsjb0ZC?q=80&s=1280x180&t=outside&f=webp)

1. [New Targets of Molecular Imaging in Atherosclerosis: Prehension of Current Status,](https://www.jstage.jst.go.jp/article/analsci/31/4/31_245/_article) Park, S. J.; Kim, J. Y.; Teoh, C. L.; Kang, N. Y.; Chang, Y. T.* Anal. Sci. 2015, 31, 245-255.

1. [Development of fluorescent probes specific for parallel-stranded G-quadruplexes by a library approach](https://pubs.rsc.org/en/content/articlelanding/2015/CC/C5CC01601K#!divAbstract), Zhang, L.; Er, J. C.; Li, X.; Heng, J. J.; Samanta, A.; Chang, Y. T.; Lee, C. L. Chem. Commun. 2015, 51, 7386-7389.

1. [Diversity oriented approach for chemical biology](https://onlinelibrary.wiley.com/doi/full/10.1002/tcr.201402087), Lee, J. S.; Lee, J. W.; Kang, N.; Ha, H. H._; Chang, Y. T._ Chem. Rec. 2015, 15, 495-510.

1. [Solid-phase synthesis of combinatorial 2,4-disubstituted-1,3,5-triazine via amine nucleophilic reaction](https://onlinelibrary.wiley.com/doi/full/10.1002/bkcs.10091), Moon, S. W.; Ham, J.; Chang, Y. T.; Lee, J. W. Bull. Kor. Chem. Soc. 2015, 36, 435-438.

1. [Cell specific imaging probe development and biomedical applications](https://link.springer.com/chapter/10.1007/978-3-319-11776-8_51), Kang, N. Y.; Chang, Y. T.* in “5th International Conference on Biomedical Engineering in Vietnam”, pp 211-214, Eds. V. Van Toi and T. H. Lien Phung, Springer: Switzerland, 2015.

1. [Rootin, a compound that inhibits root development through modulating PIN-mediated auxin distribution](https://www.sciencedirect.com/science/article/abs/pii/S0168945215000199?via%253Dihub), Jeong, S.; Kim, J. Y.; Choi, H.; Kim, H.; Lee, I.; Soh, M. S.; Nam, H. G.; Chang, Y. T._; Lim, P. O._; Woo, H. R.* Plant Sci. 2015, 233, 116-126.

1. [The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications](https://pubs.rsc.org/en/content/articlelanding/2015/cc/c4cc08814j#!divAbstract), Su, D.; Teoh, C. L.; Samanta, A.; Kang, N. Y.; Park, S. J.; Chang, Y. T.* Chem. Commun. 2015, 51, 3989-3992.

1. [Synthesis and systematic evaluation of dark resonance energy transfer (DRET)-based library and its application in cell imaging](https://aces.onlinelibrary.wiley.com/doi/full/10.1002/asia.201403257), Su, D.; Teoh, C. L.; Kang, N. Y.; Yu, X.; Sahu, S.; Chang, Y. T.* Chem. Asian J. 2015, 10, 581-585.

1. [CDy6, a photostable probe for long-term real-time visualization of mitosis and proliferating cells](https://www.sciencedirect.com/science/article/pii/S1074552114004530), Jeong, Y. M.; Duanting, Z.; Hennig, H.; Samanta, A.; Agrawalla, B. K.; Bray, M. A.; Carpenter, A. E.; Chang, Y. T.* Chem. Biol. 2015, 22, 299-307.

1. [New insight of squaraine-based biocompatible surface-enhanced Raman scattering nanotag for cancer-cell imaging](https://www.tandfonline.com/doi/abs/10.2217/nnm.14.125?rfr_dat=cr_pub%253Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%253Arid%253Acrossref.org&journalCode=nnm), Ramya, A.; Samanta, A.; Nisha, N.; Chang, Y. T.; Maiti, K. K. Nanomedicine 2015, 10, 561-571.

1. [NeuO: a fluorescent chemical probe for live neuron labeling](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201408614), Er, J. C.; Leong, C.; Teoh, C. L.; Yuan, Q.; Merchant, P.; Dunn, M.; Sulzer, D.; Sames, D.; Bhinge, A.; Kim, D.; Kim, S. M.; Yoon, M. H.; Stanton, L. W.; Je, S. H.; Yun, S. W._; Chang, Y. T._ Angew. Chem., Int. Ed. Engl. 2015, 54, 2442-2446. Highlighted at “A library of bright ideas, C&En News, 2015 (March 23), 93 (12), p 39-40”

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/093355_dMoH5gHGkCdpcIV5bX?q=80&s=1280x180&t=outside&f=webp)

1. [High-efficiency in vitro and in vivo detection of Zn2+ by dye-assembled upconversion nanoparticles](https://pubs.acs.org/doi/10.1021/ja5115248), Peng, J.; Xu, W.; Teoh, C. L.; Han, S.; Kim, B.; Samanta, A.; Er. J. C.; Wang, L.; Yuan, L.; Liu, X.; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 2336-2342.

1. [The small molecule probe PT-Yellow labels the renal proximal tubules in zebrafish](https://pubs.rsc.org/en/content/articlelanding/2015/CC/C4CC08075K#!divAbstract), Sander, V.; Patke, S. V.; Sahu, S.; Teoh, C. L.; Peng, P.; Chang, Y. T.; Davidson, A. J. Chem. Commun. 2015, 51, 395-398.

1. [Sensitive multiplex detection of serological liver cancer biomarkers using SERS active photonic crystal fiber probe](http://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201300084), Dinish, U. S; Balasundaram, G.; Chang, Y. T.; Olivo, M. J. Biophotonics 2014, 7, 956-965.

1. [Dark to light! A new strategy for large Stokes shift dyes: coupling of a dark donor with tunable high quantum yield acceptors](https://pubs.rsc.org/en/content/articlelanding/2014/sc/c4sc01821d#!divAbstract), Su, D. D.; Oh, J.; Lee, S. C.; Lim, J. M.; Sahu, S.; Yu, X.; Kim, D._; Chang, Y. T._ Chem. Sci. 2014, 5, 4812-4818.

1. [Chemical targeting of GAPDH moonlighting function in cancer cells reveals its role in tubulin regulation](https://www.sciencedirect.com/science/article/pii/S1074552114002993?via%253Dihub), Jung, D. W.; Kim, W. H.; Seo, S.; Oh, E.; Yim, S. H.; Ha, H. H.; Chang, Y. T.; Williams, D. R. Chem. Biol. 2014, 21, 1533-1545.

1. [Investigating fluorescent dyes in fluorescence-assisted screening](https://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc07008a#!divAbstract), Jee, J. E.; Lim, J.; Hyun, H.; Oon, J.; Ong, Y. S.; Massif, C.; Chang, Y. T.; Choi, H. S.; Lee, S. S. Chem. Commun. 2014, 50, 15220-15223.

1. [A molecular fluorescent probe for targeted visualization of temperature at the endoplasmic reticulum](https://www.nature.com/articles/srep06701), Arai, S.; Lee, S. C.; Zhai, D.; Suzuki, M.; Chang, Y. T.* Sci. Rep. 2014, 4, 6701.

1. [CDr10b inhibits the expression of cyclooxygenase-2 and inducible nitric oxide synthase induced by lipopolysaccharide](https://www.sciencedirect.com/science/article/abs/pii/S0014299914006414?via%253Dihub), Gu, G. J.; Lim, S. J.; Ahn, S. I.; Lee, S. C.; Chang, Y. T.; Choi, T. H.; Kim, B. S.; Eom, Y. B.; Lee, N. K.; Youn, H. S. Eur. J. Pharmacol. 2014, 742, 42-46.

1. [In Situ Investigation of Mammalian Inorganic Polyphosphate Localization Using Novel Selective Fluorescent Probes JC-D7 and JC-D8](https://pubs.acs.org/doi/10.1021/cb5000696), Angelova, P. R.; Agrawalla, B. K.; Elustondo, P. A.; Gordon, J.; Shiba, T.; Abramov, A. Y.; Chang, Y. T._; Pavlov, E. V._ ACS Chem Biol. 2014, 9, 2101-2110.

1. [An artificial tongue fluorescent sensor array for identification and quantitation of various heavy metal ions](https://pubs.acs.org/doi/10.1021/ac501953z), Xu, W.; Ren, C.; Teoh, C. L.; Peng, J.; Gadre, S. H.; Rhee, H. W._; Lee, C. L. K._; Chang, Y. T.* Anal. Chem. 2014, 86, 8763-8769.

1. [Inhibition of tau aggregation by a rosamine derivative that blocks tau intermolecular disulfide cross-linking](https://www.tandfonline.com/doi/abs/10.3109/13506129.2014.929103?journalCode=iamy20), Haque, M. M.; Kim, D.; Yu, Y. H.; Lim, S.; Kim, D. J.; Chang, Y. T.; Ha, H. H.; Kim, Y. K. Amyloid 2014, 21, 185-190.

1. [Milk quality control: instant and quantitative milk fat determination with a BODIPY sensor-based fluorescence detector](https://pubs.rsc.org/en/content/articlelanding/2014/CC/C4CC04670F#!divAbstract), Xu, W.; Bai, J.; Peng, J.; Samanta, A.; Divyanshu; Chang, Y. T.* Chem. Commun. 2014, 50, 10398-10401.

1. [In vivo detection of macrophage recruitment in hind-limb ischemia using a targeted near-infrared fluorophore](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103721), Yoo, J. S.; Das, R. K.; Jow, Z. Y.; Chang, Y. T.* PLoS One 2014, 9, e103721.

1. [A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation](https://pubs.rsc.org/en/content/articlelanding/2014/CC/C4CC02974G#!divAbstract), Yun, S. W.; Leong, C.; Bi, X.; Ha, H. H.; Yu, Y. H.; Tan, Y. L.; Narayanan, G.; Sankaran, S.; Kim, J. Y.; Hariharan, S.; Ahmed, S._; Chang, Y. T._ Chem. Commun. 2014, 50, 7492-7494.

1. [A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation](https://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc02038c#!divAbstract), Kang, N. Y.; Park, S. J.; Ang, X. W.; Samanta, A.; Driessen, W. H.; Ntziachristos, V.; Vasquez, K. O.; Peterson, J. D.; Yun, S. W._; Chang, Y. T._ Chem. Commun. 2014, 50, 6589-6591.

1. [Live cells imaging using a turn-on FRET-based BODIPY probe for biothiols](https://www.sciencedirect.com/science/article/pii/S0142961214004220), Su, D.; Teoh, C. L.; Sahu, S.; Das, R. K.; Chang, Y. T.* Biomaterials 2014, 35, 6078-6085.

1. [Biocompatible surface-enhanced Raman Scattering nanotags for in vivo cancer detection](https://www.tandfonline.com/doi/abs/10.2217/nnm.13.222?rfr_dat=cr_pub%253Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%253Arid%253Acrossref.org&journalCode=nnm), Samanta, A.; Jana, S.; Chang, Y. T.* Nanomedicine 2014, 9, 523-535.

1. [Multiplexing SERS nanotags for the imaging of differentiated mouse embryonic stem cells (mESC) and detection of teratoma in vivo](https://pmc.ncbi.nlm.nih.gov/articles/PMC3992207/), Samanta, A.; Das, R. K.; Park, S. J.; Maiti, K. K.; Chang, Y. T.* Am. J. Nucl. Med. Mol. Imaging 2014, 4, 114-124.

1. [A Chemical Probe that Lables Human Pluripotent Stem Cells](https://www.sciencedirect.com/science/article/pii/S2211124714000850?via%253Dihub), Hirata, N.; Nakagawa, M.; Fujibayashi, Y.; Yamauchi, K.; Murata, A.; Minami, I.; Tomioka, M.; Kondo, T.; Kuo, T. F.; Endo, H.; Inoue, H.; Sato, S. I.; Ando, S.; Kawazoe, Y.; Aiba, K.; Nagata, K.; Kawase, E.; Chang, Y. T.; Suemori, H.; Eto, K.; Nakauchi, H.; Yamanaka, S.; Nakatsuji, N.; Ueda, K.; Uesugi, M. Cell Rep. 2014, 6, 1165-1174.

1. [Mechanistic elements and critical factors of cellular reprogramming revealed by stepwise global gene expression analyses](https://www.sciencedirect.com/science/article/pii/S1873506114000294?via%253Dihub), Park, S. J.; Yeo, H. C.; Kang, N Y.; Kim, H. J.; Lin, J.; Ha, H. H.; Vendrell, M.; Lee, J. S.; Chandran, Y.; Lee, D. Y._; Yun, S. W._; Chang, Y. T.* Stem Cell Res. 2014, 12, 730-741.

1. [Diversity oriented fluorescence library approach (DOFLA) for live cell imaging probe development](https://pubs.acs.org/doi/10.1021/ar400285f), Yun, S. W.; Kang, N. Y.; Park, S. J.; Ha, H. H.; Kim, Y. K.; Lee, J. S.; Chang, Y. T.* Acc. Chem. Res. 2014, 47, 1277-1286.

1. [The role of “disaggregation” in optical probe development,](https://pubs.rsc.org/en/content/articlelanding/2014/CS/c3cs60368g#!divAbstract) Zhai, D.; Xu, W.; Zhang, L.; Chang, Y. T.* Chem. Soc. Rev. 2014, 43, 2402-2411.

1. [Wavelength and shape dependent SERS study to develop ultrasensitive nanotags for imaging of cancer cells](https://pubs.rsc.org/en/content/articlelanding/2014/RA/c3ra46208k#!divAbstract), Samanta, A.; Jana, S.; Das, R. K.; Chang, Y. T.* RSC Adv. 2014, 4, 12415-12421.

1. [“Orange Alert”: A fluorescent detector for bisphenol A in water environments](https://www.sciencedirect.com/science/article/pii/S0003267014001032?via%253Dihub), Zhang, L.; Er, J. C.; Xu, W.; Qin, X.; Samanta, A.; Jana, S.; Lee, C. L. K.; Chang, Y. T.* Anal. Chim. Acta 2014, 815, 51-56.

1. [meso-Ester and carboxylic acid substituted BODIPYs with far-red and near-infrared emission for bio-imaging applications](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.201303868), Ni, Y.; Zeng, L.; Kang, N. Y.; Huang, K. W.; Wang, L.; Zeng, Z.; Chang, Y. T._; Wu, J._ Chem. Eur. J. 2014, 20, 2301-2310.

1. [Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags,](https://www.nature.com/articles/srep04075) Dinish, U. S.; Balasundaram, G.; Chang, Y. T.; Olivo, M. Sci. Rep. 2014, 4, 4075.

1. [Discovery of a structural-element specific G-quadruplex “Light-Up” probe](https://www.nature.com/articles/srep03776), Zhang, L.; Er, J. C.; Ghosh, K. K.; Chung, W. J.; Yoo, J.; Xu, W.; Zhao, W.; Phan, A. T.; Chang, Y. T.* Sci. Rep. 2014, 4, 3776.

1. [Development of a fluorescent sensor for an illicit date rape drug-GHB](https://pubs.rsc.org/en/content/articlelanding/2014/CC/c3cc49603a#!divAbstract), Zhai, D.; Tan, Y. Q. E.; Xu, W.; Chang , Y. T.* Chem. Commun. 2014, 50, 2904-2906.

1. [A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens](https://www.sciencedirect.com/science/article/pii/S1074761313005542?via%253Dihub), Arora, P.; Baena, A.; Yu, K. O. A.; Saini, N. K.; Kharkwal, S. S.; Goldberg, M. F.; Kunnath-Velayudhan, S.; Carreño, L. J.; Venkataswamy, M. M.; Kim, J.; Lazar-Molnar, E.; Lauvau, G.; Chang, Y. T.; Liu, Z.; Bittman, R.; Al-Shamkhani, A.; Cox, L. R.; Jervis, P. J.; Veerapen, N.; Besra, G. S; Porcelli, S. Immunity, 2014, 40, 105-116.

1. [A macrophage-specific fluorescent probe for intraoperative lymph node staging](https://aacrjournals.org/cancerres/article/74/1/44/593891/A-Macrophage-Specific-Fluorescent-Probe-for), Yoo, J. S.; Lee, S. C.; Jow, Z. Y.; Koh, P. Y. X.; Chang, Y. T.* Cancer Res. 2014, 74, 44-55.

1. [Microglia specific fluorescent probe for live cell imaging](https://pubs.rsc.org/en/content/articlelanding/2014/cc/c3cc45715j#!divAbstract), Leong, C.; Lee, S. C.; Ock, J.; See, P.; Park, S. J.; Ginhoux, F.; Yun, S. W._; Chang, Y. T._ Chem. Commun. 2014, 50, 1089-1091.

1. [Ratiometric fluorescent probes for hydrogen peroxide from a focused library](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.201302523), Lee, H. W.; Rhee, H. W.; Chang, Y. T.; Hong J. I. Chem. Eur. J. 2013, 19, 14791-14794.

1. [Forward chemical genetic screening](https://link.springer.com/protocol/10.1007/978-1-62703-580-4_21), Choi, H.; Kim, J. Y.; Chang Y. T._; Nam, H. G._ Methods Mol. Biol. 2013, 1062, 393-404.

1. [Neural stem cell isolation from the whole mouse brain using the novel FABP7-binding fluorescent dye, CDr3](https://www.sciencedirect.com/science/article/pii/S1873506113001281), Leong, C.; Zhai, D.; Kim, B.; Yun, S. W._; Chang, Y. T._ Stem Cell Res. 2013, 11, 1314-1322.

1. [Focused fluorescent probe library for metal cations and biological anions](https://pubs.acs.org/doi/10.1021/co400034x), Rhee, H. W.; Lee, S. W.; Lee, J. S.; Chang, Y. T._; Hong, J. I._ ACS Comb. Sci. 2013, 15, 483-490.

1. [A fluorescent dye cocktail for multiplex drug-site mapping on human serum albumin](https://pubs.acs.org/doi/full/10.1021/co400060b), Er, J. C.; Vendrell, M.; Tang, M. K.; Zhai, D.; Chang, Y. T.* ACS Comb. Sci. 2013, 15, 452-457.

1. [Visualization and isolation of Langerhans islets by fluorescent probe PiY](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201302149), Kang, N. Y.; Lee, S. C.; Park, S. J.; Ha, H. H.; Yun, S. W.; Kostromina, E.; Gustavsson, N.; Ali, Y.; Chandran, Y.; Chun, H. S.; Bae, M. A.; Ahn, J. H.; Han, W.; Radda, G. K.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2013, 52, 8557-8560.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/094320_rWFGIgUDtq0rZuKpl9?q=80&s=1280x180&t=outside&f=webp)

1. [Make Caffeine visible: a fluorescent caffeine “traffic light” detector](https://www.nature.com/articles/srep02255), Xu, W.; Kim, T. H.; Zhai, D.; Er, J. C.; Zhang, L.; Kale, A. A.; Agrawalla, B. K.; Cho, Y. K.; Chang, Y. T.* Sci. Rep. 2013, 3, 2255.

1. [A ratiometric fluorescent dye for the detection of glutathione in live cell and liver cancer tissue](https://pubs.rsc.org/en/content/articlelanding/2013/CC/c3cc43480j#!divAbstract), Zhai, D.; Lee, S. C.; Yun, S. W.; Chang, Y. T.* Chem. Commun. 2013, 49, 7207-7209.

1. [Development of a chalcone-triazine fusion library: combination of a fluorophore and biophore](https://www.sciencedirect.com/science/article/pii/S004040391300556X), Lee, S. C.; Zhai, D.; Chang, Y. T.* Tetrahedron Lett. 2013, 54, 2976-2979.

1. [A unique small molecule inhibitor of enolase clarifies its role in fundamental biological processes](https://pubs.acs.org/doi/10.1021/cb300687k), Jung, D. W.; Kim, W. H.; Park, S. H.; Lee, J.; Kim, J.; Su, D.; Ha, H. H.; Chang, Y. T.; Williams, D. R. ACS Chem. Biol. 2013, 8, 1271-1282.

1. [The development of novel NIR tetraarylazadipyrromethene fluorescent dyes](https://www.mdpi.com/1996-1944/6/5/1779), Lee, S. C.; Zhai, D.; Mukherjee, P.; Chang, Y. T.* Materials 2013, 6, 1779-1788.

1. [Development of fluorescent sensor for illicit date rape drug-GBL](https://pubs.rsc.org/en/content/articlelanding/2014/cc/c3cc49603a#!divAbstract), Zhai, D.; Agrawalla, B. K.; Eng, E. S. F.; Lee, S. C.; Xu, W.; Chang, Y. T.* Chem. Commun. 2013, 49, 6170-6172.

1. [Discovery of a Chondroitin 4-Sulfate Fluorescent Probe](https://www.tandfonline.com/doi/abs/10.1080/10610278.2012.735670?journalCode=gsch20), Lee, S. C.; Zhai, D.; Chang, Y. T.* Supramol. Chem. 2013, 25, 41-45.

1. [Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1](https://pmc.ncbi.nlm.nih.gov/articles/PMC3608751/), Hawley, T. S.; Riz, I.; Yang, W.; Wakabayashi, Y.; DePalma, L.; Chang, Y. T.; Peng, W.; Zhu, J.; Hawley, R. G. Am. J. Hematol. 2013, 88, 265-272.

1. [MegaStokes BODIPY-Triazoles as Environmentally-Sensitive Turn-on Fluorescent Sensors](https://pubs.rsc.org/en/content/articlelanding/2013/sc/c3sc22166k#!divAbstract), Er, J. C.; Tang, M. K.; Chia, C. G.; Liew, H.; Vendrell, M._; Chang, Y. T._ Chem. Sci. 2013, 4, 2168-2176.

1. [Surface Enhanced Raman Scattering in Cancer Detection and Imaging](https://www.sciencedirect.com/science/article/pii/S0167779913000267), Vendrell, M.; Maiti, K. K.; Dhaliwal, K.; Chang, Y. T. Trends Biotechnol. 2013, 31, 249-257.

1. [Preparation and evaluation of BBB-permeable trehalose derivatives as potential therapeutic agents for Huntington’s disease](https://pubs.rsc.org/en/content/articlelanding/2013/md/c2md20112g#!divAbstract), Im, J. K.; Kim, S. J.; Jeong, Y. H.; Kim, W.; Lee, D. H.; Lee, W. S.; Chang, Y. T.; Kim, K. T.; Chung, S. K. MedChemComm 2013, 4, 310-316.

1. [Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors](https://www.sciencedirect.com/science/article/abs/pii/S0166354212002306?via%253Dihub), Takahashi, H.; Takahashi, C.; Moreland, N. J.; Chang, Y. T.; Sawasaki, T.; Ryo, A.; Vasudevan, S. G.; Suzuki, Y.; Yamamoto, N. Antivir. Res. 2012, 96, 305-314.

1. [Orally active desulfated low molecular weight heparin and deoxycholic acid conjugate, 6ODS-LHbD, suppresses neovascularization and bone destruction in arthritis](https://www.sciencedirect.com/science/article/pii/S0168365912007018), Hwang, S. R.; Seo, D. H.; Al-Hilal, T. A.; Jeon, O. C.; Kang, J. H.; Kim, S. H.; Kim, H. S.; Chang, Y. T.; Kang, Y. M.; Yang, V. C.; Byun, Y. J. Control. Release 2012, 163, 374-384.

1. [High-performance graphene-titania platform for detection of phosphopeptides in cancer cells](https://pubs.acs.org/doi/full/10.1021/ac301119r), Tang, L. A. L.; Wang, J.; Lim, T. K.; Bi, X.; Lee, W. C.; Lin, Q.; Chang, Y. T.; Lim, C. T.; Loh, K. P. Anal. Chem. 2012, 84, 6693-6700.

1. [A fluorescent screening platform for the rapid evaluation of chemicals in cellular reprogramming](https://www.sciencedirect.com/science/article/pii/S1873506112000669?via%253Dihub), Vendrell, M.; Park, S. J.; Chandran, Y.; Lee, C. L. K.; Ha, H. H.; Kang, N. Y.; Yun, S. W.; Chang, Y. T.* Stem Cell Res. 2012, 9, 185-191.

1. [Combinatorial strategies in fluorescent probe development](https://pubs.acs.org/doi/10.1021/cr200355j), Vendrell, M._; Zhai, D.; Er, J. C.; Chang, Y. T._ Chem. Rev. 2012, 112, 4391-4420.

1. [Eastern Staining: A simple recombinant protein detection technology using a small peptide tag and its orthogonal fluorescent compound](https://scienceon.kisti.re.kr/srch/selectPORSrchArticle.do?cn=JAKO201231434108161&SITE=CLICK), Lee, J. J.; Kim, J. Y.; Zhai, D.; Yun, S. W.; Chang, Y. T.* Interdiscip. Bio Central 2012, 4, article no. 5, doi: 10.4051/ibc.2012.3.2.0005.

1. [Combinatorial solid-phase synthesis of 4,6-diaryl and 4-aryl, 6-alkyl-1,3,5-triazines and their application to efficient biofuel production](https://pubs.acs.org/doi/10.1021/co300007a), Kim, J. Y. H.; Lee, J. W.; Lee, W. S.; Ha, H. H.; Vendrell, M.; Bork, J. T.; Lee, Y. S._; Chang, Y. T._ ACS Comb. Sci. 2012, 14, 395-398.

1. [Imaging Histamine in Live Basophils and Macrophages with a Fluorescent Mesoionic Acid Fluoride](https://pubs.rsc.org/en/content/articlelanding/2012/CC/c2cc32292g#!divAbstract), Kielland, N.; Vendrell, M.; Lavilla, R._; Chang, Y. T._ Chem. Commun. 2012, 48, 7401-7403.

1. [Neural -stem cell specific fluorescent chemical probe binding to FABP7](https://www.pnas.org/doi/10.1073/pnas.1200817109), Yun, S. W.; Leong, C. K. M; Zhai, D.; Tan, Y. L.; Lim, L.; Bi, X.; Lee, J. J.; Kim, H.; Kang, N. Y.; Ng, S. H.; Stanton, L. W.; Chang, Y. T.* Proc. Natl. Acad. Sci. USA 2012, 109, 10214-10217.

1. [A novel zebrafish human tumor xenograft model validated for anti-cancer drug screening](https://pubs.rsc.org/en/content/articlelanding/2012/MB/c2mb05501e#!divAbstract), Jung, D. W.; Oh, E. S.; Park, S. H.; Chang, Y. T.; Kim, C. H.; Choi, S. Y.; Williams, D. R. Mol. Biosyst. 2012, 8, 1930-1939.

1. [Development of fluorescent Chalcone library and its application in the discovery of a mouse embryonic stem cell probe](https://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc31662e#!divAbstract), Lee, S. C.; Kang, N. Y.; Park, S. J.; Yun, S. W.; Chandran, Y.; Chang, Y. T.* Chem. Commun. 2012, 48, 6681-6683.

1. [Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic wnt signaling](https://www.sciencedirect.com/science/article/pii/S0092867412004205?via%253Dihub), Speese, S. D.; Ashley, J.; Jokhi, V.; Nunnari, J.; Barria, R.; Li, Y.; Ataman, B.; Koon, A.; Chang, Y. T.; Li, Q.; Moore, M. J.; Budnik, V. Cell 2012, 149, 832-846.

1. [Multiplex Targeted in vivo Cancer Detection Using Sensitive Near-Infrared SERS Nanotags](https://www.sciencedirect.com/science/article/pii/S1748013212000266), Maiti, K. K.; Dinish, U. S.; Samanta, A.; Vendrell, M.; Soh, K. S.; Park, S. J.; Olivo, M.; Chang, Y. T.* Nano Today 2012, 7, 85-93.

1. [Bioimaging Probes Development by DOFLA (Diversity Oriented Fluorescence Library Approach) for in vitro, in vivo and clinical applications](https://link.springer.com/chapter/10.1007/978-3-642-25547-2_5), Yun, S. W.; Chang, Y. T.* in “Advances in Bio-Imaging: From Physics to Signal Understanding Issues”, pp 55-66, Eds. Loménie, Nicolas; Racoceanu, Daniel; Gouaillard, Alexandre, in State-of-the-Art and Challenges Series: Advances in Intelligent and Soft Computing, Vol. 120, Springer, 2012.

1. [Diversity Oriented Fluorescence Library Approach for Stem Cell Probe Development](https://link.springer.com/chapter/10.1007/978-94-007-2415-0_2), Yun, S. W.; Kang, N. Y.; Chang, Y. T.* in “Stem Cells and Cancer Stem Cells”, pp 7-14, Ed. Hayat, M. A., Therapeutic Applications in Disease and Injury, Vol. 3, Springer, 2012.

1. [Solid-phase synthesis of dyes and their application as sensors and bioimaging probes](https://onlinelibrary.wiley.com/doi/10.1002/9781118141649.ch14), Vendrell, M.; Ha, H. H.; Lee, S. C.; Chang, Y. T.* in “Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications”, pp 427-440, Eds. Toy P. and Lam Y., Wiley-WCH, 2012.

1. [Identification of cancer cell-line origins using fluorescence image-based phenomic screening](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032096), Lee, J. S.; Kim, Y. K.; Kim, H. J.; Hajar, S.; Tan, Y. L.; Kang, N. Y.; Ng, S. H.; Yoon, C. N.; Chang, Y. T.* PLoS One 2012, 7, e32096.

1. [Synthesis of a novel BODIPY library and its application in the discovery of a fructose sensor](https://pubs.acs.org/doi/full/10.1021/co200136b), Zhai, D.; Lee, S. C.; Vendrell, M.; Leong, L. P. Chang, Y. T.* ACS Comb. Sci. 2012, 14, 81-84.

1. [High content live cell imaging for the discovery of new antimalarial marine natural products](https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-12-1), Cervantes, S.; Stout, P. E.; Prudhomme, J.; Engel, S.; Bruton, M.; Cervantes, M.; Carter, D.; Chang, Y. T.; Hay, M. E.; Aalbersberg, W.; Kubanek, J.; Le Roch, K. G. BMC Infect. Dis. 2012, 12:1.

1. [Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028802), Nath, S.; Spencer, V. A.; Han, J.; Chang, H.; Zhang, K.; Fontenay, G. V.; Anderson, C.; Hyman, J. M.; Nilsen-Hamilton, M.; Chang, Y. T.; Parvin, B. PLoS One 2012, 7, e28802.

1. [Bioimaging of stem cells, live tissue and whole animals using Diversity Oriented Fluorescence Library Approach](https://link.springer.com/chapter/10.1007/978-1-4614-0601-3_38), Chang, Y. T.* in “The Primo Vascular System: Its Role in Cancer and Regeneration”, pp 285-289, Eds. K. S. Soh, K. A. Kang, and D. K. Harrison, Springer, 2012.

1. [A triazine compound S06 inhibits pro-invasive crosstalk between carcinoma cells and stromal fibroblasts via binding to heat shock protein 90](https://www.sciencedirect.com/science/article/pii/S1074552111003607?via%253Dihub), Jung, D. W.; Kim, J.; Che, Z. M.; Oh, E. S.; Eom, S. H.; Im, S. H.; Ha, H. H.; Chang, Y. T.; Williams, D. R.; Kim, J. Chem. Biol. 2011, 18, 1581-1590.

1. [Intracellular glutathione detection using MnO2-nanosheet modified upconversion nanoparticles](https://pubs.acs.org/doi/10.1021/ja2100774), Deng, R; Xie, X.; Vendrell, M.; Chang, Y. T.; Liu, X. J. Am. Chem. Soc. 2011, 133, 20168-20171.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/131848_hvCGr32h9rPuSPB7V1?q=80&s=1280x180&t=outside&f=webp)

1. [Diversity-oriented optical imaging probe development](https://www.sciencedirect.com/science/article/pii/S1367593111001542?via%253Dihub), Lee, J. S.; Vendrell, M.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2011, 15, 760-767.

1. [Styryl-based and Tricyclic Compounds as Potential Anti-Prion Agents](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024844), Chung, E.; Prelli, F.; Dealler, S.; Lee, W. S.; Chang, Y. T.; Wisniewski, T. PLoS One 2011, 6, e24844.

1. [Development of High Affinity Inhibitor of Prostaglandin Transporter PGT](https://jpet.aspetjournals.org/article/S0022-3565(24)46631-7/abstract), Chi, Y; Min, J.; Jasmin, J. F.; Lisanti, M. P.; Chang, Y. T.; Schuster, V. L. J. Pharmacol. Exp. Ther. 2011, 339, 633-641.

1. [Solid phase synthesis of ultra-photostable cyanine NIR dye library](https://pubs.rsc.org/en/content/articlelanding/2011/ra/c1ra00498k#!divAbstract), Da, R. K.; Samanta, A.; Ha, H. H.; Chang, Y. T.* RSC Adv. 2011, 1, 573-575.

1. [Combinatorial synthesis of galactosyl-1,3,5-triazines as novel nucleoside analogs](https://pubs.rsc.org/en/content/articlelanding/2011/OB/c1ob05733b#!divAbstract), Wang, S.; Chang, Y. T.* Org. Biomol. Chem. 2011, 9, 6924-6926.

1. [Solid-Phase Synthesis of BODIPY Dyes and Development of an Immunoglobulin Fluorescent Sensor](https://pubs.rsc.org/en/content/articlelanding/2011/MB/c1mb05137g#!divAbstract), Vendrell, M.; Krishna, G. G.; Ghosh, K. K.; Zhai, D.; Lee, J. S.; Zhu, Q.; Yau, Y. H.; Shochat, S. G.; Kim, H. R.; Chung, J.; Chang, Y. T.* Chem. Commun. 2011, 47, 8424-8426.

1. [Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain](https://pubs.rsc.org/en/content/articlelanding/2011/MB/c1mb05137g#!divAbstract), Kim, Y. K.; Lee, J. K.; Lee, J. S.; Yoon, C. N.; Chang, Y. T.* Mol. Biosyst. 2011, 7, 2375-2378.

1. [Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging](https://pubs.rsc.org/en/content/articlelanding/2011/CC/c1cc11253h#!divAbstract), Lee, J. H.; So, J. H.; Jeon, J. H.; Choi, E. B.; Lee, U. R.; Chang, Y. T.; Kim, C. H.; Bae, M. A.; Ahn, J. H. Chem. Commun. 2011, 47, 7500-7502.

1. [Synthesis and Characterization of a Cell-permeable Near-Infrared Fluorescent Deoxyglucose Analogue for Cancer Cell Imaging](https://pubs.rsc.org/en/content/articlehtml/2011/ob/c1ob05519d), Vendrell, M.; Samanta, A.; Yun, S. W.; Chang, Y. T.* Org. Biomol. Chem. 2011, 9, 4760-4762.

1. [Ultrasensitive Near-Infrared Raman Reporters for SERS-based in vivo Cancer Detection](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201007841), Samanta, A.; Maiti, K. K.; Soh, K. S.; Liao, X.; Vendrell, M.; Dinish, U. S.; Yun, S. W.; Bhuvaneswari, R.; Kim, H.; Rautela, S.; Chung, J.; Olivo, M.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2011, 50, 6089-6092.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/131915_gYyQJa4nYwUDcfd70d?q=80&s=1280x180&t=outside&f=webp)

1. [Solid phase combinatorial synthesis of xanthone library using click chemistry and its application to embryonic stem cell probe](https://pubs.rsc.org/en/content/articlelanding/2011/cc/c1cc11962a#!divAbstract), Ghosh, K. K; Ha, H. H.; Kang, N. Y.; Chandran, Y.; Chang, Y. T.* Chem. Commun. 2011, 47, 7488-7490.

1. [Development of Intravascular Contrast Agents for MRI Using Gadolinium Chelates](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.201100066), Kittigowittana, K.; Yang, C. T.; Cheah, W. C.; Chuang, K. H.; Tuang, C. Y.; Chang, Y. T.; Golay, X.; Bates, R. W. ChemMedChem 2011, 781-787.

1. [Diversity-driven chemical probe development for biomolecules: beyond hypothesis-driven approach](https://pubs.rsc.org/en/content/articlelanding/2011/CS/c0cs00172d#!divAbstract), Kang, N. Y.; Ha, H. H.; Yun, S. W.; Yu, Y. H.; Chang, Y. T.* Chem. Soc. Rev. 2011, 40, 3613-3626.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/131935_vL5wow4QXqdQ9YJC67?q=80&s=1280x180&t=outside&f=webp)

1. [Embryonic and induced pluripotent stem cell staining and sorting using live cell fluorescence imaging probe CDy1](https://www.nature.com/articles/nprot.2011.350), Kang, N. Y.; Yun, S. W.; Ha, H. H.; Park, S. J.; Chang, Y. T.* Nat. Protoc. 2011, 6, 1044-1052.

1. [Recapture of GFP Chromophore Fluorescence in a Protein Host](https://pubs.acs.org/doi/full/10.1021/co200025e), Baldridge, A.; Feng, S.; Chang, Y. T.; Tolbert, L. ACS Comb. Sci. 2011, 13, 214-217.

1. [A Photostable Near-Infrared Protein Labeling Dye for in vivo Imaging](https://aces.onlinelibrary.wiley.com/doi/full/10.1002/asia.201100041), Samanta, A.;  Vendrell, M.; Yun, S. W.; Guan, Z.; Xu, Q. H.; Chang, Y. T.* Chem. Asian J. 2011, 6, 1353-1357.

1. [A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids](https://pubs.acs.org/doi/10.1021/ja200070u), Arora, Pooja; Venkataswamy, Manjunatha; Baena, Andres; Bricard, Gabriel; Li, Qian; Veerapen, N.; Ndonye, R.; Park, J. J.; Lee, J. H.; Seo, K. C.; Howell, A.; Chang, Y. T.; Illarionov, P.; Besra, G.; Chung, S. K.; Porcelli, S. J. Am. Chem. Soc. 2011, 133, 5198-5201.

1. [Combinatorial Solid-Phase Synthesis of 6-aryl-1,3,5-triazines via Suzuki Coupling](https://www.publish.csiro.au/CH/CH11034), Lee, J. W.; Ha, H. H.; Vendrell, M.; Bork, J. T.; Chang, Y. T.* Aust. J. Chem. 2011, 64, 540-544.

1. [Bodipy-diacrylate Imaging Probes for Targeted Proteins inside Live cells](https://pubs.rsc.org/en/content/articlelanding/2011/cc/c1cc10362h#!divAbstract), Lee, J. J; Lee, S. C.; Zhai, D.; Ahn, Y. H.; Yeo, H. Y.; Tan, Y. L.; Chang, Y. T.* Chem. Commun. 2011, 47, 4508-4510.

1. [A colorimetric pH indicators and boronic acids ensemble array for quantitative sugar analysis](https://pubs.rsc.org/en/content/articlelanding/2011/cc/c0cc04616g#!divAbstract), Ghosh, K. K.; Yap, E.; Kim, H. J.; Lee, J. S.; Chang, Y. T.* Chem. Commun. 2011, 47, 4001-4003.

1. [Binding of fluorophores to proteins depends on the cellular environment](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201007626), Kim, Y. K.; Lee, J. S.; Bi, X.; Ha, H. H.; Ng, S. H.; Ahn, Y. H.; Lee, J. J.; Wagner, B. K.; Clemons, P. A.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2011, 50, 2761-2763.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/132803_lQSZjrBtpj01Xbu691?q=80&s=1280x180&t=outside&f=webp)

1. [Fluorescent labelling of membrane proteins on the surface of living cells by a self-catalytic glutathione S-transferase omega 1 tag](https://pubs.rsc.org/en/content/articlelanding/2011/MB/c0mb00327a#!divAbstract), Lee, J. J.; Son, J.; Ha, H. H.; Chang, Y. T.* Mol. Biosyst. 2011, 7, 1270-1276.

1. [Target Identification: A Challenging Step in Forward Chemical Genetics](https://www.semanticscholar.org/paper/Target-Identification%253A-A-Challenging-Step-in-Das-Samanta/f5dfd6f165e2a8633c40f3d41b0d91a2b616e146), Das, R. K.; Samanta, A.; Ghosh, K.; Zhai, D.; Xu, W.; Su, D.; Leong, C.; Chang, Y. T.* Interdiscip. Bio Central 2011, 3, article no. 3, doi: 10.4051/ibc.2011.3.1.0003.

1. [Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters](https://pubs.rsc.org/en/content/articlelanding/2011/cc/c0cc05265e#!divAbstract), Maiti, K. K.; Samanta, A.; Vendrell, M.; Soh, K. S.; Olivo, M.; Chang, Y. T.* Chem. Commun. 2011, 47, 3514-3516.

1. [Fluorescence response profiling for small molecule sensors utilizing the green fluorescent protein chromophore and its derivatives](https://pubs.acs.org/doi/10.1021/co100012k), Lee, J. S.; Baldridge, A.; Feng, S.; Yang, S. Q.; Kim, Y. K.; Tolbert, L. M.; Chang, Y. T.* ACS Comb. Sci. 2011, 13, 32-38.

1. [Combinatorial search of sensors](https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118019580.ch6), Vendrell, M.; Feng, S.; Chang, Y. T.* in “Chemosensors: Principles, Strategies and Application”, pp 87-106, Ed. B. Wang and E. V. Anslyn, John Wiley and Sons, 2011.

1. [Novel use of fluorescent glucose analogues to identify a new class of triazine-based insulin mimetics possessing useful secondary effects](https://pubs.rsc.org/en/content/articlelanding/2011/MB/C0MB00089B#!divAbstract), Jung, D. W.; Ha, H. H.; Zheng, X.; Chang, Y. T.; Williams, D. R. Mol. Biosyst. 2011, 7, 346-358.

1. [Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library](https://pubs.rsc.org/en/content/articlelanding/2011/CC/C0CC04495D#!divAbstract), Lee, J. S.; Kim, H. K.; Feng S.; Vendrell, M.; Chang, Y. T.* Chem. Commun. 2011, 47, 2339-2341.

1. [Quantitative structure-fluorescence property relationship analysis of a large BODIPY library](https://onlinelibrary.wiley.com/doi/full/10.1002/minf.201000089), Schueller, A.; Goh, G. B.; Kim, H.; Lee, J. S.; Chang, Y. T.* Mol. Inf. 2010, 29, 717-729.

1. [a-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014374), Bricard, G.; Venkataswamy, M. M.; Yu, K. O. A.; Im, J. S.; Ndonye, R. M.; Howell, A. R.; Veerapen, N.; Illarionov, P. A.; Besra, G. S.; Li, Q.; Chang, Y. T.; Porcelli, S. A. PLoS One 2010, 5, e14374.

1. [Development of photostable near-IR cyanine dyes](https://pubs.rsc.org/en/content/articlelanding/2010/cc/c0cc02366c#!divAbstract), Samanta, A.; Vendrell, M.; Das, R.;  Chang, Y. T.* Chem. Commun. 2010, 46, 7406-7408.

1. [Development of biocompatible SERS nanotag with increased stability by chemisorptions of reporter molecule for in vivo cancer detection](https://www.sciencedirect.com/science/article/pii/S0956566310004987?via%253Dihub), Maiti, K. K.; Dinish, U. S.; Fu, C. Y.; Lee, J. J.; Soh, K. S.; Yun, S. W.; Bhuvanaeswari, R.; Olivo, M._; Chang, Y. T._ Biosens. Bioelectron., 2010, 26, 398-403.

1. [A fluorescent rosamine compound selectively stains pluripotent stem cells](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201002463), Im, C. N.; Kang, N. Y.; Ha, H. H.; Bi, X.; Lee, J. J.; Park, S. J.; Lee, S. Y.; Vendrell, M.; Kim, Y. K.; Lee, J. S.; Li, J.; Ahn, Y. H.; Feng, B.; Ng, H. H.; Yun, S. W._; Chang, Y. T._ Angew. Chem., Int. Ed. Engl., 2010, 49, 7497-7500. Highlighted at “Fluorescence method detects stem cells, C&En News, 2010 (September 20), 88 (38), p 25”

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/133816_VQY7ahBn7nPIqpnr6T?q=80&s=1280x180&t=outside&f=webp)

1. [Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques](https://www.sciencedirect.com/science/article/pii/S0968089610005729), Hong, M. C.; Kim, Y. K.; Choi, J. Y.; Yang, S. Q.; Rhee, H.; Ryu, Y. H.; Choi, T. H.; Cheon, G. J; An, G. I.; Kim, H. Y.; Kim, Y.; Kim, D. J.; Lee, J. S.; Chang, Y. T._; Lee, K. C._ Bioorg. Med. Chem. 2010, 18, 7724-7730.

1. [Imaging metabolic syndrome](https://www.embopress.org/doi/full/10.1002/emmm.201000074), Han, W. P.; Chuang, K. H.; Chang, Y. T.; Olivo, M.; Velan, S. S.; Bhakoo, K.; Townsend, D.; Radda, G. K. EMBO Mol. Med. 2010, 2, 196-210.

1. [Anti-amyloidogenic effect of AA3E2 attenuates beta-amyloid induced toxicity in SK-N-MC cells](https://www.sciencedirect.com/science/article/abs/pii/S000927971000205X?via%253Dihub), Shaykhalishahi, H.; Taghizadeh, M.; Yazdanparast, R.; Chang, Y. T. Chem. Biol. Interact. 2010, 186, 16-23.

1. [A chemical screen identifies novel compounds that overcome glial-mediated inhibition of neuronal regeneration](https://www.jneurosci.org/content/30/13/4693), Usher, L.; Johnstone, A.; Erturk, A.; Hu, Y.; Strikis, D.; Wanner, I.; Moorman, S.; Lee, J. W.; Min, J.; Ha, H. H.; Duan, Y.; Hoffman, S.; Goldberg, J.; Bradke, F.; Chang, Y. T.; Lemmon, V.; Bixby, J. J. Neurosci. 2010, 30, 4693-4706.

1. [Mitochondrial Affinity of Guanidine-rich Molecular Transporters Built on myo– and scyllo-Inositol Scaffolds: Stereochemistry Dependency](https://koreascience.or.kr/article/JAKO201004140972713.page), Ghosh, S. C.; Kim, B.; Im, J.; Lee, W. S., Im, C, N.; Chang, Y. T.; Kim, W.; Kim, K. T.; Chung, S. K. Bull. Korean Chem. Soc. 2010, 31, 3623-3631.

1. [Diversity-oriented Fluorescence Library Approaches for Probe Discovery and Development](https://www.sciencedirect.com/science/article/pii/S1367593110000256), Vendrell, M.; Lee, J. S.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2010, 14, 383-389.

1. [Discovery of Novel Zebrafish Neural Tracers by Organism-based Screening of Rosamine Library](https://pubs.rsc.org/en/content/articlelanding/2010/CC/b920432f#!divAbstract), Li, J.; Ha, H. H.; Guo, L.; Coomber, D.; Chang, Y. T.* Chem. Commun. 2010, 46, 2932-2934.

1. [Isozyme-Specific Fluorescent Inhibitor of Glutathione S-Transferase Omega1](https://pubs.acs.org/doi/10.1021/cb100007s)­, Son, J. H.; Lee, J. J.; Lee, J. S.; Schuller, A.; Chang, Y. T.* ACS Chem. Biol. 2010, 5, 449-453.

1. [Control of muscle differentiation by a mitochondria-targeted fluorophore](https://pubs.acs.org/doi/full/10.1021/ja906862g), Kim, Y. K.; Ha, H. H.; Lee, J. S.; Bi, X. Z.; Ahn, Y. H.; Hajar, S.; Lee, J. J.; Chang, Y. T.* J. Am. Chem. Soc. 2010, 132, 576-579.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/133837_UQGQqisZ1Ulfc1IrRA?q=80&s=1280x180&t=outside&f=webp)

1. [Combinatorial Synthesis of Triphenylmethine Library and Their Application in the Development of Surface Enhanced Raman Scattering (SERS) Probes](https://pubs.rsc.org/en/content/articlelanding/2010/CC/B921550F#!divAbstract), Cho, S. J.; Ahn, Y. H.; Maiti, K. K.; Dinish, U. S.; Fu, C. Y.; Thoniyot, P.; Olivo, M.; Chang, Y. T.* Chem. Commun. 2010, 46, 722-724.

1. [Discovery of a Green DNA Probe for Live-Cell Imaging](https://pubs.rsc.org/en/content/articlelanding/2010/cc/b916858c#!divAbstract), Feng, S.; Kim, Y. K.; Yang, Q.; Chang, Y. T.* Chem. Commun. 2010, 46, 436-438.

1. Forward chemical genetics, Chang, Y. T.* in “Wiley Encyclopedia of Chemical Biology”, vol 2, pp94-111, Ed. Tadhq P. Beqley, Hoboken, N.J: John Wiley & Sons, 2009.

1. [Functional profiling, identification and inhibition of plasmepsins in intraerythrocytic malaria parasites](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.200903747), Liu, K.; Shi, H.; Xiao, H.; Chong, A. G. L.; Bi, X.; Chang, Y. T.; Tan, K. Yada, R. Y.; Yao, S. Q. Angew. Chem., Int. Ed. Engl. 2009, 48, 8293-8297.

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1. [Inhibition of H2O2-induced neuroblastoma cell cytotoxicity by a triazine derivative, AA3E2](https://www.sciencedirect.com/science/article/abs/pii/S0014299909006098?via%253Dihub), Shaykhalishahi, H.; Yazdanparast, R.; Ha, H. H.; Chang, Y. T. Eur. J. Pharmacol. 2009, 622, 1-6.

1. [Synthesis and cellular uptake properties of guanidine-containing molecular transporters built on sucrose scaffold](https://pubs.rsc.org/en/content/articlelanding/2009/MB/b901846h#!divAbstract), Lee, W. S.; Im, C. N.; Teng, Q. Y.; Chang, Y. T.; Kim, D. C.; Kim, K. T.; Chung, S. K. Mol. Biosyst. 2009, 5, 822-825.

1. [Synthesis of a bodipy library and its application to the development of live cell glucagon imaging probe](https://pubs.acs.org/doi/10.1021/ja9011657), Lee, J. S.; Kang, N. Y.; Kim, Y. K.; Samanta, A.; Feng, S.; Kim, H. K.; Vendrell, M.; Park, J. H.; Chang, Y. T.* J. Am. Chem. Soc. 2009, 131, 10077-10082. Highlighted at JACS Select #10: Supramolecular and Chemical Cascade Approaches to Molecular Sensing.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/133907_vQZxBaRMwVfvR5heUZ?q=80&s=1280x180&t=outside&f=webp)

1. [Colorimetric sensor array for qualitative water anslysis](https://www.publish.csiro.au/ch/CH09289), Chan, S. A.; Lee, J. S.; Chang Y. T.* Aust. J. Chem. 2009, 62, 1040-1046.

1. [Novel orthogonal synthesis of tagged combinatorial triazine library via Grignard reaction](https://www.publish.csiro.au/CH/CH09153), Lee, J. W.; Bork, J. T. Ha, H. H.; Samanta, A.; Chang, Y. T.* Aust. J. Chem. 2009, 62, 1000-1006.

1. [Diversity oriented fluorescence library approach for novel sensor development](https://link.springer.com/chapter/10.1007/978-0-387-73713-3_17), Wang, S.; Chang, Y. T.* in “Combinatorial methods for chemical and biological sensors”, pp 419-440, Eds. R. A. Potyrailo and V. M. Mirsky, Springer: New York, 2009.

1. [Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation](https://www.sciencedirect.com/science/article/pii/S1074761309002386?via%253Dihub), Im, J. S.; Arora, P.; Bricard, G.; Molano, A.; Baine, I.; Jerud, E. S.; Goldberg, M. F.; Yu, K. O. A.; Howell, A. R.; Chang, Y. T.; Illarionov, P. A.; Besra, G. S.; Porcelli, S. A. Immunity, 2009, 30, 888-898.

1. [High-content live cell imaging with RNA probes: advancements in high throughput antimalarial drug discovery](https://bmcmolcellbiol.biomedcentral.com/articles/10.1186/1471-2121-10-45), Cervantes, S.; Prudhomme, J.; Carter, D.; Krishna, G. G.; Li, Q.; Chang, Y. T., Le Roch, K. G. BMC Cell Biol. 2009, 10, 45.

1. [Diversity-Oriented Fluorescence Library Approach for Discovery of Sensors and Probe](https://pubs.rsc.org/en/content/articlelanding/2009/mb/b821766c#!divAbstract), Lee, J. S.; Kim, Y. K.; Vendrell, M.; Chang, Y. T.* Mol. Biosyst. 2009, 5, 411-421.

1. [Machine vision-assisted analysis of structure-localization relationships in a combinatorial library of prospective bioimaging probes](https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.a.20713), Shedden, K.; Li, Q.; Liu F.; Chang, Y. T.; Rosania, G. Cytometry A 2009, 75, 482-493.

1. [Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility](https://onlinelibrary.wiley.com/doi/full/10.1002/pro.33), Lee, L. L.; Ha, H.; Chang, Y. T.; DeLisa, M. P. Protein Sci. 2009, 18, 277-286.

1. [Evaluation of synthetic sphingolipid analogs as ligands for peroxisome proliferators-activated receptors](https://www.sciencedirect.com/science/article/pii/S0960894X09001462?via%253Dihub), Tsuji, K.; Satoh, S.; Mitsutake, S.; Murakami, I.; Park, J. J.; Li, Q.; Chang, Y. T.; Chung, S. K.; Igarashi, Y. Bioorg. Med. Chem. Lett. 2009, 19, 1643-1646.

1. [Tagged library for chemical genetics](https://hstalks.com/t/945/tagged-library-for-chemical-genetics/), Chang, Y. T.* in Austin, D. (ed.), Chemical Biology: The role of Chemistry in our fundamental understanding of Biology, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London, 2008.

1. [Diversity oriented fluorescence library approach (DOFLA) to the discovery of chymotrypsin sensor](https://pubs.acs.org/doi/full/10.1021/cc700189b), Wang, S.; Kim, Y. K.; Chang, Y. T.* J. Comb. Chem. 2008, 10, 460-465.

1. [Selective human serum albumin sensor from the screening of a fluorescent rosamine library](https://pubs.acs.org/doi/full/10.1021/cc800017h), Ahn, Y. H.; Lee, J. S.; Chang, Y. T.* J. Comb. Chem. 2008, 10, 376-380.

1. [Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents](https://www.sciencedirect.com/science/article/pii/S0960894X08000450?via%253Dihub), Zhou, C.; Min, J.; Liu, Z.; Young, A.; Deshazer, H.; Gao, T.; Chang, Y. T.; Kallenbach, N. R. Bioorg. Med. Chem. Lett. 2008, 18, 1308-1311.

1. [Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening](https://pubs.acs.org/doi/10.1021/ja077656d), Wagner, B. K.; Carrinski, H. A.; Ahn, Y. H.; Kim, Y. K.; Gilbert, T. J.; Fomina, D. A.; Schreiber, S. L.; Chang, Y. T.; Clemons, P. A. J. Am. Chem. Soc. 2008, 130, 4208-4209.

![Image](https://upload.cafenono.com/image/slashpageHome/20250602/133921_velkZYZN5NjazkpxMx?q=80&s=1280x180&t=outside&f=webp)

1. [Discovery of heparin chemosensors through diversity oriented fluorescence library approach](https://pubs.rsc.org/en/content/articlelanding/2008/cc/b717058k#!divAbstract), Wang, S.; Chang, Y. T.* Chem. Commun. 2008, 1173-1175. Highlighted at “Blood sensor for safer surgery, Chemical Biology (RSC), 2008 (January 10)”

1. [Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library](https://www.sciencedirect.com/science/article/abs/pii/S0045206807000910), Park, J. J.; Li, Q.; Diaz, K.; Chang, Y. T.; Chung, S. K. Bioorg. Chem. 2008, 36, 220-228.

1. [Synthesis and anticancer activity studies of cyclopamine derivatives](https://www.sciencedirect.com/science/article/pii/S0960894X08000218), Zhang, J.; Garrossian, M.; Gardner, D.; Garrossian, A.; Chang, Y. T.; Kim, Y. K.; Chang, C. W. T. Bioorg. Med. Chem. Lett. 2008, 18, 1359-1363.

1. [중심학문으로서의 화학: 생물화학](https://new.kcsnet.or.kr/pub_chemworld_ebook), Chang, Y. T.* 화학세계 2007, January, 24-31.

1. [Enhancing effects of ceramide derivatives on 1,25-dihydroxyvitamin D(3)-induced differentiation of human HL-60 leukemia cells](https://www.sciencedirect.com/science/article/abs/pii/S0024320507007692?via%253Dihub), Kim, D. S.; Kim, S. H.; Song, J. H.; Chang, Y. T.; Hwang, S. Y.; Kim, T. S. Life Sci. 2007, 81, 1638-1644.

1. [Investigations of the molecular mechanism of metal-induced abeta (1-40) amyloidogenesis](https://pubs.acs.org/doi/10.1021/bi701112z), Lim, K. H.; Kim, Y. K.; Chang, Y. T. Biochemistry 2007, 46, 13523-12532.

1. [Rapid identification of immunostimulatory a-galactosylceramides using synthetic combinatorial libraries](https://pubs.acs.org/doi/10.1021/cc070057i), Li, Q.; Ndonye, R. M.; Illarionov, P. A.; Yu, K. O. A.; Jerud, E. S.; Diaz, K.; Bricard, G.; Porcelli, S. A.; Besra, G. S.; Chang, Y. T.; Howell, A. R. J. Comb. Chem. 2007, 9, 1084-1093.

1. [Combinatorial dapoxyl dye library and its application to site selective probe for human serum albumin](https://pubs.acs.org/doi/full/10.1021/cc0700546), Min, J.; Lee, J. W.; Ahn, Y. H.; Chang, Y. T.* J. Comb. Chem. 2007, 9, 1079-1083.

1. [Counterion free colorimetic metal cation sensor array](https://pubs.acs.org/doi/full/10.1021/cc070065z), Lee, J. S.; Lee, J. W.; Chang, Y. T.* J. Comb. Chem. 2007, 9, 926-928.

1. [Styryl-based compounds as potential in vivo imaging agents for b-amyloid plaques](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.200700154), Li, Q.; Min, J.; Ahn, Y. H.; Namm, J.; Kim, E. M.; Lui, R.; Kim, H. Y.; Ji, Y.; Wu, H.; Wisniewski, T.; Chang, Y. T.* ChemBioChem 2007, 8, 1679-1687.

1. [Tagged small molecule library approach for facilitated chemical genetics](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.200700154), Ahn, Y. H.; Chang, Y. T.* Acc. Chem. Res. 2007, 40, 1025-1033.

1. [Tagged library approach facilitates forward chemical genetics](https://pubs.rsc.org/en/content/articlelanding/2007/MB/b702321a#!divAbstract), Kim, Y. K.; Chang, Y. T.* Mol. Biosyst. 2007, 3, 392-397.

1. [Combinatorial rosamine library and application to in vivo glutathione probe](https://pubs.acs.org/doi/full/10.1021/ja068230m), Ahn, Y. H.; Lee, J. S.; Chang, Y. T.* J. Am. Chem. Soc. 2007, 129, 4510-4511.

1. [Understanding activity of small molecules in the genomic context (Highlight article)](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.200604972), Lee, J. S.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2007, 46, 3616-3618.

1. [Small-molecule switch for zebrafish gene expression (News and Views)](https://www.nature.com/articles/nchembio0307-135), Chang, Y. T.*, Nat. Chem. Biol. 2007, 3, 135-136.

1. [Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part II. Integrase inhibition](https://www.sciencedirect.com/science/article/pii/S0006291X07000824), Lee-Huang, S.; Huang, P. L.; Zhang, D.; Lee, J. W.; Bao, J.; Sun, Y.; Chang, Y. T.; Zhang, J.; Huang, P. L. Biochem. Biophys. Res. Commun. 2007, 354, 879-884.

1. [Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition](https://www.sciencedirect.com/science/article/pii/S0006291X07000812), Lee-Huang, S.; Huang, P. L.; Zhang, D.; Lee, J. W.; Bao, J.; Sun, Y.; Chang, Y. T.; Zhang, J.; Huang, P. L. Biochem. Biophys. Res. Commun. 2007, 354, 872-878.

Identification of a novel protein regulating microtubule stability through a chemical approach

1. [Forward chemical genetic approach identifies new role for GAPDH in insulin signaling](https://www.nature.com/articles/nchembio833), Min, J. K.; Kim, Y. K.; Cipriani, P. G.; Kang, M.; Khersonsky, S. M.; Walsh, D. P.; Lee, J. Y.; Niessen, S.; Yates, J. R.; Gunsalus, K.; Piano, F.; Chang, Y. T.* Nat. Chem. Biol. 2007, 3, 55-59. Highlighted at “New diabetes target, C&En News, 2006 (December 4), 84 (49), p 63” & “NYU, Scripps Finding offers New Path For Treatment of Diabetes, Medical News Today, 2006 (November 30)”

1. [A protocol for preparing, characterizing and using three RNA-specific, live cell imaging probes: E36, E144 and F22](https://www.nature.com/articles/nprot.2006.484), Li, Q.; Chang, Y. T.* Nat. Protoc. 2006, 1, 2922-2932.

1. [Colorimetric identification of carbohydrates by a pH indicator/ pH change inducer ensemble](https://onlinelibrary.wiley.com/doi/10.1002/anie.200602055), Lee, J. W.; Lee, J. S.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2006, 45, 6485-6487. Highlighted at “Discriminating between carbohydrates, C&En News, 2006 (September 25), 84 (39), p 90”

1. [Myoseverin is a potential angiogenesis inhibitor by inhibiting endothelial cell function and endothelial progenitor cell differentiation](https://www.liebertpub.com/doi/abs/10.1089/dna.2006.25.514), Park, H. E.; Baek, S. H.; Min, J. K.; Chang, Y. T.; Kang, D. K.; Chang, S. I.; Joe, Y. A. DNA Cell Biol. 2006, 25, 514-522.

1. [A high throughput screen for compounds that inhibit aggregation of the Alzheimer’s peptide](https://pubs.acs.org/doi/10.1021/cb600135w), Kim, W.; Kim Y. K.; Min, J. K.; Kim, D. J.; Chang, Y. T._; Hecht, M. H._ ACS Chem. Biol. 2006, 1, 461-469. Previewed at “From green bacteria to human dementia: a novel model for discovering amyloid assembly inhibitors, Gazit, E. Chem. Biol. 2006, 1, 417-419.

1. [Combinatorial synthesis of benzimidazolium dyes and its diversity directed application toward GTP-selective fluorescent chemosensors](https://pubs.acs.org/doi/10.1021/ja063733d), Wang, S.; Chang, Y. T.* J. Am. Chem. Soc. 2006, 128, 10380-10381.

1. RNA-selective, live cell imaging probes for studying nuclear structure and function., Li, Q., Kim, Y. K., Namm, J., Kulkarni, A., Rosania, G., Ahn, Y. H., Chang, Y. T.* Chem. Biol. 2006, 13, 615-623.  Previewed at “Styryl molecules light-up RNAs, Dirks, R. W.; Tnake, H. J. Chem. Biol. 2006, 13, 560-561.” Highlighted at “Styryl dyes image RNA in living cells, Borman, S. C&En News, 2006 (July 3), 84 (27), p30” & at “RNA dyes for life, Rothman, S. The Scientist, 2006, 20, 67” & at “Illuminating cellular RNA, Sheppard, T. L. Nat. Chem. Biol. 2006, 2, 405” & at “Live and let dye, Biotechniques 2006, 41, 231”

1. [Visual artificial tongue for quantitative metal cation analysis by an off-the-shelf dye array](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.200600307), Lee, J. W.; Lee, J. S.; Kang, M.; Su, A. I.; Chang, Y. T.* Chem. Eur. J. 2006, 12, 5691-5696.

1. [Chemical Genetics](https://pubs.acs.org/doi/10.1021/cr0404141), Walsh, D. P.; Chang, Y. T.* Chem. Rev. 2006, 106, 2476-2530.

1. [Inhibition of interleukin-4 production in activated T cells via the downregulation of AP-1/NF-AT activation by N-lauroyl-d-erythro-sphingosine and N-lauroyl-d-erythro-C(20)-sphingosine](https://www.sciencedirect.com/science/article/pii/S0006295206000074), Park, J.; Kim, S. H.; Li, Q.; Chang, Y. T. Kim, T. S. Biochem. Pharmacol., 2006, 71, 1229-1239.

1. [Fce RI control of Ras via inositol (1,4,5) trisphosphate 3-kinase and inositol tetrakisphosphate](https://linkinghub.elsevier.com/retrieve/pii/S0898-6568(05)00137-3), Stokes, A. J.; Shimoda, L. M.; Lee. J. W.; Chang, Y. T.; Turner, H. Cell Signal. 2006, 18, 640-651.

1. [Identification of a new class of PGT inhibitors and characterization of their biological effects on PGE2 transport](https://jpet.aspetjournals.org/article/S0022-3565(24)32561-3/abstract), Chi, Y.; Khersonsky, S. M.; Chang, Y. T.; Schuster, V. L. J. Pharmacol. Exp. Ther. 2006, 316, 1346-1350.

1. [Identification of 12Cysb on tubulin as the binding site of tubulyzine](https://www.sciencedirect.com/science/article/pii/S0968089605009491?via%253Dihub), Kim, Y. J.; Sackett, D. L.; Schapira, M.; Walsh, D. P.; Min, J.; Pannell, L. K.; Chang, Y. T.* Bioorg. Med. Chem. 2006, 14, 1169-1675.

1. [Triazine-based tyrosinase inhibitors identified by chemical genetic screening](https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0749.2005.00273.x), Ni-Komatsu, L.; Leung, J. K.; Williams, D.; Min, J.; Khersonsky, S. M.; Chang, Y. T.; Orlow, S. J. Pigment Cell Res. 2005, 18, 447-453.

1. [Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression](https://www.sciencedirect.com/science/article/pii/S1550413105003414?via%253Dihub), Harding, H. P.; Zhang, Y.; Khersonsky, S.; Marciniak, S.; Javitt, N.; Chang, Y. T.; Ron, D. Cell Metab. 2005, 2, 361-371.

1. [A single cell analysis of myogenic dedifferentiation induced by small molecules](https://www.cell.com/cell-chemical-biology/comments/S1074-5521(05)00264-4), Duckmanton, A.; Kumar, A.; Chang, Y. T.; Brockes, J. P. Chem. Biol. 2005, 12, 1117-1126.

1. [Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish](https://pubs.rsc.org/en/content/articlelanding/2005/MB/b417765g#!divAbstract), Jung, D. W.; Williams, D. Khersonsky, S. M.; Kang, T. W.; Heidary, N.; Chang, Y. T.; Orlow, S. J. Mol. Biosyst. 2005, 1, 85-92.

1. Bookreview for “Methods in Pharmacology and Toxicology: Optimization in Drug Discovery: In Vitro Methods” by Zhengyun Yan and Cary W. Caldwell, Chang, Y. T. ChemBioChem 2005, 6, 1127-1130.

1. [Phytic Acid Synthesis and Vacuolar Accumulation in Suspension-Cultured Cells of Catharanthus roseus Induced by High Concentration of Inorganic Phosphate and Cations](http://www.plantphysiol.org/content/138/3/1607), Mitsuhashi, N.; Ohnishi, M.; Sekiguchi, Y.; Kwon, Y. U.; Chang, Y. T.; Chung, S. K.; Inoue, Y.; Reid, R. j.; Yagisawa, H.; Mimura, T. Plant Physiol. 2005, 138, 1607-1614.

1. [Dissection of melanogenesis with small molecules identifies prohibitin as a regulato](https://linkinghub.elsevier.com/retrieve/pii/S1074-5521(05)00073-6)r, Snyder, J. R.; Hall, A.; Ni-Komatsu, L.; Khersonsky, S. M.; Chang, Y. T.; Orlow, S. J. Chem. Biol. 2005, 12, 477-484. Highlighted at “Mitochondria give cells a tan, Rosania, G. R. Chem. Biol. 2005, 12, 412-413.”

1. [Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of a-galactosylceramides](https://www.pnas.org/doi/full/10.1073/pnas.0407488102), Yu, K. O. A.; Im, J. S.; Molano, A.; Dutronc, Y.; Illarionov, P. A.; Forestier, C.; Fujiwara, N.; Arias, I.; Miyake, S.; Yamamura, T.; Chang, Y. T.; Besra, G. S.; Porcelli, S. A.  Proc. Nat. Acad. Sci. U. S. A. 2005, 102, 3383-3388.

1. [Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity](https://pubs.acs.org/doi/10.1021/bi0477081), Lee-Huang, S.; Maiorov, V.; Huang, P. L.; Ng, A.; Lee, H. C.; Chang, Y. T.; Kallenbach, N.; Huang, P. L.; Chen, H. C. Biochemistry 2005, 44, 4648-4655.

1. [Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells](https://www.sciencedirect.com/science/article/pii/S0968089605000532), Park, J.; Li, Q.; Chang, Y. T.; Kim, T. S. Bioorg. Med. Chem. 2005, 13, 2589-2595.

1. [Small molecule microarrays: recent advances and applications](https://www.sciencedirect.com/science/article/pii/S1367593104001644?via%253Dihub), Uttamchandani, M.; Walsh, P. D.; Yao, S. Q.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2005, 9, 4-13.

1. [Solid phase synthesis of styryl dye library and its application to amyloid sensors](https://onlinelibrary.wiley.com/doi/full/10.1002/anie.200461600), Li, Q.; Lee, J. S.; Ha, C.; Park, C. B.; Yang G.; Gan, W. B.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2004, 43, 6331-6335.

1. [System dynamics of subcellular transport](https://pubs.acs.org/doi/full/10.1021/mp049916t), Chen, V. Y.; Khersonsky, S. M.; Shedden, K.; Chang, Y. T.; Rosania, G. R. Mol. Pharm. 2004, 1, 414-425.

1. [Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatases Schizosaccharomyces pombe synaptojanin and SHIP2](https://www.jbc.org/article/S0021-9258(19)70954-5/fulltext), Chi, Y.; Zhou, B.; Wang, W. Q.; Chung, S. K.; Kwon, Y. U.; Ahn, Y. H.; Chang, Y. T. Tsujishita, Y.; Hurley, J. H.; Zhang, Z. Y. J. Biol. Chem. 2004, 279, 44987-44995.

1. [Microarrays of Tagged Combinatorial Triazine Libraries in the Discovery of Small Molecule Ligands of Human IgG](https://pubs.acs.org/doi/10.1021/cc049900s), Uttamchandani, M.; Walsh, D. P.; Khersonsky, S. M.; Huang, X.; Yao, S. Q.; Chang, Y. T.* J. Comb. Chem. 2004, 6, 862-868.

1. [Identification of compounds that bind F1F0 ATPase by screening a triazine library for correction of albinism](https://www.sciencedirect.com/science/article/pii/S107455210400225X?via%253Dihub), Williams, D.; Jung, D. W.; Khersonsky, S. M.; Heidary, N.; Chang, Y. T.; Orlow, S. J. Chem. Biol. 2004, 11, 1251-1259.

1. [Recent Advances in Small Molecule Microarrays: Applications and Technology](https://www.eurekaselect.com/article/6792), Walsh, D. P.; Chang, Y. T.* Comb. Chem. High Throughput Screening 2004, 7, 557-564.

1. [The combinatorial synthesis of purine, pyrimidine, and triazine-based libraries](https://onlinelibrary.wiley.com/doi/abs/10.1002/qsar.200420016), Bork, J. T.; Lee, J. W.; Chang, Y. T.* QSAR Comb. Sci. 2004, 23, 245-260.

1. [Strategies for facilitated forward chemical genetics](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.200400047), Khersonsky, S. M.; Chang, Y. T.* ChemBioChem 2004, 5, 903-908.

1. [Forward chemical genetics: library scaffold design](https://www.eurekaselect.com/article/7255), Khersonsky, S. M.; Chang, Y. T.* Comb. Chem. High Throughput Screening 2004, 7, 645-652.

1. [Dedifferentiation? What’s next?](https://chooser.crossref.org/?doi=10.1124%252Fmi.4.2.5), Kim, S.; Rosania, G. R.; Chang, Y. T.* Mol. Interv. 2004, 4, 83-85.

1. [Tools for target identification and validation](https://www.sciencedirect.com/science/article/pii/S1367593104000778), Wang, S.; Sim, T.; Kim, Y. S.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2004, 8, 371-377.

1. [Safety-Catch Approach to Orthogonal Synthesis of Triazine Library](https://pubs.acs.org/doi/full/10.1021/cc049965v), Khersonsky, S. M.; Chang, Y. T.* J. Comb. Chem. 2004, 6, 474-477.

1. [Molecular evolution using intramolecular acyl migration on myo-Inositol benzoates with thermodynamic and kinetic selectors](https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.200400234), Ahn, Y. H.; Chang, Y. T.* Chem. Eur. J., 2004, 10, 3543-3547.

1. [Molecular evolution on chiro-Inositol dibenzoate using intramolecular acyl migration and selection by phenyl boronic acid](https://pubs.acs.org/doi/10.1021/cc030046z), Ahn, Y. H.; Chang, Y. T.* J. Comb. Chem. 2004, 6, 293-296.

1. [Distinctive expression of Myf5 in relation to differentiation and plasticity of newt muscle cells](http://www.ijdb.ehu.es/web/paper/031787yi/distinctive-expression-of-myf5-in-relation-to-differentiation-and-plasticity-of-newt-muscle-cells), Imokawa, Y.; Gates, P. B. Chang, Y. T.; Simon, H. G., Brockes, J. P. Int. J. Dev. Biol. 2004, 48, 285-291.

1. [Identification of a novel protein regulating microtubule stability through a chemical approach](https://www.sciencedirect.com/science/article/pii/S1074552103002989), Wignall, S. M.; Gray, N. S.; Chang, Y. T. Juarez, L.; Jacob, R. Burlingame, A.; Schultz, P. G.; Heald, R. Chem. Biol. 2004, 11, 135-246.

1. [Tagged library approach to chemical genomics and proteomics](https://www.sciencedirect.com/science/article/pii/S1367593103001650?via%253Dihub), Mitsopoulos, G.; Walsh, D. P.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2004, 8, 26-32.

1. [Chemoinformatic Analysis of a Supertargeted Combinatorial Library of Styryl Molecules](https://pubs.acs.org/doi/10.1021/ci0341215), Shedden, K.; Brumer, J.; Chang, Y. T.; Rosania, G. R. J. Chem. Inf. Comput. Sci. 2003, 43, 2068-2080.

1. [Facilitated forward chemical genetics using tagged triazine library and zebrafish embryo screening](https://pubs.acs.org/doi/full/10.1021/ja035334d), Khersonsky, S. M.; Jung, D. W.; Kang, T. W.; Walsh, D. P.; Moon, H. S.; Jo, H.; Jacobson, E. M.; Shetty, V.; Neubert, T. A.; Chang, Y. T.* J. Am. Chem. Soc. 2003, 125, 11804-11805.

1. [Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment](https://www.sciencedirect.com/science/article/pii/S0006291X03012920?via%253Dihub), Lee-Huang, S.; Zhang, L.; Huang, P. L.; Chang, Y. T.; Huang, P. L. Biochem. Biophys. Res. Commun. 2003, 307, 1029-1037.

1. [Effects of Tubulyzines, Novel Microtubule-Binding Triazine Molecules, on Endothelial Progenitor Cell Differentiation](https://www.semanticscholar.org/paper/Effects-of-Tubulyzines%252C-Novel-Microtubule-Binding-Park-Lee/f1aa094fadd86bb99d4825f10222d9307247fe24), Park, H. E.; Lee, S. Y.; Ahn, H. Y.; Shin, J. C.; Chang, Y. T.; Joe, Y. A. J. Appl. Pharmacol. 2003, 11, 85-90.

1. [Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles](https://aacrjournals.org/cgi/pmidlookup), Shedden, K.; Xie, X. T.; Chandaroy, P.; Chang, Y. T.; Rosania, G. R. Cancer Res. 2003, 63, 4331-4337.

1. [Development of novel cell-permeable DNA sensitive dyes using combinatorial synthesis and cell based screening](https://pubs.rsc.org/en/content/articlelanding/2003/CC/b303960a#!divAbstract), Lee, J. W.; Jung, M.; Rosania, G. R.; Chang, Y. T.* ChemComm 2003, 1852-1853.

1. [Palladium-catalyzed cross-coupling reaction of resin-bound chlorotriazines](https://www.sciencedirect.com/science/article/pii/S0040403903014515), Bork, J. T.; Lee, J. W.; Chang, Y. T.* Tetrahedron Lett. 2003, 44, 6141-6144.

1. [Tubulyzine a novel trisubstituted triazine prevents the early cell death of transplanted myoblasts and improves myoblast transplantation success](https://cdnsciencepub.com/doi/10.1139/o03-054#.XZrvBEYzaUk), El Fahime, E.; Bouchentouf, M.; Benabdallah, B. F.; Skuk, D.; Chang, Y. T.; Tremblay, J. P. Biochem. Cell Biol. 2003, 81, 81-90.

1. [Understanding the effects of the polymer support on reaction rates and kinetics: knowledge toward efficient synthetic design](https://www.sciencedirect.com/science/article/pii/S1367593103000541?via%253Dihub), Walsh, D. P; Wu, D.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2003, 7, 353-361.

1. [Nitrophenol resins for facile amide and sulfonamide library synthesis](https://pubs.acs.org/doi/10.1021/cc0200890), Lee, J. W.; Louie, Y. Q.; Walsh, D. P.; Chang, Y. T.* J. Comb. Chem. 2003, 5, 330-335.

58. [Recent advances in glycomics and glycogenetics](https://www.eurekaselect.com/article/25913), Khersonsky, S. M.; Ho, C. M.; Garcia, M. F.; Chang, Y. T.* Curr. Top. Med. Chem. 2003, 3, 617-643 (with Preface: Chemical Biology and Chemical Genetics, Rosania, G. R. & Chang, Y. T. as Guest Editors).

1. [Novel Orthogonal Strategy toward Solid Phase Synthesis of 1,3,5-Substituted Triazines](https://pubs.acs.org/doi/10.1021/ol027195v), Bork, J.; Lee, J. W.; Khersonsky, S. M.; Moon, H. S.; Chang, Y. T. * Org. Lett. 2003, 5, 117-120.

1. [Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold](https://pubs.acs.org/doi/10.1021/ja027587x), Rosania, G. R.; Lee, J. W.; Ding, L.; Yoon, H. S.; Chang, Y. T.* J. Am. Chem. Soc. 2003, 125, 1130-1131.

1. [Single Resin Bead Kinetics Using Real Time Fluorescence Measurements](https://koreascience.or.kr/article/JAKO200202727364603.page), Parikh, P. B.; Kim, Y. S.; Chang, Y. T.* Bull. Korean Chem. Soc. 2002, 23, 1509-1510.

1. [A Novel Microtubule destabilizing Entity from Orthogonal Synthesis of Triazine Library and Zebrafish Embryo Screening](https://pubs.acs.org/doi/full/10.1021/ja026720i), Moon, H. S.; Jacobson, E. M.; Khersonsky, S. M.; Luzung, M. R.; Walsh, D. P.; Xiong, W.; Lee, J. W.; Parikh, P. B.; Lam, J. C.; Kang, T. W.; Rosania, G. R.; Schier, A. F.; Chang, Y. T.* J. Am. Chem. Soc. 2002, 124, 11608-11609. Highlighted at “Chemical Biology (Paper alert), Hall, D. G. Curr. Opin. Chem. Biol. 2002, 6, 719.”

1. [Purine based inhibitors of Inositol-1,4,5-trisphosphate-3-kinase](https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/1439-7633%252820020902%25293%253A9%253C897%253A%253AAID-CBIC897%253E3.0.CO%253B2-B), Chang, Y. T.*; Choi, G.; Bae, Y. S.; Burdett, M.; Moon, H. S.; Lee, J. W.; Gray, N. S.; Schultz, P. G.; Meijer, L.; Chung, S. K.; Choi, K. Y.; Suh, P. G.; Ryu, S. H. ChemBioChem 2002, 3, 897-901.

1. [Divergent synthesis of all possible optically active regioisomers of myo-inositol tris- and tetrakisphosphates](https://pubs.acs.org/doi/full/10.1021/jo0257694?src=recsys), Chung, S. K.; Kwon, Y. U.; Shin, J. H.; Chang, Y. T.; Lee, C. G.; Shin, B. G.; Kim, K. C.; Kim, M. J. J. Org. Chem. 2002, 67, 5626-2637.

1. [Combinatorial Discovery of Novel Fluorescent Dyes Based on DapoxylTM](https://www.sciencedirect.com/science/article/pii/S0040403902009991), Zhu, Q.; Yoon, H. S.; Parikh, P. B.; Chang, Y. T.; Yao, S. Q. Tetrahedron Lett. 2002, 43, 5083-5086.

1. [Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors](https://www.sciencedirect.com/science/article/pii/S107455210200131X?via%253Dihub), Perez, O. D.; Chang, Y. T.; Rosania, G.; Sutherlin, D.; Schultz, P. G. Chem. Biol. 2002, 9, 475-483 (with cover picture).

1. [The synthesis and biological characterization of a ceramide library](https://pubs.acs.org/doi/full/10.1021/ja017576o), Chang, Y. T.*; Choi, J.; Ding, S.; Prieschl, E. E.; Baumruker, T.; Lee, J. M.; Chung, S. K.; Schultz, P. G. J. Am. Chem. Soc. 2002, 124, 1856-1857.

1. [Comparative resin kinetics using in situ fluorescence measurements](https://pubs.acs.org/doi/10.1021/cc010063t), Walsh, D. P.; Pang, C.; Parikh, P. B.; Kim, Y. S.; Chang, Y. T.* J. Comb. Chem. 2002, 4, 204-208.

1. [The identification and quantification of para-phenylenediamine in a temporary black henna tattoo](https://oce.ovid.com/article/01634989-200203000-00004/HTML), Brancaccio, R. R.; Brown, L. H.; Chang, Y. T.; Fogelman, J. P.; Mafong, E. A.; Cohen, D. E. Am. J. Contact Dermatitis 2002, 13, 15-18.

1. [(±)-1,2;5,6-Di-O-isopropylidene-myo-inositol and (±)-1,2;4,5-di-O-isopropylidene-6-O-benzoyl-myo-inositol: a practical preparation of key intermediates for myo-inositol phosphates](https://www.sciencedirect.com/science/article/pii/S0008621501002865), Khersonsky, S. M.; Chang, Y. T.* Carbohydr. Res. 2002, 337, 75-78.

1. [Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors](https://pubs.acs.org/doi/10.1021/jm010451%252B), Chang, Y. T.*; Wignall, S. M.; Rosania, G. R.; Gray, N. S.; Hanson, S. R.; Su, A. I.; Merlie, Jr., J.; Moon, H. S.; Sangankar, S. B.; Perez, O.; Heald, R.; Schultz, P. G. J. Med. Chem. 2001, 44, 4497-4500.

1. [Discovery of estrogen sulfotransferase inhibitors from a purine library screen](https://pubs.acs.org/doi/10.1021/jm010171u), Verdugo, D. E.; Cancilla, M. T.; Ge, X.; Gray, N. S.; Chang, Y. T.; Schultz, P. G.; Negishi, M.; Leary, J. A.; Bertozzi, C. R. J. Med. Chem. 2001, 44, 2683-2686.

1. [Inositol phospholipid pathway inhibitors and regulators](https://www.tandfonline.com/doi/abs/10.1517/13543776.11.1.45), Chang, Y. T.*; Rosania, G. R.; Chung, S. K. Expert Opin. Ther. Pat. 2001, 11, 45-59.

1. [Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilized inhibitors](https://www.sciencedirect.com/science/article/pii/S1074552100001241), Knockaert, M.; Gray, N.; Damiens, E.; Chang, Y. T.; Grellier, P.; Grant, K.; Fergusson, D.; Mottram, J.; Soete, M.; Dubremetz, J. F., Le Roch K.; Doerig, C.; Schultz, P. G.; Meijer, L. Chem. Biol. 2000, 7, 411-422.

1. [Discovery of carbohydrate sulfotransferase inhibitors from a kinase-directed library](https://onlinelibrary.wiley.com/doi/abs/10.1002/%2528SICI%25291521-3773%252820000403%252939%253A7%253C1303%253A%253AAID-ANIE1303%253E3.0.CO%253B2-0?sid=nlm%253Apubmed), Armstrong, J. I.; Portley, A. R.; Chang, Y. T.; Nierengarten, D. M.; Cook, B. N.; Bowman, K. G.; Bishop, A.; Gray, N. S.; Shokat, K. M.; Schultz, P. G.; Bertozzi, C. R. Angew. Chem., Int. Ed. Engl., 2000, 39, 1303-1306.

1. [A Novel DAST-induced Debenzylative Cycloetherization in D-1,2-O-Isopropylidene-3,4,5-tri-O-benzyl-myo-inositol](https://onlinelibrary.wiley.com/doi/full/10.1002/chin.200029175), Chung, S. K.; Kwon, Y. U.; Ahn, Y. H.; Jeong, T. H.; Chang, Y. T. Bull. Korean Chem. Soc. 2000, 21, 274-276.

1. [Myoseverin: a microtubule binding molecule with novel cellular effects, Rosania](https://www.nature.com/articles/nbt0300_304), G. R.; Chang, Y. T.; Perez, O.; Sutherlin, D.; Dong, H.; Lockhart, D. J.; Schultz, P. G. Nat. Biotechnol. 2000, 18, 304-308 (with cover picture): Highlighted at “Combinatorial chemistry gives cell biology some muscle, Hall, D. G. Nat. Biotechnol. 2000, 18, 261-262”.

1. [Targeting hyperproliferative disorders with cyclin dependent kinase inhibitors](https://www.tandfonline.com/doi/abs/10.1517/13543776.10.2.215?journalCode=ietp20), Rosania, G. R.; Chang, Y. T. Expert Opin. Ther. Pat. 2000, 10, 215-230.

1. [Versatile fluorescence labeling method using activated esters on solid support](https://www.sciencedirect.com/science/article/pii/S0960894X99004229?via%253Dihub), Chang, Y. T.; Schultz, P. G. Bioorg. Med. Chem. Lett. 1999, 9, 2479-2482.

1. [Synthesis of All Possible Regioisomers of scyllo-Inositol Phosphate](https://www.sciencedirect.com/science/article/pii/S0968089699001832?via%253Dihub), Chung, S. K.; Kwon, Y. U.; Chang, Y. T.; Sohn, K. H.; Shin, J. H.; Park, K. H.; Hong, B. J.; Chung, I. H. Bioorg. Med. Chem. 1999, 7, 2577-2589.

1. [Recombinant p42IP4, a brain-specific 42-kDa high-affinity Ins(1,3,4,5)P4 receptor protein, specifically interacts with lipid membranes containing Ptd-I(3,4,5)P3](https://febs.onlinelibrary.wiley.com/doi/full/10.1046/j.1432-1327.1999.00326.x?sid=nlm%253Apubmed), Hanck, T.; Stricker, R.; Krishna, U. M.; Falck, J. R.; Chang, Y. T.; Chung, S. K.; Reiser, G. Eur. J. Biochem. 1999, 261, 577-584.

1. [Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors](https://www.sciencedirect.com/science/article/pii/S1074552199800489?via%253Dihub), Chang, Y. T.; Gray, N.; Rosania, G. R.; Sutherlin, D. P.; Kwon, S.; Norman, T.; Sarohia, R.; Leost, M.; Meijer, L.; Schultz, P. G. Chem. Biol. 1999, 6, 361-375 (with cover picture).

1. [A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts](https://www.pnas.org/doi/full/10.1073/pnas.96.9.4797), Rosania, G. R.; Merlie, Jr., J.; Gray, N.; Chang, Y. T.; Schultz, P. G.; Heald, R. Proc. Natl. Acad. Sci. USA 1999, 96, 4797-4802.

1. [An Efficient Synthesis of D-myo-Inositol 1,3,4,5-tetrakisphosphate](https://www.semanticscholar.org/paper/An-Efficient-Synthesis-of-D-myo-Inositol-Chung-Chang/08d2f412bf6bfdfcede86ce9c828ded2c0d111fd), Chung, S. K.; Chang, Y. T.; Lee, E. J.; Kwon, Y. U. Kor. J. Med. Chem. 1998, 8, 18-21.

1. [Syntheses of Two Enantiomeric Pairs of myo-Inositol-(1,2,4,5,6) and -(1,2,3,4,5)pentakisphosphate](https://www.sciencedirect.com/science/article/pii/S0960894X98002455?via%253Dihub), Chung, S. K.; Chang, Y. T.; Lee, E. J.; Shin, B. G.; Kwon, Y. U.; Kim, K. C.; Lee, D. H.; Kim, M. J. Bioorg. Med. Chem. Lett. 1998, 8, 1503-1506.

1. [Syntheses of D- and L-myo-Inositol-1,2,4,5-tetrakisphosphate, the Stereoselectivity of I(1,4,5)P3 Receptor Recognition](https://www.sciencedirect.com/science/article/pii/S0960894X9800081X?via%253Dihub), Chung, S. K.; Shin, B. G.; Chang, Y. T.; Suh, B. C.; Kim, K. T. Bioorg. Med. Chem. Lett. 1998, 8, 659-662.

29. [Syntheses of D-myo-Inositol-1,2,6-trisphosphate and -2,6-bisphosphate](https://www.tandfonline.com/doi/abs/10.1080/07328309808002899), Chung, S. K.; Yu, S. H.; Chang, Y. T. J. Carbohydr. Chem. 1998, 17, 385-390.

1. [Synthesis of All Regioisomers of myo-Inositol Bisphosphates](https://www.tandfonline.com/doi/abs/10.1080/07328309808002898), Chung, S. K.; Chang, Y. T.; Kwon, Y. U. J. Carbohydr. Chem. 1998, 17, 369-384.

1. [Molecular Probes for the Binding Site of Inositol 1,4,5-trisphosphate (IP3) 3-Kinase and Comparison with IP3 Receptor](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M970205&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Choi, G.; Chang, Y. T.; Chung, S. K.; Choi, K. Y. Kor. J. Med. Chem. 1997, 7, 106-114.

1. [Selective Benzoylations of myo-Inositol Orthoformate and a Practical Synthesis of myo-Inositol-1,3,4,5-tetrakisphosphate](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M970201&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Chung, S. K.; Chang, Y. T.; Lee, J. W.; Ji, Y. K. Kor. J. Med. Chem. 1997, 7, 82-85.

1. [Syntheses of myo-Inositol-1,2,3,5- and -2,4,5,6-tetrakisphosphates, Unusual Inhibitors of myo-Inositol-1,4,5-trisphosphate 3-Kinase](https://www.sciencedirect.com/science/article/pii/S0960894X97100610), Chung, S. K.; Chang, Y. T. Bioorg. Med. Chem. Lett. 1997, 7, 2715-2718.

1. [Molecular Interactions of All Possible Regioisomers of Synthetic myo-Inositol Phosphates with myo-Inositol-1,4,5-trisphosphate 3-Kinase](https://www.sciencedirect.com/science/article/pii/S0960894X97100609), Choi, G.; Chang, Y. T.; Chung, S. K.; Choi, K. Y. Bioorg. Med. Chem. Lett. 1997, 7, 2709-2714.

1. [Microwave Enhanced Knoevenagel Condensation of Malonic Acid on Basic Alumina](https://www.tandfonline.com/doi/abs/10.1080/00397919708005456), Kwon, P. S.; Kim, Y. M.; Kang, C. J.; Kwon, T. W.; Chung, S. K.; Chang, Y. T. Syn. Commun. 1997, 27, 4091-4100.

1. [Synthesis of D-Galactopyranosyl-1,2,6-trisphosphate as a Geometric Analogue of D-myo-Inositol 1,4,5-trisphosphate](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M970111&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Chung, S. K.; Kwon, Y. U.; Chang, Y. T. Kor. J. Med. Chem. 1997, 7, 63-68.

1. [Solution Conformation and Kinetic Acidity of 1,2;4,5-Di-O-isopropylidene-myo-inositol](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M970104&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Chung, S. K.; Chang, Y. T. Kor. J. Med. Chem. 1997, 7, 15-18.

1. [Microwave Enhanced Knoevenagel Condensation of Ethyl Cyanoacetate with Aldehydes](https://www.tandfonline.com/doi/abs/10.1080/00397919708003323), Kim, S. Y.; Kwon, P. S.; Kwon, T. W.; Chung, S. K.; Chang, Y. T. Syn. Commun. 1997, 27, 533-541.

1. [Theoretical Studies of Regioselectivity of myo-Inositol Derivatives: Importance of Solvent Dielectric Constants](https://pubs.acs.org/doi/10.1021/jp9633097), Kim, K. S.; Cho, S. J.; Oh, K. S.; Son, J. S.; Kim, J.; Lee, J. Y.; Lee, S. J.; Lee, S.; Chang, Y. T.; Chung, S. K.; Ha, T. K.; Lee, B. S.; Lee, I. J. Phys. Chem. 1997, 101, 3776-3783.

18. Binding and Activity of the Nine Possible Regioisomers of myo-Inositol Tetrakisphosphate at the Inositol 1,4,5-Trisphosphate Receptor, Burford, N. T.; Nahorski, S. R.; Chung, S. K.; Chang, Y. T.; Wilcox, R. A. Cell Calcium 1997, 21, 301-310.

1. Rapid Kinetic Measurements of 45Ca2+ Mobilization Reveal that Inositol 2,4,5-Trisphosphate is a Partial Agonist at Hepatic Inositol Trisphosphate Receptor, Marchant, J. S.; Chang, Y. T.; Chung, S. K.; Irvine, R. F.; Taylor, C. W. Biochem. J. 1997, 321, 573-576.

1. Determination of Specificity of a High Affinity Inositol-1,3,4,5-tetrakisphosphate Binding Site at a 42 kD Receptor Protein: Comparison of Affinities of All Regioisomers of Inositol Tris-, Tetrakis-, and Pentakisphosphate, Stricker, R.; Chang, Y. T.; Chung, S. K.; Reiser, G. Biochem. Biophys. Res. Commun. 1996, 228, 596-604.

1. [Synthesis of myo-Inositol-1,2,3-trisphosphate by Selective Benzylation: the Iron Binding Motif of Phytic acid (IP6)](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M960210&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Chung, S. K.; Chang, Y. T. Kor. J. Med. Chem. 1996, 6, 253-258.

1. [Synthesis of All Possible Regioisomers of myo-Inositol Monophosphate](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M960202&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Chung, S. K.; Chang, Y. T. Kor. J. Med. Chem. 1996, 6, 162-165.

1. Crystal Structures of DL-1,4-Di-O-benzoyl-2,3-O-isopropylidene-myo-inositol and DL-1,4-Di-O-benzoyl-5,6-O-isopropylidene-myo-inositol: a Conformational Analysis, Chung, S. K.; Chang, Y. T.; Whang, D.; Kim, K. Carbohydr. Res. 1996, 295, 1-6.

1. Synthesis of All Possible Regioisomers of myo-Inositol Pentakisphosphate, Chung, S. K.; Chang, Y. T. Bioorg. Med. Chem. Lett. 1996, 6, 2039-2042.

1. [Ab initio Conformational Study of 1,2,;4,5-Di-O-isopropylidene-myo-inositol](https://pubs.acs.org/doi/10.1021/jp9603795), Lee, S. J.; Cho, S. J.; Oh, K. S.; Cui, C.; Ryu, Y.; Chang, Y. T.; Kim, K. S.; Chung, S. K. J. Phys. Chem. 1996, 100, 10111-10115.

1. [Synthesis and Iron Binding Studies of myo-Inositol-1,2,3-trisphosphate and DL-myo-Inositol-1,2-bisphosphate, and Iron Binding Studies of All myo-Inositol-tetrakisphosphates](https://linkinghub.elsevier.com/retrieve/pii/0008621595003614), Spiers, I. D.; Barker, C. J.; Chung, S. K.; Chang, Y. T.; Freeman, S.; Gardiner, J. M.; Hirst, P. H.; Lambert, P. A.; Michell, R. H.; Poyner, D. R.; Schwalbe, C. H.; Smith, A. W.; Solomons, K. R. H. Carbohydr. Res. 1996, 282, 81-99.

1. [New Approach to the Synthetic Problems of myo-Inositol Phosphates and Their Biological Utilities](https://onlinelibrary.wiley.com/doi/10.1002/chin.199822230), Chung, S. K.; Chang, Y. T.; Sohn, K. H. in “Medicinal Chemistry: Today and Tomorrow”, pp 63-68, Ed. M. Yamazaki, Blackwell Science, 1996.

1. [A Divergent Approach toward Synthesis of myo-Inositol Phosphates: Acyl Migration and Regioselectivity](https://www.semanticscholar.org/paper/A-divergent-approach-toward-synthesis-of-Acyl-and-Chung-Chang/0ac9a42f97a363cfbf6aceec6c6b17ce34c1dd31), Chung, S. K.; Chang, Y. T.; Ryu, Y. Pure Appl. Chem. 1996, 68, 931-935.

1. [Practical Divergent Synthesis of All Possible Regioisomers of myo-Inositol Trisphosphates](https://pubs.rsc.org/en/content/articlehtml/1996/cc/cc9960000163), Chung, S. K.; Chang, Y. T.; Sohn, K. H. J. Chem. Soc., Chem. Commun. 1996, 163-164.

1. [Specificity of the Purified Inositol-1,3,4,5-tetrakisphosphate-binding Protein from Porcine Platelets](https://febs.onlinelibrary.wiley.com/doi/abs/10.1016/0014-5793%252894%252901435-4?sid=nlm%253Apubmed), Cullen, P. J.; Chung, S. K.; Chang, Y. T.; Dawson, A. P.; Irvine, R. F. FEBS Lett. 1995, 358, 240-242.

1. [Base-catalyzed Acyl Migration in myo-Inositol Dibenzoates](https://pubs.rsc.org/en/content/articlelanding/1995/c3/c39950000013#!divAbstract), Chung, S. K.; Chang, Y. T. J. Chem. Soc., Chem. Commun. 1995, 13-14.

1. [Synthesis of All Possible Regioisomers of myo-Inositol Tetrakisphosphates](https://pubs.rsc.org/en/content/articlelanding/1995/C3/C39950000011#!divAbstract), Chung, S. K.; Chang, Y. T. J. Chem. Soc., Chem. Commun. 1995, 11-12.

1. [Synthesis of myo-Inositol-1,4,5-, 2,4,6-, and 1,3,5-trisphosphate](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M940110&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=4&no=&page=57&year1=1993&year2=1995&view=10&qpage=j_search&abstract=), Chung, S. K.; Chang, Y. T.; Sohn, K. H. Kor. J. Med. Chem. 1994, 4, 57-65.

1. [Crystal Structure of 1,2;4,5-Di-O-isopropylidene myo-Inositol and 1,2;5,6-Di-O-isopropylidene myo-Inositol: a Conformational Analysis](https://www.sciencedirect.com/science/article/pii/0008621594800510https://www.sciencedirect.com/science/article/pii/0008621594800510), Chung, S. K.; Ryu, Y.; Chang, Y. T.; Whang, D.; Kim, K. Carbohydr. Res. 1994, 253, 13-18.

1. [Synthesis of myo-Inositol-1,4,5-trisphosphate and myo-Inositol-1,4-bisphosphate](https://journal.kcsnet.or.kr/main/j_search/j_abstract_view.htm?code=M920105&cpage=1&qpage=j_search&spage=j_search&journal=A&vol=&no=&page=&year1=0&year2=0&view=10&qpage=j_search&abstract=), Chung, S. K.; Ryu, Y.; Chang, Y. T.; Moon, S. H. Kor. J. Med. Chem. 1992, 2, 33-44.

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