Publications

 

315. Gold nanoshell-mediated remote myotube activation, Marino, A.; Arai, S.; Hou, Y.; Degl’Innocenti, A.; Cappello, V.; Mazzolai, B.; Chang, Y. T.; Mattoli, V.; Suzuki, M.; Ciofani, G. ACS Nano 2017, 11, 2494-2508.

314. Real-time in vivo hepatotoxicity monitoring through chromophore-conjugated upconversion nanoprobes, Peng, J.*; Samanta, A.; Zeng, X.; Han, S.; Wang, L.; Su, D.; Loong, D. T. B.; Kang, N. Y.; Park, S. J.; All, A. H.; Jiang, W.; Yuan, L.*; Liu, X.*; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2017, 56, 4165-4169.

313. Two-photon dye cocktail for dual-color 3D imaging of pancreatic beta and alpha cells in live islets, Agrawalla, B. K.; Lee, H. W.; Phue, W. H.; Raju, A.; Kim, J. J.; Kim, H. M.; Kang, N. Y.*; Chang, Y. T.* J. Am. Chem. Soc. 2017, 139, 3480-3487.

312. The vital dye CDr10b labels the Zebrafish mid-intestine and lumen, Sander, V.; Patke, S.; Lee, J. Y.; Chang, Y. T.; Davidson, A. J. Molecules 2017, 22, 454.

311. Development of a BODIPY-based fluorescent probe for imaging pathological tau aggregates in live cells, Lim, S.; Haque, M. M.; Su, D.; Kim, D.; Lee, J. S.; Chang, Y. T.; Kim, Y. K. Chem. Commun. 2017, 53, 1607-1610.

310. Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe, Cheng, D.; Pan, Y.; Wang, L.; Zeng, Z.; Yuan, L.; Zhang, X.; Chang, Y. T. J. Am. Chem. Soc. 2017, 139, 285-292.309. 

309. Development of pH-responsive BODIPY probes for staining late endosome in live cells, Miao, F.; Uchinomiya, S.; Ni, Y.; Chang, Y. T.*; Wu, J.* ChemPlusChem 2016, 81, 1209-1215.

308. A Fluorescent Probe for Neural Stem/Progenitor Cells with High Differentiation Capability into Neurons, Kim, B.; Feng, S.; Yun, S. W.; Leong, C.; Satapathy, R.; Wan, S. Y.; Chang, Y. T.* ChemBioChem 2016, 17, 2118-2122.

307. Photodynamic approach for teratoma-free pluripotent stem cell therapy using CDy1 and visible light, Cho, S.; Kim, S. Y.; Park, S. J.; Song, N.; Kwon, H. Y.; Kang, N. Y.; Moon, S. H.; Chang, Y. T.*; Cha, H. J.* ACS Cent. Sci. 2016, 2, 604-607.

306. Specific Triazine Herbicides Induce Amyloid-b42 Production, Portelius, E.; Durieu, E.; Bodinb, M.; Cam, M.; Pannee, J.; Charlotte Leuxe, Mabondzo, A.; Oumata, N.; Galons, H.; Lee, J. Y.; Chang, Y. T.; Stueber, K.; Koch, P.; Fontaine, G.; Potier, M.; Manousopoulou, A.; Garbis, S.; Covaci, A.; Van Dam, D.; De Deyn, P.; Karg, F.; Flajolet, M.; Omori, C.; Hata, S.; Suzuki, T.; Blennow, K.; Zetterberg, H.; Meijer, L. J. Alzheimer’s Dis. 2016, 54, 1593-1605.

305. Naphthalene-fused BODIPY near-infrared dye as a stable contrast agent for in vivo photoacoustic imaging, Ni, Y.; Kannadorai, R. K.; Peng, J.; Yu, S. W. K.; Chang, Y. T.*; Wu, J.* Chem. Commun. 2016, 52, 11504-11507.

304. A Simple BODIPY-based viscosity probe for imaging of cellular viscosity in live cells, Su, D.; Teoh, C. L.; Gao, N.; Xu, Q. H.; Chang, Y. T.* Sensors 2016, 16, 1397.

303. Discerning the chemistry in individual organelles with small molecule fluorescent probes, Xu, W.; Zeng, Z.; Jiang, J. H.*; Chang, Y. T.*; Yuan, L.* Angew. Chem., Int. Ed. Engl. 2016, 55, 13658-13699.

302. CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer, Roy, R.; Hoppe, M.; Sharma, N.; Srivastava, S.; Tan, K. T.; Yang, H.; Voon, D.; Pang, B.; Teh, M.; Murata-Kamiya, N.; Hatakeyama, M.; Samanta, A.; Chang, Y. T.; Ho, K. Y.; Ito, Y.; Tan, P.; Soong, R.; Koeffler, H.; Yeoh, K.; Jeyasekharan, A. Oncotarget 2016, 7, 55290-55301.

301. Boronic acid: a bio-inspired strategy to increase the sensitivity and selectivity of fluorescent NADH probe, Wang, L; Zhang, J.; Kim, B.; Peng, J.; Berry, S. N.; Ni, Y.; Su, D.; Lee, J.; Yuan, L.; Chang, Y. T.* J. Am. Chem. Soc. 2016, 138, 10394-10397.

300. Development of background-free tame fluorescent probes for intracellular live cell imaging, Alamudi, S. H.; Satapathy, R.; Kim, J.; Su, D.; Ren, H.; Das, R.; Hu, L.; Alvarado-Martínez, E.; Lee, J. Y.; Hoppmann, C.; Peña-Cabrera, E.; Ha, H. H.; Park, H. S.*; Wang, L.*; Chang, Y. T.* Nat. Commun. 2016, 7, 11964.

299. Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells, Berry, S. N.; Soto-Cerrato, V.; Howe, E. N. W.; Clarke, H. J.; Mistry, I.; Tavassoli, A.; Chang, Y. T.; Pérez-Tomás, R.; Gale, P. A. Chem. Sci. 2016, 7, 5069-5077.

298. Prediction of intracellular localization of fluorescent dyes using QSAR models, Uchinomiya, S.; Horobin, R. W.; Alvarado-Martínez, E.; Peña-Cabrera, E.*; Chang, Y. T.* Comb. Chem. High Throughput Screening 2016, 19, 378-383.

297. Quantitative Measurement of Caffeine by Optical Methods, Xu, W.; Chang, Y. T.* in volume 3 of Neuropathology of Drug Addictions and Substance Misuse. pp 815-826, 2016.

296. Detection of GHB by optical methods, Xu, W.; Zhai, D.; Chang, Y. T.* in volume 2 of Neuropathology of Drug Addictions and Substance Misuse. pp 529-535, 2016.

295. RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming, Toh, C. X.; Chan, J. W.; Chong, Z. S.; Wang, H. F.; Guo, H. C.; Satapathy, S.; Ma, D.; Goh, G. Y.; Khattar, E.; Yang, L.; Tergaonkar, V.; Chang, Y. T.; Collins, J. J.; Daley, G. Q.; Wee, K. B.; Farran, C. A.; Li, H.; Lim, Y. P.; Bard, F. A.; Loh, Y. H. Cell Rep. 2016, 15, 2597-2607.

294. A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase, Zhang, L.; Er, J. C.; Jiang, H.; Li, X.; Luo, Z.; Ramezani, T.; Feng, Y.; Tang, M. K.; Chang, Y. T.; Vendrell, M. Chem. Commun. 2016, 52, 9093-9098.

293. Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis, Li, X.; Jiang, H.; Luo, Z.; Chang, Y. T.; Zhang, L. Chem. Commun. 2016, 52, 9086-9088.

292. Direct organelle thermometry with fluorescence lifetime imaging microscopy in single myotubes, Itoh, H.; Arai, S.; Sudhaharan, T.; Lee, S. C.; Chang, Y. T.; Ishiwata, S.; Suzuki, M.; Lane, E. B. Chem. Commun. 2016, 52, 4458-4461.

291. Diradical Approach towards BODIPY Based Near-infrared Dyes with Intense Absorption around 1100 nm, Ni, Y.; Lee, S.; Son, M.; Aratani, N.; Ishida, M.; Samanta, A.; Yamada, H.; Chang, Y. T.; Furuta, H.; Kim, D.; Wu, J. Angew. Chem., Int. Ed. Engl. 2016, 55, 2815-2819.

290. Multisite-binding switchable fluorescent probe for monitoring mitochondrial ATP level fluctuation in live cells, Wang, L.; Yuan, L.; Zeng, X.; Peng, J.; Ni, Y.; Er, J. C.; Xu, W. Agrawalla, B. K.; Su, D.; Kim, B.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2016, 55, 1773-1776.

289. Detection of pathogenic biofilms with bacterial amyloid targeting fluorescent probe, CDy11, Kim, J. Y.; Sahu, S.; Yau, Y. H.; Wang, X.; Shochat, S. G.; Nielsen, P. H.; Dueholm, M. S.; Otzen, D. E.; Lee, J.; Delos Santos, M. M.; Yam, J. K.; Kang, N. Y.; Park, S. J.; Kwon, H.; Seviour, T. W.; Yang, L.; Givskov, M.; Chang, Y. T.* J. Am. Chem. Soc. 2016, 138, 402-407.

288. Development of a highly selective, sensitive and fast response upconversion luminescent platform for hydrogen sulfide detection, Peng, J.; Teoh, C. L.; Zeng, X.; Samanta, A.; Wang, L.; Xu, W.;  Su, D.; Yuan, L.*, Liu, X.; Chang, Y. T.* Adv. Funct. Mat. 2016, 26, 191-199.

287. Axon-First Neuritogenesis on Vertical Nanowires, Kang, K.; Park, Y. S.; Park, M.; Jang, M. J.; Kim, S. M.; Lee, J.; Choi, J. Y.; Jung, D. H.; Chang, Y. T.; Yoon, M. H.; Lee, J. S.; Nam, Y.; Choi, I. S. Nano Lett. 2016, 16, 675-680.

286. Thermosensitive nanoplatforms for photothermal release of cargo from liposomes under intracellular temperature monitoring, Arai, S.; Lee, C. L. K. ; Chang, Y. T.; Satoe, H.; Sou, K. RSC Adv. 2015, 5, 93530-93538.

285. Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cells, Kim, E. S; Samanta, A.; Cheng, H. S; Ding, Z.; Han, W.; Toschi, L.; Chang, Y. T.* Mol. Biosyst. 2015, 11, 3378-3386.

284. Chemical Fluorescent Probe for Detection of Aβ Oligomers, Teoh, C. L.; Su, D.; Sahu, S.; Yun, S. W.; Drummond, E.; Prelli, F.; Lim, S.; Cho, S.; Ham, S.*; Wisniewski, T.*; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 13503-13509. Spotlights on Recent JACS Publications at J. Am . Chem. Soc. 2015, 137, 10017. (http://pubs.acs.org/doi/pdf/10.1021/jacs.5b08475)

283. A highly selective fluorescent probe for direct detection and isolation of mouse embryonic stem cells, Chandran, Y.; Kang, N. Y.; Park, S. J.; Husen, A. S.; Kim, J. Y.; Sahu, S.; Su, D.; Lee, J.; Vendrell, M.*; Chang, Y. T.* Bioorg. Med. Chem. Lett. 2015, 25, 4862-4865.

282. Identification of disulfide crosslinked tau dimer responsible for tau propagation, Kim, D.; Lim, S.; Haque, M. M.; Ryoo, N.; Hong, H. S; Rhim, H.; Lee, D.E.; Chang, Y. T.; Lee, J. S.; Cheong, E.; Kim, D. J.; Kim, Y. K. Sci. Rep. 2015, 5, 15231.

281. NeuO for Neuronal Labeling in Zebrafish, Teoh, C. L.; Er, J. C.; Mukherjee, P.; Chang, Y. T.* Tomography 2015, 1, 30-36.

280. Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes, Arora, P.; Kharkwal, S. S.; Ng, T. W.; Kunnath-Velayudhan, S.; Saini, N. K.; Johndrow, C. T.; Chang, Y. T.; Besra, G. S.; Porcelli, S. A. Chem. Phys. Lipids 2015, 191, 75-83.

279. Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation, Marino, A.; Arai, S.; Hou, Y.; Sinibaldi, E.; Pellegrino, M.; Chang, Y. T.; Mazzolai, B.; Mattoli, V.; Suzuki, M.; Ciofani, G. ACS Nano 2015, 9, 7678-7689.

278. Voices of chemical biology, Bertozzi, C. R.; Stockwell, B. R.; Kubicek, S.; Dickinson, B. C.; Chang, C. J.; Schultz, C.; Silver, P. A.; Gestwicki, J. E.; Chiosis, G.; Chattopadhyay, A.; Butcher, R. A.; Park, S. B.; Shoichet, B. K.; Flitsch, S.; Zhang, J.; Liu, D. R.; Ohnishi, Y.; Weerapana, E.; Williams, A. H.; He, C.; Moroni, A.; Thiel, G.; Chang, Y. T.; Waldmann, H.; Bogyo, M.; Oddershede, L. B.; Christopoulos, A.; Imperiali, B.; Ehrlich, H.; Chen, X.; Prescher, J. A. Nat. Chem. Biol. 2015, 11, 378-379.

277. Suppression of the TRIF-dependent signaling pathway of Toll-like receptor by CDr10b in RAW264.7 macrophages, Gu, G. J.; Ahn, S. I.; Kim, J. S.; Hong, C. Y.; Lee, S. C.; Chang, Y. T.; Choi, T. H.; Kim, B. S.; Youn, H. S. Int. Immunopharmacol. 2015, 28, 29-33.

276. A Mitochondria-Targeted Ratiometric Fluorescent Probe to Monitor Endogenously Generated Sulfur Dioxide Derivatives in Living Cells, Wang, X.; Chai, L. T.; Peng, J.; Su, D.; Yuan, L.*;  Chang, Y. T.* Biomaterials 2015, 56, 1-9.

275. Development of nucleus staining fluorescent probe for dynamic mitosis imaging in live cells, Ghosh, K. K.; Jeong, Y. M.; Kang, N. Y.; Lee, J. Y.; Wan, S. Y.; Kim, J. Y.; Yoo, J.; Kim, D.; Kim, Y. K.*; Chang, Y. T.* Chem. Commun. 2015, 51, 9336-9338.

274. Development of Targetable Two-Photon Fluorescent Probes to Image Hypochlorous Acid in Mitochondria and Lysosome in Live Cell and Inflamed Mouse Model, Yuan, L.; Wang, L.; Agrawalla, B. K.; Park, S. J.; Zhu, H.; Sivaraman, B.; Peng, J.; Xu, Q. H.; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 5930-5938.

273. Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient, Arai, S.; Suzuki, M.; Park, S. J.; Yoo, J. S.; Wang, L.; Kang, N. Y.; Ha, H. H.; Chang, Y. T.* Chem. Commun. 2015, 51, 8044-8047.

272. Glucagon-secreting alpha cell selective two-photon fluorescent probe TP-α: for live pancreatic islet imaging, Agrawalla, B. K.; Chandran, Y.; Phue, W. H.; Lee, S. C.; Jeong, Y. M.; Wan, S. Y.; Kang, N. Y.*; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 5355-5362.

271. New Targets of Molecular Imaging in Atherosclerosis: Prehension of Current Status, Park, S. J.; Kim, J. Y.; Teoh, C. L.; Kang, N. Y.; Chang, Y. T.* Anal. Sci. 2015, 31, 245-255.

270. Development of fluorescent probes specific for parallel-stranded G-quadruplexes by a library approach, Zhang, L.; Er, J. C.; Li, X.; Heng, J. J.; Samanta, A.; Chang, Y. T.; Lee, C. L. Chem. Commun. 2015, 51, 7386-7389.

269. Diversity oriented approach for chemical biology, Lee, J. S.; Lee, J. W.; Kang, N.; Ha, H. H.*; Chang, Y. T.* Chem. Rec. 2015, 15, 495-510.

268. Solid-phase synthesis of combinatorial 2,4-disubstituted-1,3,5-triazine via amine nucleophilic reaction, Moon, S. W.; Ham, J.; Chang, Y. T.; Lee, J. W. Bull. Kor. Chem. Soc. 2015, 36, 435-438.

267. Cell specific imaging probe development and biomedical applications, Kang, N. Y.; Chang, Y. T.* in “5th International Conference on Biomedical Engineering in Vietnam”, pp 211-214, Eds. V. Van Toi and T. H. Lien Phung, Springer: Switzerland, 2015.

266. Rootin, a compound that inhibits root development through modulating PIN-mediated auxin distribution, Jeong, S.; Kim, J. Y.; Choi, H.; Kim, H.; Lee, I.; Soh, M. S.; Nam, H. G.; Chang, Y. T.*; Lim, P. O.*; Woo, H. R.* Plant Sci. 2015, 233, 116-126.

265. The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications, Su, D.; Teoh, C. L.; Samanta, A.; Kang, N. Y.; Park, S. J.; Chang, Y. T.* Chem. Commun. 2015, 51, 3989-3992.

264. Synthesis and systematic evaluation of dark resonance energy transfer (DRET)-based library and its application in cell imaging, Su, D.; Teoh, C. L.; Kang, N. Y.; Yu, X.; Sahu, S.; Chang, Y. T.* Chem. Asian J. 2015, 10, 581-585.

263. CDy6, a photostable probe for long-term real-time visualization of mitosis and proliferating cells, Jeong, Y. M.; Duanting, Z.; Hennig, H.; Samanta, A.; Agrawalla, B. K.; Bray, M. A.; Carpenter, A. E.; Chang, Y. T.* Chem. Biol. 2015, 22, 299-307.

262. New insight of squaraine-based biocompatible surface-enhanced Raman scattering nanotag for cancer-cell imaging, Ramya, A.; Samanta, A.; Nisha, N.; Chang, Y. T.; Maiti, K. K. Nanomedicine 2015, 10, 561-571.

261. NeuO: a fluorescent chemical probe for live neuron labeling, Er, J. C.; Leong, C.; Teoh, C. L.; Yuan, Q.; Merchant, P.; Dunn, M.; Sulzer, D.; Sames, D.; Bhinge, A.; Kim, D.; Kim, S. M.; Yoon, M. H.; Stanton, L. W.; Je, S. H.; Yun, S. W.*; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2015, 54, 2442-2446. Highlighted at “A library of bright ideas, C&En News, 2015 (March 23), 93 (12), p 39-40”

260. High-efficiency in vitro and in vivo detection of Zn2+ by dye-assembled upconversion nanoparticles, Peng, J.; Xu, W.; Teoh, C. L.; Han, S.; Kim, B.; Samanta, A.; Er. J. C.; Wang, L.; Yuan, L.; Liu, X.; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 2336-2342.

259. The small molecule probe PT-Yellow labels the renal proximal tubules in zebrafish, Sander, V.; Patke, S. V.; Sahu, S.; Teoh, C. L.; Peng, P.; Chang, Y. T.; Davidson, A. J. Chem. Commun. 2015, 51, 395-398.

258. Sensitive multiplex detection of serological liver cancer biomarkers using SERS active photonic crystal fiber probe, Dinish, U. S; Balasundaram, G.; Chang, Y. T.; Olivo, M. J. Biophotonics 2014, 7, 956-965.

257. Dark to light! A new strategy for large Stokes shift dyes: coupling of a dark donor with tunable high quantum yield acceptors, Su, D. D.; Oh, J.; Lee, S. C.; Lim, J. M.; Sahu, S.; Yu, X.; Kim, D.*; Chang, Y. T.* Chem. Sci. 2014, 5, 4812-4818.

256. Chemical targeting of GAPDH moonlighting function in cancer cells reveals its role in tubulin regulation, Jung, D. W.; Kim, W. H.; Seo, S.; Oh, E.; Yim, S. H.; Ha, H. H.; Chang, Y. T.; Williams, D. R. Chem. Biol. 2014, 21, 1533-1545.

255. Investigating fluorescent dyes in fluorescence-assisted screening, Jee, J. E.; Lim, J.; Hyun, H.; Oon, J.; Ong, Y. S.; Massif, C.; Chang, Y. T.; Choi, H. S.; Lee, S. S. Chem. Commun. 2014, 50, 15220-15223.

254. A molecular fluorescent probe for targeted visualization of temperature at the endoplasmic reticulum, Arai, S.; Lee, S. C.; Zhai, D.; Suzuki, M.; Chang, Y. T.* Sci. Rep. 2014, 4, 6701.

253. CDr10b inhibits the expression of cyclooxygenase-2 and inducible nitric oxide synthase induced by lipopolysaccharide, Gu, G. J.; Lim, S. J.; Ahn, S. I.; Lee, S. C.; Chang, Y. T.; Choi, T. H.; Kim, B. S.; Eom, Y. B.; Lee, N. K.; Youn, H. S. Eur. J. Pharmacol. 2014, 742, 42-46.

252. In Situ Investigation of Mammalian Inorganic Polyphosphate Localization Using Novel Selective Fluorescent Probes JC-D7 and JC-D8, Angelova, P. R.; Agrawalla, B. K.; Elustondo, P. A.; Gordon, J.; Shiba, T.; Abramov, A. Y.; Chang, Y. T.*; Pavlov, E. V.* ACS Chem Biol. 2014, 9, 2101-2110.

251. An artificial tongue fluorescent sensor array for identification and quantitation of various heavy metal ions, Xu, W.; Ren, C.; Teoh, C. L.; Peng, J.; Gadre, S. H.; Rhee, H. W.*; Lee, C. L. K.*; Chang, Y. T.* Anal. Chem. 2014, 86, 8763-8769.

250. Inhibition of tau aggregation by a rosamine derivative that blocks tau intermolecular disulfide cross-linking, Haque, M. M.; Kim, D.; Yu, Y. H.; Lim, S.; Kim, D. J.; Chang, Y. T.; Ha, H. H.; Kim, Y. K. Amyloid 2014, 21, 185-190.

249. Milk quality control: instant and quantitative milk fat determination with a BODIPY sensor-based fluorescence detector, Xu, W.; Bai, J.; Peng, J.; Samanta, A.; Divyanshu; Chang, Y. T.* Chem. Commun. 2014, 50, 10398-10401.

248. In vivo detection of macrophage recruitment in hind-limb ischemia using a targeted near-infrared fluorophore, Yoo, J. S.; Das, R. K.; Jow, Z. Y.; Chang, Y. T.* PLoS One 2014, 9, e103721.

247. A fluorescent probe for imaging symmetric and asymmetric cell division in neurospher formation, Yun, S. W.; Leong, C.; Bi, X.; Ha, H. H.; Yu, Y. H.; Tan, Y. L.; Narayanan, G.; Sankaran, S.; Kim, J. Y.; Hariharan, S.; Ahmed, S.*; Chang, Y. T.* Chem. Commun. 2014, 50, 7492-7494.

246. A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation, Kang, N. Y.; Park, S. J.; Ang, X. W.; Samanta, A.; Driessen, W. H.; Ntziachristos, V.; Vasquez, K. O.; Peterson, J. D.; Yun, S. W.*; Chang, Y. T.* Chem. Commun. 2014, 50, 6589-6591.

245. Live cells imaging using a turn-on FRET-based BODIPY probe for biothiols, Su, D.; Teoh, C. L.; Sahu, S.; Das, R. K.; Chang, Y. T.* Biomaterials 2014, 35, 6078-6085.

244. Biocompatible surface-enhanced Raman Scattering nanotags for in vivo cancer detection, Samanta, A.; Jana, S.; Chang, Y. T.* Nanomedicine 2014, 9, 523-535.

243. Multiplexing SERS nanotags for the imaging of differentiated mouse embryonic stem cells (mESC) and detection of teratoma in vivo, Samanta, A.; Das, R. K.; Park, S. J.; Maiti, K. K.; Chang, Y. T.* Am. J. Nucl. Med. Mol. Imaging 2014, 4, 114-124.

242. A Chemical Probe Selective for Human Pluripotent Stem Cells, Hirata, N.; Nakagawa, M.; Fujibayashi, Y.; Yamauchi, K.; Murata, A.; Minami, I.; Tomioka, M.; Kondo, T.; Kuo, T. F.; Endo, H.; Inoue, H.; Sato, S. I.; Ando, S.; Kawazoe, Y.; Aiba, K.; Nagata, K.; Kawase, E.; Chang, Y. T.; Suemori, H.; Eto, K.; Nakauchi, H.; Yamanaka, S.; Nakatsuji, N.; Ueda, K.; Uesugi1, M. Cell Rep. 2014, 6, 1165-1174.

241. Mechanistic elements and critical factors of cellular reprogramming revealed by stepwise global gene expression analyses, Park, S. J.; Yeo, H. C.; Kang, N Y.; Kim, H. J.; Lin, J.; Ha, H. H.; Vendrell, M.; Lee, J. S.; Chandran, Y.; Lee, D. Y.*; Yun, S. W.*; Chang, Y. T.* Stem Cell Res. 2014, 12, 730-741.

240. Diversity oriented fluorescence library approach (DOFLA) for live cell imaging probe development, Yun, S. W.; Kang, N. Y.; Park, S. J.; Ha, H. H.; Kim, Y. K.; Lee, J. S.; Chang, Y. T.* Acc. Chem. Res. 2014, 47, 1277-1286.

239. The role of “disaggregation” in optical probe development, Zhai, D.; Xu, W.; Zhang, L.; Chang, Y. T.* Chem. Soc. Rev. 2014, 43, 2402-2411.

238. Wavelength and shape dependent SERS study to develop ultrasensitive nanotags for imaging of cancer cells, Samanta, A.; Jana, S.; Das, R. K.; Chang, Y. T.* RSC Adv. 2014, 4, 12415-12421.

237. “Orange Alert”: A fluorescent detector for bisphenol A in water environments, Zhang, L.; Er, J. C.; Xu, W.; Qin, X.; Samanta, A.; Jana, S.; Lee, C. L. K.; Chang, Y. T.* Anal. Chim. Acta 2014, 815, 51-56.

236. meso-Ester and carboxylic acid substituted BODIPYs with far-red and near-infrared emission for bio-imaging applications, Ni, Y.; Zeng, L.; Kang, N. Y.; Huang, K. W.; Wang, L.; Zeng, Z.; Chang, Y. T.*; Wu, J.* Chem. Eur. J. 2014, 20, 2301-2310.

235. Actively targeted in vivo multiplex detection of intrinsic cancer biomarkers using biocompatible SERS nanotags, Dinish, U. S.; Balasundaram, G.; Chang, Y. T.; Olivo, M. Sci. Rep. 2014, 4, 4075.

234. Discovery of a structural-element specific G-quadruplex “Light-Up” probe, Zhang, L.; Er, J. C.; Ghosh, K. K.; Chung, W. J.; Yoo, J.; Xu, W.; Zhao, W.; Phan, A. T.; Chang, Y. T.* Sci. Rep. 2014, 4, 3776.

233. Development of a fluorescent sensor for an illicit date rape drug-GHB, Zhai, D.; Tan, Y. Q. E.; Xu, W.; Chang , Y. T.* Chem. Commun. 2014, 50, 2904-2906.

232. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens, Arora, P.; Baena, A.; Yu, K. O. A.; Saini, N. K.; Kharkwal, S. S.; Goldberg, M. F.; Kunnath-Velayudhan, S.; Carreño, L. J.; Venkataswamy, M. M.; Kim, J.; Lazar-Molnar, E.; Lauvau, G.; Chang, Y. T.; Liu, Z.; Bittman, R.; Al-Shamkhani, A.; Cox, L. R.; Jervis, P. J.; Veerapen, N.; Besra, G. S; Porcelli, S. Immunity, 2014, 40, 105-116.

231. A macrophage-specific fluorescent probe for intraoperative lymph node staging, Yoo, J. S.; Lee, S. C.; Jow, Z. Y.; Koh, P. Y. X.; Chang, Y. T.* Cancer Res. 2014, 74, 44-55.

230. Microglia specific fluorescent probe for live cell imaging, Leong, C.; Lee, S. C.; Ock, J.; See, P.; Park, S. J.; Ginhoux, F.; Yun, S. W.*; Chang, Y. T.* Chem. Commun. 2014, 50, 1089-1091.

229. Ratiometric fluorescent probes for hydrogen peroxide from a focused library, Lee, H. W.; Rhee, H. W.; Chang, Y. T.; Hong J. I. Chem. Eur. J. 2013, 19, 14791-14794.

228. Forward chemical genetic screening, Choi, H.; Kim, J. Y.; Chang Y. T.*; Nam, H. G.* Methods Mol. Biol. 2013, 1062, 393-404.

227. Neural stem cell isolation from the whole mouse brain using the novel FABP7-binding fluorescent dye, CDr3, Leong, C.; Zhai, D.; Kim, B.; Yun, S. W.*; Chang, Y. T.* Stem Cell Res. 2013, 11, 1314-1322.

226. Focused fluorescent probe library for metal cations and biological anions, Rhee, H. W.; Lee, S. W.; Lee, J. S.; Chang, Y. T.*; Hong, J. I.* ACS Comb. Sci. 2013, 15, 483-490.

225. A fluorescent dye cocktail for multiplex drug-site mapping on human serum albumin, Er, J. C.; Vendrell, M.; Tang, M. K.; Zhai, D.; Chang, Y. T.* ACS Comb. Sci. 2013, 15, 452-457.

224. Visualization and isolation of Langerhans islets by fluorescent probe PiY, Kang, N. Y.; Lee, S. C.; Park, S. J.; Ha, H. H.; Yun, S. W.; Kostromina, E.; Gustavsson, N.; Ali, Y.; Chandran, Y.; Chun, H. S.; Bae, M. A.; Ahn, J. H.; Han, W.; Radda, G. K.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2013, 52, 8557-8560.

223. Make Caffeine visible: a fluorescent caffeine “traffic light” detector, Xu, W.; Kim, T. H.; Zhai, D.; Er, J. C.; Zhang, L.; Kale, A. A.; Agrawalla, B. K.; Cho, Y. K.; Chang, Y. T.* Sci. Rep. 2013, 3, 2255.

222. A ratiometric fluorescent dye for the detection of glutathione in live cell and liver cancer tissue, Zhai, D.; Lee, S. C.; Yun, S. W.; Chang, Y. T.* Chem. Commun. 2013, 49, 7207-7209.

221. Development of a chalcone-triazine fusion library: combination of a fluorophore and biophore, Lee, S. C.; Zhai, D.; Chang, Y. T.* Tetrahedron Lett. 2013, 54, 2976-2979.

220. A unique small molecule inhibitor of enolase clarifies its role in fundamental biological processes, Jung, D. W.; Kim, W. H.; Park, S. H.; Lee, J.; Kim, J.; Su, D.; Ha, H. H.; Chang, Y. T.; Williams, D. R. ACS Chem. Biol. 2013, 8, 1271-1282.

219. The development of novel NIR tetraarylazadipyrromethene fluorescent dyes, Lee, S. C.; Zhai, D.; Mukherjee, P.; Chang, Y. T.* Materials 2013, 6, 1779-1788.

218. Development of fluorescent sensor for illicit date rape drug-GBL, Zhai, D.; Agrawalla, B. K.; Eng, E. S. F.; Lee, S. C.; Xu, W.; Chang, Y. T.* Chem. Commun. 2013, 49, 6170-6172.

217. Discovery of a Chondroitin 4-Sulfate Fluorescent Probe, Lee, S. C.; Zhai, D.; Chang, Y. T.* Supramol. Chem. 2013, 25, 41-45.

216. Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1, Hawley, T. S.; Riz, I.; Yang, W.; Wakabayashi, Y.; DePalma, L.; Chang, Y. T.; Peng, W.; Zhu, J.; Hawley, R. G. Am. J. Hematol. 2013, 88, 265-272.

215. MegaStokes BODIPY-Triazoles as Environmentally-Sensitive Turn-on Fluorescent Sensors, Er, J. C.; Tang, M. K.; Chia, C. G.; Liew, H.; Vendrell, M.*; Chang, Y. T.* Chem. Sci. 2013, 4, 2168-2176.

214. Surface Enhanced Raman Scattering in Cancer Detection and Imaging, Vendrell, M.; Maiti, K. K.; Dhaliwal, K.; Chang, Y. T. Trends Biotechnol. 2013, 31, 249-257.

213. Preparation and evaluation of BBB-permeable trehalose derivatives as potential therapeutic agents for Huntington’s disease, Im, J. K.; Kim, S. J.; Jeong, Y. H.; Kim, W.; Lee, D. H.; Lee, W. S.; Chang, Y. T.; Kim, K. T.; Chung, S. K. MedChemComm 2013, 4, 310-316.

212. Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors, Takahashi, H.; Takahashi, C.; Moreland, N. J.; Chang, Y. T.; Sawasaki, T.; Ryo, A.; Vasudevan, S. G.; Suzuki, Y.; Yamamoto, N. Antivir. Res. 2012, 96, 305-314.

211. Orally active desulfated low molecular weight heparin and deoxycholic acid conjugate, 6ODS-LHbD, suppresses neovascularization and bone destruction in arthritis, Hwang, S. R.; Seo, D. H.; Al-Hilal, T. A.; Jeon, O. C.; Kang, J. H.; Kim, S. H.; Kim, H. S.; Chang, Y. T.; Kang, Y. M.; Yang, V. C.; Byun, Y. J. Control. Release 2012, 163, 374-384.

210. High-performance graphene-titania platform for detection of phosphopeptides in cancer cells, Tang, L. A. L.; Wang, J.; Lim, T. K.; Bi, X.; Lee, W. C.; Lin, Q.; Chang, Y. T.; Lim, C. T.; Loh, K. P. Anal. Chem. 2012, 84, 6693-6700.

209. A fluorescent screening platform for the rapid evaluation of chemicals in cellular reprogramming, Vendrell, M.; Park, S. J.; Chandran, Y.; Lee, C. L. K.; Ha, H. H.; Kang, N. Y.; Yun, S. W.; Chang, Y. T.* Stem Cell Res. 2012, 9, 185-191.

208. Combinatorial strategies in fluorescent probe development, Vendrell, M.*; Zhai, D.; Er, J. C.; Chang, Y. T.* Chem. Rev. 2012, 112, 4391-4420.

207. Eastern Staining: A simple recombinant protein detection technology using a small peptide tag and its orthogonal fluorescent compound, Lee, J. J.; Kim, J. Y.; Zhai, D.; Yun, S. W.; Chang, Y. T.* Interdiscip. Bio Central 2012, 4, article no. 5, doi: 10.4051/ibc.2012.3.2.0005.

206. Combinatorial solid-phase synthesis of 4,6-diaryl and 4-aryl, 6-alkyl-1,3,5-triazines and their application to efficient biofuel production, Kim, J. Y. H.; Lee, J. W.; Lee, W. S.; Ha, H. H.; Vendrell, M.; Bork, J. T.; Lee, Y. S.*; Chang, Y. T.* ACS Comb. Sci. 2012, 14, 395-398.

205. Imaging Histamine in Live Basophils and Macrophages with a Fluorescent Mesoionic Acid Fluoride, Kielland, N.; Vendrell, M.; Lavilla, R.*; Chang, Y. T.* Chem. Commun. 2012, 48, 7401-7403.

204. Neural -stem cell specific fluorescent chemical probe binding to FABP7, Yun, S. W.; Leong, C. K. M; Zhai, D.; Tan, Y. L.; Lim, L.; Bi, X.; Lee, J. J.; Kim, H.; Kang, N. Y.; Ng, S. H.; Stanton, L. W.; Chang, Y. T.* Proc. Natl. Acad. Sci. USA 2012, 109, 10214-10217.

203. A novel zebrafish human tumor xenograft model validated for anti-cancer drug screening, Jung, D. W.; Oh, E. S.; Park, S. H.; Chang, Y. T.; Kim, C. H.; Choi, S. Y.; Williams, D. R. Mol. Biosyst. 2012, 8, 1930-1939.

202. Development of fluorescent Chalcone library and its application in the discovery of a mouse embryonic stem cell probe, Lee, S. C.; Kang, N. Y.; Park, S. J.; Yun, S. W.; Chandran, Y.; Chang, Y. T.* Chem. Commun. 2012, 48, 6681-6683.

201. Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic wnt signaling, Speese, S. D.; Ashley, J.; Jokhi, V.; Nunnari, J.; Barria, R.; Li, Y.; Ataman, B.; Koon, A.; Chang, Y. T.; Li, Q.; Moore, M. J.; Budnik, V. Cell 2012, 149, 832-846.

200. Multiplex Targeted in vivo Cancer Detection Using Sensitive Near-Infrared SERS Nanotags, Maiti, K. K.; Dinish, U. S.; Samanta, A.; Vendrell, M.; Soh, K. S.; Park, S. J.; Olivo, M.; Chang, Y. T.* Nano Today 2012, 7, 85-93.

199. Bioimaging Probes Development by DOFLA (Diversity Oriented Fluorescence Library Approach) for in vitro, in vivo and clinical applications, Yun, S. W.; Chang, Y. T.* in “Advances in Bio-Imaging: From Physics to Signal Understanding Issues”, pp 55-66, Eds. Loménie, Nicolas; Racoceanu, Daniel; Gouaillard, Alexandre, in State-of-the-Art and Challenges Series: Advances in Intelligent and Soft Computing, Vol. 120, Springer, 2012.

198. Diversity Oriented Fluorescence Library Approach for Stem Cell Probe Development, Yun, S. W.; Kang, N. Y.; Chang, Y. T.* in “Stem Cells and Cancer Stem Cells”, pp 7-14, Ed. Hayat, M. A., Therapeutic Applications in Disease and Injury, Vol. 3, Springer, 2012.

197. Solid-phase synthesis of dyes and their application as sensors and bioimaging probes, Vendrell, M.; Ha, H. H.; Lee, S. C.; Chang, Y. T.* in “Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications”, pp 427-440, Eds. Toy P. and Lam Y., Wiley-WCH, 2012.

196. Identification of cancer cell-line origins using fluorescence image-based phenomic screening, Lee, J. S.; Kim, Y. K.; Kim, H. J.; Hajar, S.; Tan, Y. L.; Kang, N. Y.; Ng, S. H.; Yoon, C. N.; Chang, Y. T.* PLoS One 2012, 7, e32096.

195. Synthesis of a novel BODIPY library and its application in the discovery of a fructose sensor, Zhai, D.; Lee, S. C.; Vendrell, M.; Leong, L. P. Chang, Y. T.* ACS Comb. Sci. 2012, 14, 81-84.

194. High content live cell imaging for the discovery of new antimalarial marine natural products, Cervantes, S.; Stout, P. E.; Prudhomme, J.; Engel, S.; Bruton, M.; Cervantes, M.; Carter, D.; Chang, Y. T.; Hay, M. E.; Aalbersberg, W.; Kubanek, J.; Le Roch, K. G. BMC Infect. Dis. 2012, 12:1.

193. Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy, Nath, S.; Spencer, V. A.; Han, J.; Chang, H.; Zhang, K.; Fontenay, G. V.; Anderson, C.; Hyman, J. M.; Nilsen-Hamilton, M.; Chang, Y. T.; Parvin, B. PLoS One 2012, 7, e28802.

192. Bioimaging of stem cells, live tissue and whole animals using Diversity Oriented Fluorescence Library Approach, Chang, Y. T.* in “The Primo Vascular System: Its Role in Cancer and Regeneration”, pp 285-289, Eds. K. S. Soh, K. A. Kang, and D. K. Harrison, Springer, 2012.

191. A triazine compound S06 inhibits pro-invasive crosstalk between carcinoma cells and stromal fibroblasts via binding to heat shock protein 90, Jung, D. W.; Kim, J.; Che, Z. M.; Oh, E. S.; Eom, S. H.; Im, S. H.; Ha, H. H.; Chang, Y. T.; Williams, D. R.; Kim, J. Chem. Biol. 2011, 18, 1581-1590.

190. Intracellular glutathione detection using MnO2-nanosheet modified upconversion nanoparticles, Deng, R; Xie, X.; Vendrell, M.; Chang, Y. T.; Liu, X. J. Am. Chem. Soc. 2011, 133, 20168-20171.

189. Diversity-oriented optical imaging probe development, Lee, J. S.; Vendrell, M.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2011, 15, 760-767.

188. Styryl-based and Tricyclic Compounds as Potential Anti-Prion Agents, Chung, E.; Prelli, F.; Dealler, S.; Lee, W. S.; Chang, Y. T.; Wisniewski, T. PLoS One 2011, 6, e24844.

187. Development of High Affinity Inhibitor of Prostaglandin Transporter PGT, Chi, Y; Min, J.; Jasmin, J. F.; Lisanti, M. P.; Chang, Y. T.; Schuster, V. L. J. Pharmacol. Exp. Ther. 2011, 339, 633-641.

186. Solid phase synthesis of ultra-photostable cyanine NIR dye library, Da, R. K.; Samanta, A.; Ha, H. H.; Chang, Y. T.* RSC Adv. 2011, 1, 573-575.

185. Combinatorial synthesis of galactosyl-1,3,5-triazines as novel nucleoside analogs, Wang, S.; Chang, Y. T.* Org. Biomol. Chem. 2011, 9, 6924-6926.

184. Solid-Phase Synthesis of BODIPY Dyes and Development of an Immunoglobulin Fluorescent Sensor, Vendrell, M.; Krishna, G. G.; Ghosh, K. K.; Zhai, D.; Lee, J. S.; Zhu, Q.; Yau, Y. H.; Shochat, S. G.; Kim, H. R.; Chung, J.; Chang, Y. T.* Chem. Commun. 2011, 47, 8424-8426.

183. Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain, Kim, Y. K.; Lee, J. K.; Lee, J. S.; Yoon, C. N.; Chang, Y. T.* Mol. Biosyst. 2011, 7, 2375-2378.

182. Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging, Lee, J. H.; So, J. H.; Jeon, J. H.; Choi, E. B.; Lee, U. R.; Chang, Y. T.; Kim, C. H.; Bae, M. A.; Ahn, J. H. Chem. Commun. 2011, 47, 7500-7502.

181. Synthesis and Characterization of a Cell-permeable Near-Infrared Fluorescent Deoxyglucose Analogue for Cancer Cell Imaging, Vendrell, M.; Samanta, A.; Yun, S. W.; Chang, Y. T.* Org. Biomol. Chem. 2011, 9, 4760-4762.

180. Ultrasensitive Near-Infrared Raman Reporters for SERS-based in vivo Cancer Detection, Samanta, A.; Maiti, K. K.; Soh, K. S.; Liao, X.; Vendrell, M.; Dinish, U. S.; Yun, S. W.; Bhuvaneswari, R.; Kim, H.; Rautela, S.; Chung, J.; Olivo, M.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2011, 50, 6089-6092.

179. Solid phase combinatorial synthesis of xanthone library using click chemistry and its application to embryonic stem cell probe, Ghosh, K. K; Ha, H. H.; Kang, N. Y.; Chandran, Y.; Chang, Y. T.* Chem. Commun. 2011, 47, 7488-7490.

178. Development of Intravascular Contrast Agents for MRI Using Gadolinium Chelates, Kittigowittana, K.; Yang, C. T.; Cheah, W. C.; Chuang, K. H.; Tuang, C. Y.; Chang, Y. T.; Golay, X.; Bates, R. W. ChemMedChem 2011, 781-787.

177. Diversity-driven chemical probe development for biomolecules: beyond hypothesis-driven approach, Kang, N. Y.; Ha, H. H.; Yun, S. W.; Yu, Y. H.; Chang, Y. T.* Chem. Soc. Rev. 2011, 40, 3613-3626.

176. Embryonic and induced pluripotent stem cell staining and sorting using live cell fluorescence imaging probe CDy1, Kang, N. Y.; Yun, S. W.; Ha, H. H.; Park, S. J.; Chang, Y. T.* Nat. Protoc. 2011, 6, 1044-1052.

175. Recapture of GFP Chromophore Fluorescence in a Protein Host, Baldridge, A.; Feng, S.; Chang, Y. T.; Tolbert, L. ACS Comb. Sci. 2011, 13, 214-217.

174. A Photostable Near-Infrared Protein Labeling Dye for in vivo Imaging, Samanta, A.;  Vendrell, M.; Yun, S. W.; Guan, Z.; Xu, Q. H.; Chang, Y. T.* Chem. Asian J. 2011, 6, 1353-1357.

173. A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids, Arora, Pooja; Venkataswamy, Manjunatha; Baena, Andres; Bricard, Gabriel; Li, Qian; Veerapen, N.; Ndonye, R.; Park, J. J.; Lee, J. H.; Seo, K. C.; Howell, A.; Chang, Y. T.; Illarionov, P.; Besra, G.; Chung, S. K.; Porcelli, S. J. Am. Chem. Soc. 2011, 133, 5198-5201.

172. Combinatorial Solid-Phase Synthesis of 6-aryl-1,3,5-triazines via Suzuki Coupling, Lee, J. W.; Ha, H. H.; Vendrell, M.; Bork, J. T.; Chang, Y. T.* Aust. J. Chem. 2011, 64, 540-544.

171. Bodipy-diacrylate Imaging Probes for Targeted Proteins inside Live cells, Lee, J. J; Lee, S. C.; Zhai, D.; Ahn, Y. H.; Yeo, H. Y.; Tan, Y. L.; Chang, Y. T.* Chem. Commun. 2011, 47, 4508-4510.

170. A colorimetric pH indicators and boronic acids ensemble array for quantitative sugar analysis, Ghosh, K. K.; Yap, E.; Kim, H. J.; Lee, J. S.; Chang, Y. T.* Chem. Commun. 2011, 47, 4001-4003.

169. Binding of fluorophores to proteins depends on the cellular environment, Kim, Y. K.; Lee, J. S.; Bi, X.; Ha, H. H.; Ng, S. H.; Ahn, Y. H.; Lee, J. J.; Wagner, B. K.; Clemons, P. A.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2011, 50, 2761-2763.

168. Fluorescent labelling of membrane proteins on the surface of living cells by a self-catalytic glutathione S-transferase omega 1 tag, Lee, J. J.; Son, J.; Ha, H. H.; Chang, Y. T.* Mol. Biosyst. 2011, 7, 1270-1276.

167. Target Identification: A Challenging Step in Forward Chemical Genetics, Das, R. K.; Samanta, A.; Ghosh, K.; Zhai, D.; Xu, W.; Su, D.; Leong, C.; Chang, Y. T.* Interdiscip. Bio Central 2011, 3, article no. 3, doi: 10.4051/ibc.2011.3.1.0003.

166. Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters, Maiti, K. K.; Samanta, A.; Vendrell, M.; Soh, K. S.; Olivo, M.; Chang, Y. T.* Chem. Commun. 2011, 47, 3514-3516.

165. Fluorescence response profiling for small molecule sensors utilizing the green fluorescent protein chromophore and its derivatives, Lee, J. S.; Baldridge, A.; Feng, S.; Yang, S. Q.; Kim, Y. K.; Tolbert, L. M.; Chang, Y. T.* ACS Comb. Sci. 2011, 13, 32-38.

164. Combinatorial search of sensors, Vendrell, M.; Feng, S.; Chang, Y. T.* in “Chemosensors: Principles, Strategies and Application”, pp 87-106, Ed. B. Wang and E. V. Anslyn, John Wiley and Sons, 2011.

163. Novel use of fluorescent glucose analogues to identify a new class of triazine-based insulin mimetics possessing useful secondary effects, Jung, D. W.; Ha, H. H.; Zheng, X.; Chang, Y. T.; Williams, D. R. Mol. Biosyst. 2011, 7, 346-358.

162. Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library, Lee, J. S.; Kim, H. K.; Feng S.; Vendrell, M.; Chang, Y. T.* Chem. Commun. 2011, 47, 2339-2341.

161. Quantitative structure-fluorescence property relationship analysis of a large BODIPY library, Schueller, A.; Goh, G. B.; Kim, H.; Lee, J. S.; Chang, Y. T.* Mol. Inf. 2010, 29, 717-729.

160. a-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents, Bricard, G.; Venkataswamy, M. M.; Yu, K. O. A.; Im, J. S.; Ndonye, R. M.; Howell, A. R.; Veerapen, N.; Illarionov, P. A.; Besra, G. S.; Li, Q.; Chang, Y. T.; Porcelli, S. A. PLoS One 2010, 5, e14374.

159. Development of photostable near-IR cyanine dyes, Samanta, A.; Vendrell, M.; Das, R.;  Chang, Y. T.* Chem. Commun. 2010, 46, 7406-7408.

158. Development of biocompatible SERS nanotag with increased stability by chemisorptions of reporter molecule for in vivo cancer detection, Maiti, K. K.; Dinish, U. S.; Fu, C. Y.; Lee, J. J.; Soh, K. S.; Yun, S. W.; Bhuvanaeswari, R.; Olivo, M.*; Chang, Y. T.* Biosens. Bioelectron., 2010, 26, 398-403.

157. A fluorescent rosamine compound selectively stains pluripotent stem cells, Im, C. N.; Kang, N. Y.; Ha, H. H.; Bi, X.; Lee, J. J.; Park, S. J.; Lee, S. Y.; Vendrell, M.; Kim, Y. K.; Lee, J. S.; Li, J.; Ahn, Y. H.; Feng, B.; Ng, H. H.; Yun, S. W.*; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2010, 49, 7497-7500. Highlighted at “Fluorescence method detects stem cells, C&En News, 2010 (September 20), 88 (38), p 25”

156. Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques, Hong, M. C.; Kim, Y. K.; Choi, J. Y.; Yang, S. Q.; Rhee, H.; Ryu, Y. H.; Choi, T. H.; Cheon, G. J; An, G. I.; Kim, H. Y.; Kim, Y.; Kim, D. J.; Lee, J. S.; Chang, Y. T.*; Lee, K. C.* Bioorg. Med. Chem. 2010, 18, 7724-7730.

155. Imaging metabolic syndrome, Han, W. P.; Chuang, K. H.; Chang, Y. T.; Olivo, M.; Velan, S. S.; Bhakoo, K.; Townsend, D.; Radda, G. K. EMBO Mol. Med. 2010, 2, 196-210.

154. Anti-amyloidogenic effect of AA3E2 attenuates beta-amyloid induced toxicity in SK-N-MC cells, Shaykhalishahi, H.; Taghizadeh, M.; Yazdanparast, R.; Chang, Y. T. Chem. Biol. Interact. 2010, 186, 16-23.

153. A chemical screen identifies novel compounds that overcome glial-mediated inhibition of neuronal regeneration, Usher, L.; Johnstone, A.; Erturk, A.; Hu, Y.; Strikis, D.; Wanner, I.; Moorman, S.; Lee, J. W.; Min, J.; Ha, H. H.; Duan, Y.; Hoffman, S.; Goldberg, J.; Bradke, F.; Chang, Y. T.; Lemmon, V.; Bixby, J. J. Neurosci. 2010, 30, 4693-4706.

152. Mitochondrial Affinity of Guanidine-rich Molecular Transporters Built on myo– and scyllo-Inositol Scaffolds: Stereochemistry Dependency, Ghosh, S. C.; Kim, B.; Im, J.; Lee, W. S., Im, C, N.; Chang, Y. T.; Kim, W.; Kim, K. T.; Chung, S. K. Bull. Korean Chem. Soc. 2010, 31, 3623-3631.

151. Diversity-oriented Fluorescence Library Approaches for Probe Discovery and Development, Vendrell, M.; Lee, J. S.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2010, 14, 383-389.

150. Discovery of Novel Zebrafish Neural Tracers by Organism-based Screening of Rosamine Library, Li, J.; Ha, H. H.; Guo, L.; Coomber, D.; Chang, Y. T.* Chem. Commun. 2010, 46, 2932-2934.

149. Isozyme-Specific Fluorescent Inhibitor of Glutathione S-Transferase Omega1­, Son, J. H.; Lee, J. J.; Lee, J. S.; Schuller, A.; Chang, Y. T.* ACS Chem. Biol. 2010, 5, 449-453.

148. Control of muscle differentiation by a mitochondria-targeted fluorophore, Kim, Y. K.; Ha, H. H.; Lee, J. S.; Bi, X. Z.; Ahn, Y. H.; Hajar, S.; Lee, J. J.; Chang, Y. T.* J. Am. Chem. Soc. 2010, 132, 576-579.

147. Combinatorial Synthesis of Triphenylmethine Library and Their Application in the Development of Surface Enhanced Raman Scattering (SERS) Probes, Cho, S. J.; Ahn, Y. H.; Maiti, K. K.; Dinish, U. S.; Fu, C. Y.; Thoniyot, P.; Olivo, M.; Chang, Y. T.* Chem. Commun. 2010, 46, 722-724.

146. Discovery of a Green DNA Probe for Live-Cell Imaging, Feng, S.; Kim, Y. K.; Yang, Q.; Chang, Y. T.* Chem. Commun. 2010, 46, 436-438.

145. Forward chemical genetics, Chang, Y. T.* in “Wiley Encyclopedia of Chemical Biology”, vol 2, pp94-111, Ed. Tadhq P. Beqley, Hoboken, N.J: John Wiley & Sons, 2009.

144. Functional profiling, identification and inhibition of plasmepsins in intraerythrocytic malaria parasites, Liu, K.; Shi, H.; Xiao, H.; Chong, A. G. L.; Bi, X.; Chang, Y. T.; Tan, K. Yada, R. Y.; Yao, S. Q. Angew. Chem., Int. Ed. Engl. 2009, 48, 8293-8297.

143. Inhibition of H2O2-induced neuroblastoma cell cytotoxicity by a triazine derivative, AA3E2, Shaykhalishahi, H.; Yazdanparast, R.; Ha, H. H.; Chang, Y. T. Eur. J. Pharmacol. 2009, 622, 1-6.

142. Synthesis and cellular uptake properties of guanidine-containing molecular transporters built on sucrose scaffold, Lee, W. S.; Im, C. N.; Teng, Q. Y.; Chang, Y. T.; Kim, D. C.; Kim, K. T.; Chung, S. K. Mol. Biosyst. 2009, 5, 822-825.

141. Synthesis of a bodipy library and its application to the development of live cell glucagon imaging probe, Lee, J. S.; Kang, N. Y.; Kim, Y. K.; Samanta, A.; Feng, S.; Kim, H. K.; Vendrell, M.; Park, J. H.; Chang, Y. T.* J. Am. Chem. Soc. 2009, 131, 10077-10082. Highlighted at JACS Select #10: Supramolecular and Chemical Cascade Approaches to Molecular Sensing.

140. Colorimetric sensor array for qualitative water anslysis, Chan, S. A.; Lee, J. S.; Chang Y. T.* Aust. J. Chem. 2009, 62, 1040-1046.

139. Novel orthogonal synthesis of tagged combinatorial triazine library via Grignard reaction, Lee, J. W.; Bork, J. T. Ha, H. H.; Samanta, A.; Chang, Y. T.* Aust. J. Chem. 2009, 62, 1000-1006.

138. Diversity oriented fluorescence library approach for novel sensor development, Wang, S.; Chang, Y. T.* in “Combinatorial methods for chemical and biological sensors”, pp 419-440, Eds. R. A. Potyrailo and V. M. Mirsky, Springer: New York, 2009.

137. Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation, Im, J. S.; Arora, P.; Bricard, G.; Molano, A.; Baine, I.; Jerud, E. S.; Goldberg, M. F.; Yu, K. O. A.; Howell, A. R.; Chang, Y. T.; Illarionov, P. A.; Besra, G. S.; Porcelli, S. A. Immunity, 2009, 30, 888-898.

136. High-content live cell imaging with RNA probes: advancements in high throughput antimalarial drug discovery, Cervantes, S.; Prudhomme, J.; Carter, D.; Krishna, G. G.; Li, Q.; Chang, Y. T., Le Roch, K. G. BMC Cell Biol. 2009, 10, 45.

135. Diversity-Oriented Fluorescence Library Approach for Discovery of Sensors and Probe, Lee, J. S.; Kim, Y. K.; Vendrell, M.; Chang, Y. T.* Mol. Biosyst. 2009, 5, 411-421.

134. Machine vision-assisted analysis of structure-localization relationships in a combinatorial library of prospective bioimaging probes, Shedden, K.; Li, Q.; Liu F.; Chang, Y. T.; Rosania, G. Cytometry A 2009, 75, 482-493.

133. Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility, Lee, L. L.; Ha, H.; Chang, Y. T.; DeLisa, M. P. Protein Sci. 2009, 18, 277-286.

132. Evaluation of synthetic sphingolipid analogs as ligands for peroxisome proliferators-activated receptors, Tsuji, K.; Satoh, S.; Mitsutake, S.; Murakami, I.; Park, J. J.; Li, Q.; Chang, Y. T.; Chung, S. K.; Igarashi, Y. Bioorg. Med. Chem. Lett. 2009, 19, 1643-1646.

131. Tagged library for chemical genetics, Chang, Y. T.* in Austin, D. (ed.), Chemical Biology: The role of Chemistry in our fundamental understanding of Biology, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://www.hstalks.com/?t=BL0331293-Chang), 2008.

130. Diversity oriented fluorescence library approach (DOFLA) to the discovery of chymotrypsin sensor, Wang, S.; Kim, Y. K.; Chang, Y. T.* J. Comb. Chem. 2008, 10, 460-465.

129. A selective human serum albumin sensor from the screening of a fluorescent rosamine library, Ahn, Y. H.; Lee, J. S.; Chang, Y. T.* J. Comb. Chem. 2008, 10, 376-380.

128. Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents, Zhou, C.; Min, J.; Liu, Z.; Young, A.; Deshazer, H.; Gao, T.; Chang, Y. T.; Kallenbach, N. R. Bioorg. Med. Chem. Lett. 2008, 18, 1308-1311.

127. Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening, Wagner, B. K.; Carrinski, H. A.; Ahn, Y. H.; Kim, Y. K.; Gilbert, T. J.; Fomina, D. A.; Schreiber, S. L.; Chang, Y. T.; Clemons, P. A. J. Am. Chem. Soc. 2008, 130, 4208-4209.

126. Discovery of heparin chemosensors through diversity oriented fluorescence library approach, Wang, S.; Chang, Y. T.* Chem. Commun. 2008, 1173-1175. Highlighted at “Blood sensor for safer surgery, Chemical Biology (RSC), 2008 (January 10)”

125. Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library, Park, J. J.; Li, Q.; Diaz, K.; Chang, Y. T.; Chung, S. K. Bioorg. Chem. 2008, 36, 220-228.

124. Synthesis and anticancer activity studies of cyclopamine derivatives, Zhang, J.; Garrossian, M.; Gardner, D.; Garrossian, A.; Chang, Y. T.; Kim, Y. K.; Chang, C. W. T. Bioorg. Med. Chem. Lett. 2008, 18, 1359-1363.

123. 중심학문으로서의 화학: 생물화학, Chang, Y. T.* 화학세계 2007, 24-31.

122. Enhancing effects of ceramide derivatives on 1,25-dihydroxyvitamin D(3)-induced differentiation of human HL-60 leukemia cells, Kim, D. S.; Kim, S. H.; Song, J. H.; Chang, Y. T.; Hwang, S. Y.; Kim, T. S. Life Sci. 2007, 81, 1638-1644.

121. Investigations of the molecular mechanism of metal-induced abeta (1-40) amyloidogenesis, Lim, K. H.; Kim, Y. K.; Chang, Y. T. Biochemistry 2007, 46, 13523-12532.

120. Rapid identification of immunostimulatory a-galactosylceramides using synthetic combinatorial libraries, Li, Q.; Ndonye, R. M.; Illarionov, P. A.; Yu, K. O. A.; Jerud, E. S.; Diaz, K.; Bricard, G.; Porcelli, S. A.; Besra, G. S.; Chang, Y. T.; Howell, A. R. J. Comb. Chem. 2007, 9, 1084-1093.

119. Combinatorial dapoxyl dye library and its application to site selective probe for human serum albumin, Min, J.; Lee, J. W.; Ahn, Y. H.; Chang, Y. T.* J. Comb. Chem. 2007, 9, 1079-1083.

118. Counterion free colorimetic metal cation sensor array, Lee, J. S.; Lee, J. W.; Chang, Y. T.* J. Comb. Chem. 2007, 9, 926-928.

117. Styryl-based compounds as potential in vivo imaging agents for b-amyloid plaques, Li, Q.; Min, J.; Ahn, Y. H.; Namm, J.; Kim, E. M.; Lui, R.; Kim, H. Y.; Ji, Y.; Wu, H.; Wisniewski, T.; Chang, Y. T.* ChemBioChem 2007, 8, 1679-1687.

116. Tagged small molecule library approach for facilitated chemical genetics, Ahn, Y. H.; Chang, Y. T.* Acc. Chem. Res. 2007, 40, 1025-1033.

115. Tagged library approach facilitates forward chemical genetics, Kim, Y. K.; Chang, Y. T.* Mol. Biosyst. 2007, 3, 392-397.

114. Combinatorial rosamine library and application to in vivo glutathione probe, Ahn, Y. H.; Lee, J. S.; Chang, Y. T.* J. Am. Chem. Soc. 2007, 129, 4510-4511.

113. Understanding activity of small molecules in the genomic context (Highlight article), Lee, J. S.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2007, 46, 3616-3618.

112. Small-molecule switch for zebrafish gene expression (News and Views), Chang, Y. T.*, Nat. Chem. Biol. 2007, 3, 135-136.

111. Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part II. Integrase inhibition, Lee-Huang, S.; Huang, P. L.; Zhang, D.; Lee, J. W.; Bao, J.; Sun, Y.; Chang, Y. T.; Zhang, J.; Huang, P. L. Biochem. Biophys. Res. Commun. 2007, 354, 879-884.

110. Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition, Lee-Huang, S.; Huang, P. L.; Zhang, D.; Lee, J. W.; Bao, J.; Sun, Y.; Chang, Y. T.; Zhang, J.; Huang, P. L. Biochem. Biophys. Res. Commun. 2007, 354, 872-878.

109. Forward chemical genetic approach identifies new role for GAPDH in insulin signaling, Min, J. K.; Kim, Y. K.; Cipriani, P. G.; Kang, M.; Khersonsky, S. M.; Walsh, D. P.; Lee, J. Y.; Niessen, S.; Yates, J. R.; Gunsalus, K.; Piano, F.; Chang, Y. T.* Nat. Chem. Biol. 2007, 3, 55-59. Highlighted at “New diabetes target, C&En News, 2006 (December 4), 84 (49), p 63” & “NYU, Scripps Finding offers New Path For Treatment of Diabetes, Medical News Today, 2006 (November 30)”

108. A protocol for preparing, characterizing and using three RNA-specific, live cell imaging probes: E36, E144 and F22, Li, Q.; Chang, Y. T.* Nat. Protoc. 2006, 1, 2922-2932.

107. Colorimetric identification of carbohydrates by a pH indicator/ pH change inducer ensemble, Lee, J. W.; Lee, J. S.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl., 2006, 45, 6485-6487. Highlighted at “Discriminating between carbohydrates, C&En News, 2006 (September 25), 84 (39), p 90”

106. Myoseverin is a potential angiogenesis inhibitor by inhibiting endothelial cell function and endothelial progenitor cell differentiation, Park, H. E.; Baek, S. H.; Min, J. K.; Chang, Y. T.; Kang, D. K.; Chang, S. I.; Joe, Y. A. DNA Cell Biol. 2006, 25, 514-522.

105. A high throughput screen for compounds that inhibit aggregation of the Alzheimer’s peptide, Kim, W.; Kim Y. K.; Min, J. K.; Kim, D. J.; Chang, Y. T.*; Hecht, M. H.* ACS Chem. Biol. 2006, 1, 461-469. Previewed at “From green bacteria to human dementia: a novel model for discovering amyloid assembly inhibitors, Gazit, E. Chem. Biol. 2006, 1, 417-419.

104. Combinatorial synthesis of benzimidazolium dyes and its diversity directed application toward GTP-selective fluorescent chemosensors, Wang, S.; Chang, Y. T.* J. Am. Chem. Soc. 2006, 128, 10380-10381.

103. RNA-selective, live cell imaging probes for studying nuclear structure and function., Li, Q., Kim, Y. K., Namm, J., Kulkarni, A., Rosania, G., Ahn, Y. H., Chang, Y. T.* Chem. Biol. 2006, 13, 615-623.  Previewed at “Styryl molecules light-up RNAs, Dirks, R. W.; Tnake, H. J. Chem. Biol. 2006, 13, 560-561.” Highlighted at “Styryl dyes image RNA in living cells, Borman, S. C&En News, 2006 (July 3), 84 (27), p30” & at “RNA dyes for life, Rothman, S. The Scientist, 2006, 20, 67” & at “Illuminating cellular RNA, Sheppard, T. L. Nat. Chem. Biol. 2006, 2, 405” & at “Live and let dye, Biotechniques 2006, 41, 231”

102. Visual artificial tongue for quantitative metal cation analysis by an off-the-shelf dye array, Lee, J. W.; Lee, J. S.; Kang, M.; Su, A. I.; Chang, Y. T.* Chem. Eur. J. 2006, 12, 5691-5696.

101. Chemical Genetics, Walsh, D. P.; Chang, Y. T.* Chem. Rev. 2006, 106, 2476-2530.

100. Inhibition of interleukin-4 production in activated T cells via the downregulation of AP-1/NF-AT activation by N-lauroyl-d-erythro-sphingosine and N-lauroyl-d-erythro-C(20)-sphingosine., Park, J.; Kim, S. H.; Li, Q.; Chang, Y. T. Kim, T. S. Biochem. Pharmacol., 2006, 71, 1229-1239.

99. Fce RI control of Ras via inositol (1,4,5) trisphosphate 3-kinase and inositol tetrakisphosphate, Stokes, A. J.; Shimoda, L. M.; Lee. J. W.; Chang, Y. T.; Turner, H. Cell Signal. 2006, 18, 640-651.

98. Identification of a new class of PGT inhibitors and characterization of their biological effects on PGE2 transport, Chi, Y.; Khersonsky, S. M.; Chang, Y. T.; Schuster, V. L. J. Pharmacol. Exp. Ther. 2006, 316, 1346-1350.

97. Identification of 12Cysb on tubulin as the binding site of tubulyzine, Kim, Y. J.; Sackett, D. L.; Schapira, M.; Walsh, D. P.; Min, J.; Pannell, L. K.; Chang, Y. T.* Bioorg. Med. Chem. 2006, 14, 1169-1675.

96. Triazine-based tyrosinase inhibitors identified by chemical genetic screening, Ni-Komatsu, L.; Leung, J. K.; Williams, D.; Min, J.; Khersonsky, S. M.; Chang, Y. T.; Orlow, S. J. Pigment Cell Res. 2005, 18, 447-453.

95. Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression, Harding, H. P.; Zhang, Y.; Khersonsky, S.; Marciniak, S.; Javitt, N.; Chang, Y. T.; Ron, D. Cell Metab. 2005, 2, 361-371.

94. A single cell analysis of myogenic dedifferentiation induced by small molecules, Duckmanton, A.; Kumar, A.; Chang, Y. T.; Brockes, J. P. Chem. Biol. 2005, 12, 1117-1126.

93. Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish, Jung, D. W.; Williams, D. Khersonsky, S. M.; Kang, T. W.; Heidary, N.; Chang, Y. T.; Orlow, S. J. Mol. Biosyst. 2005, 1, 85-92.

92. Bookreview for “Methods in Pharmacology and Toxicology: Optimization in Drug Discovery: In Vitro Methods” by Zhengyun Yan and Cary W. Caldwell, Chang, Y. T. ChemBioChem 2005, 6, 1127-1130.

91. Phytic Acid Synthesis and Vacuolar Accumulation in Suspension-Cultured Cells of Catharanthus roseus Induced by High Concentration of Inorganic Phosphate and Cations, Mitsuhashi, N.; Ohnishi, M.; Sekiguchi, Y.; Kwon, Y. U.; Chang, Y. T.; Chung, S. K.; Inoue, Y.; Reid, R. j.; Yagisawa, H.; Mimura, T. Plant Physiol. 2005, 138, 1607-1614.

90. Dissection of melanogenesis with small molecules identifies prohibitin as a regulator, Snyder, J. R.; Hall, A.; Ni-Komatsu, L.; Khersonsky, S. M.; Chang, Y. T.; Orlow, S. J. Chem. Biol. 2005, 12, 477-484. Highlighted at “Mitochondria give cells a tan, Rosania, G. R. Chem. Biol. 2005, 12, 412-413.”

89. Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of a-galactosylceramides, Yu, K. O. A.; Im, J. S.; Molano, A.; Dutronc, Y.; Illarionov, P. A.; Forestier, C.; Fujiwara, N.; Arias, I.; Miyake, S.; Yamamura, T.; Chang, Y. T.; Besra, G. S.; Porcelli, S. A.  Proc. Nat. Acad. Sci. U. S. A. 2005, 102, 3383-3388.

88. Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity, Lee-Huang, S.; Maiorov, V.; Huang, P. L.; Ng, A.; Lee, H. C.; Chang, Y. T.; Kallenbach, N.; Huang, P. L.; Chen, H. C. Biochemistry 2005, 44, 4648-4655.

87. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells, Park, J.; Li, Q.; Chang, Y. T.; Kim, T. S. Bioorg. Med. Chem. 2005, 13, 2589-2595.

86. Small molecule microarrays: recent advances and applications, Uttamchandani, M.; Walsh, P. D.; Yao, S. Q.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2005, 9, 4-13.

85. Solid phase synthesis of styryl dye library and its application to amyloid sensors, Li, Q.; Lee, J. S.; Ha, C.; Park, C. B.; Yang G.; Gan, W. B.; Chang, Y. T.* Angew. Chem., Int. Ed. Engl. 2004, 43, 6331-6335.

84. System dynamics of subcellular transport, Chen, V. Y.; Khersonsky, S. M.; Shedden, K.; Chang, Y. T.; Rosania, G. R. Mol. Pharm. 2004, 1, 414-425.

83. Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatases Schizosaccharomyces pombe synaptojanin and SHIP2, Chi, Y.; Zhou, B.; Wang, W. Q.; Chung, S. K.; Kwon, Y. U.; Ahn, Y. H.; Chang, Y. T. Tsujishita, Y.; Hurley, J. H.; Zhang, Z. Y. J. Biol. Chem. 2004, 279, 44987-44995.

82. Microarrays of Tagged Combinatorial Triazine Libraries in the Discovery of Small Molecule Ligands of Human IgG, Uttamchandani, M.; Walsh, D. P.; Khersonsky, S. M.; Huang, X.; Yao, S. Q.; Chang, Y. T.* J. Comb. Chem. 2004, 6, 862-868.

81. Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism, Williams, D.; Jung, D. W.; Khersonsky, S. M.; Heidary, N.; Chang, Y. T.; Orlow, S. J. Chem. Biol. 2004, 11, 1251-1259.

80. Recent Advances in Small Molecule Microarrays: Applications and Technology, Walsh, D. P.; Chang, Y. T.* Comb. Chem. High Throughput Screening 2004, 7, 557-564.

79. The combinatorial synthesis of purine, pyrimidine, and triazine-based libraries, Bork, J. T.; Lee, J. W.; Chang, Y. T.* QSAR Comb. Sci. 2004, 23, 245-260.

78. Strategies for facilitated forward chemical genetics, Khersonsky, S. M.; Chang, Y. T.* ChemBioChem 2004, 5, 903-908.

77. Forward chemical genetics: library scaffold design, Khersonsky, S. M.; Chang, Y. T.* Comb. Chem. High Throughput Screening 2004, 7, 645-652.

76. Dedifferentiation? What’s next? Kim, S.; Rosania, G. R.; Chang, Y. T.* Mol. Interv. 2004, 4, 83-85.

75. Tools for target identification and validation, Wang, S.; Sim, T.; Kim, Y. S.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2004, 8, 371-377.

74. Safety-Catch Approach to Orthogonal Synthesis of Triazine Library, Khersonsky, S. M.; Chang, Y. T.* J. Comb. Chem. 2004, 6, 474-477.

73. Molecular evolution using intramolecular acyl migration on myo-Inositol benzoates with thermodynamic and kinetic selectors, Ahn, Y. H.; Chang, Y. T.* Chem. Eur. J., 2004, 10, 3543-3547.

72. Molecular evolution on chiro-Inositol dibenzoate using intramolecular acyl migration and selection by phenyl boronic acid, Ahn, Y. H.; Chang, Y. T.* J. Comb. Chem. 2004, 6, 293-296.

71. Distinctive expression of Myf5 in relation to differentiation and plasticity of newt muscle cells, Imokawa, Y.; Gates, P. B. Chang, Y. T.; Simon, H. G., Brockes, J. P. Int. J. Dev. Biol. 2004, 48, 285-291.

70. Identification of a novel protein regulating microtubule stability through a chemical approach, Wignall, S. M.; Gray, N. S.; Chang, Y. T. Juarez, L.; Jacob, R. Burlingame, A.; Schultz, P. G.; Heald, R. Chem. Biol. 2004, 11, 135-246.

69. Tagged library approach to chemical genomics and proteomics, Mitsopoulos, G.; Walsh, D. P.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2004, 8, 26-32.

68. Chemoinformatic Analysis of a Supertargeted Combinatorial Library of Styryl Molecules, Shedden, K.; Brumer, J.; Chang, Y. T.; Rosania, G. R. J. Chem. Inf. Comput. Sci. 2003, 43, 2068-2080.

67. Facilitated forward chemical genetics using tagged triazine library and zebrafish embryo screening, Khersonsky, S. M.; Jung, D. W.; Kang, T. W.; Walsh, D. P.; Moon, H. S.; Jo, H.; Jacobson, E. M.; Shetty, V.; Neubert, T. A.; Chang, Y. T.* J. Am. Chem. Soc. 2003, 125, 11804-11805.

66. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment, Lee-Huang, S.; Zhang, L.; Huang, P. L.; Chang, Y. T.; Huang, P. L. Biochem. Biophys. Res. Commun. 2003, 307, 1029-1037.

65. Effects of Tubulyzines, Novel Microtubule-Binding Triazine Molecules, on Endothelial Progenitor Cell Differentiation, Park, H. E.; Lee, S. Y.; Ahn, H. Y.; Shin, J. C.; Chang, Y. T.; Joe, Y. A. J. Appl. Pharmacol. 2003, 11, 85-90.

64. Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles, Shedden, K.; Xie, X. T.; Chandaroy, P.; Chang, Y. T.; Rosania, G. R. Cancer Res. 2003, 63, 4331-4337.

63. Development of novel cell-permeable DNA sensitive dyes using combinatorial synthesis and cell based screening, Lee, J. W.; Jung, M.; Rosania, G. R.; Chang, Y. T.* ChemComm 2003, 1852-1853.

62. Palladium-catalyzed cross-coupling reaction of resin-bound chlorotriazines, Bork, J. T.; Lee, J. W.; Chang, Y. T.* Tetrahedron Lett. 2003, 44, 6141-6144.

61. Tubulyzine a novel trisubstituted triazine prevents the early cell death of transplanted myoblasts and improves myoblast transplantation success, El Fahime, E.; Bouchentouf, M.; Benabdallah, B. F.; Skuk, D.; Chang, Y. T.; Tremblay, J. P. Biochem. Cell Biol. 2003, 81, 81-90.

60. Understanding the effects of the polymer support on reaction rates and kinetics: knowledge toward efficient synthetic design, Walsh, D. P; Wu, D.; Chang, Y. T.* Curr. Opin. Chem. Biol. 2003, 7, 353-361.

59. Nitrophenol resins for facile amide and sulfonamide library synthesis, Lee, J. W.; Louie, Y. Q.; Walsh, D. P.; Chang, Y. T.* J. Comb. Chem. 2003, 5, 330-335.

58. Recent advances in glycomics and glycogenetics, Khersonsky, S. M.; Ho, C. M.; Garcia, M. F.; Chang, Y. T.* Curr. Top. Med. Chem. 2003, 3, 617-643 (with Preface: Chemical Biology and Chemical Genetics, Rosania, G. R. & Chang, Y. T. as Guest Editors).

57. Novel Orthogonal Strategy toward Solid Phase Synthesis of 1,3,5-Substituted Triazines, Bork, J.; Lee, J. W.; Khersonsky, S. M.; Moon, H. S.; Chang, Y. T. * Org. Lett. 2003, 5, 117-120.

56. Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold, Rosania, G. R.; Lee, J. W.; Ding, L.; Yoon, H. S.; Chang, Y. T.* J. Am. Chem. Soc. 2003, 125, 1130-1131.

55. Single Resin Bead Kinetics Using Real Time Fluorescence Measurements, Parikh, P. B.; Kim, Y. S.; Chang, Y. T.* Bull. Korean Chem. Soc. 2002, 23, 1509-1510.

54. A Novel Microtubule destabilizing Entity from Orthogonal Synthesis of Triazine Library and Zebrafish Embryo Screening, Moon, H. S.; Jacobson, E. M.; Khersonsky, S. M.; Luzung, M. R.; Walsh, D. P.; Xiong, W.; Lee, J. W.; Parikh, P. B.; Lam, J. C.; Kang, T. W.; Rosania, G. R.; Schier, A. F.; Chang, Y. T.* J. Am. Chem. Soc. 2002, 124, 11608-11609. Highlighted at “Paper alert, Hall, D. G. Curr. Opin. Chem. Biol. 2002, 6, 719.”

53. Purine based inhibitors of Inositol-1,4,5-trisphosphate-3-kinase, Chang, Y. T.*; Choi, G.; Bae, Y. S.; Burdett, M.; Moon, H. S.; Lee, J. W.; Gray, N. S.; Schultz, P. G.; Meijer, L.; Chung, S. K.; Choi, K. Y.; Suh, P. G.; Ryu, S. H. ChemBioChem 2002, 3, 897-901.

52. Divergent synthesis of all possible optically active regioisomers of myo-inositol tris- and tetrakisphosphates, Chung, S. K.; Kwon, Y. U.; Shin, J. H.; Chang, Y. T.; Lee, C. G.; Shin, B. G.; Kim, K. C.; Kim, M. J. J. Org. Chem. 2002, 67, 5626-2637.

51. Combinatorial Discovery of Novel Fluorescent Dyes Based on DapoxylTM, Zhu, Q.; Yoon, H. S.; Parikh, P. B.; Chang, Y. T.; Yao, S. Q. Tetrahedron Lett. 2002, 43, 5083-5086.

50. Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors, Perez, O. D.; Chang, Y. T.; Rosania, G.; Sutherlin, D.; Schultz, P. G. Chem. Biol. 2002, 9, 475-483 (with cover picture).

49. The synthesis and biological characterization of a ceramide library, Chang, Y. T.*; Choi, J.; Ding, S.; Prieschl, E. E.; Baumruker, T.; Lee, J. M.; Chung, S. K.; Schultz, P. G. J. Am. Chem. Soc. 2002, 124, 1856-1857.

48. Comparative resin kinetics using in situ fluorescence measurements, Walsh, D. P.; Pang, C.; Parikh, P. B.; Kim, Y. S.; Chang, Y. T.* J. Comb. Chem. 2002, 4, 204-208.

47. The identification and quantification of para-phenylenediamine in a temporary black henna tattoo, Brancaccio, R. R.; Brown, L. H.; Chang, Y. T.; Fogelman, J. P.; Mafong, E. A.; Cohen, D. E. Am. J. Contact Dermatitis 2002, 13, 15-18.

46. (±)-1,2;5,6-Di-O-isopropylidene-myo-inositol and (±)-1,2;4,5-di-O-isopropylidene-6-O-benzoyl-myo-inositol: a practical preparation of key intermediates for myo-inositol phosphates, Khersonsky, S. M.; Chang, Y. T.* Carbohydr. Res. 2002, 337, 75-78.

45. Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors, Chang, Y. T.*; Wignall, S. M.; Rosania, G. R.; Gray, N. S.; Hanson, S. R.; Su, A. I.; Merlie, Jr., J.; Moon, H. S.; Sangankar, S. B.; Perez, O.; Heald, R.; Schultz, P. G. J. Med. Chem. 2001, 44, 4497-4500.

44. Discovery of estrogen sulfotransferase inhibitors from a purine library screen, Verdugo, D. E.; Cancilla, M. T.; Ge, X.; Gray, N. S.; Chang, Y. T.; Schultz, P. G.; Negishi, M.; Leary, J. A.; Bertozzi, C. R. J. Med. Chem. 2001, 44, 2683-2686.

43. Inositol phospholipid pathway inhibitors and regulators, Chang, Y. T.*; Rosania, G. R.; Chung, S. K. Expert Opin. Ther. Pat. 2001, 11, 45-59.

42. Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilized inhibitors, Knockaert, M.; Gray, N.; Damiens, E.; Chang, Y. T.; Grellier, P.; Grant, K.; Fergusson, D.; Mottram, J.; Soete, M.; Dubremetz, J. F., Le Roch K.; Doerig, C.; Schultz, P. G.; Meijer, L. Chem. Biol. 2000, 7, 411-422.

41. Discovery of carbohydrate sulfotransferase inhibitors from a kinase-directed library, Armstrong, J. I.; Portley, A. R.; Chang, Y. T.; Nierengarten, D. M.; Cook, B. N.; Bowman, K. G.; Bishop, A.; Gray, N. S.; Shokat, K. M.; Schultz, P. G.; Bertozzi, C. R. Angew. Chem., Int. Ed. Engl., 2000, 39, 1303-1306.

40. A Novel DAST-induced Debenzylative Cycloetherization in D-1,2-O-Isopropylidene-3,4,5-tri-O-benzyl-myo-inositol, Chung, S. K.; Kwon, Y. U.; Ahn, Y. H.; Jeong, T. H.; Chang, Y. T. Bull. Korean Chem. Soc. 2000, 21, 274-276.

39. Myoseverin: a microtubule binding molecule with novel cellular effects, Rosania, G. R.; Chang, Y. T.; Perez, O.; Sutherlin, D.; Dong, H.; Lockhart, D. J.; Schultz, P. G. Nat. Biotechnol. 2000, 18, 304-308 (with cover picture): Highlighted at “Combinatorial chemistry gives cell biology some muscle, Hall, D. G. Nat. Biotechnol. 2000, 18, 261-262”.

38. Targeting hyperproliferative disorders with cyclin dependent kinase inhibitors, Rosania, G. R.; Chang, Y. T. Expert Opin. Ther. Pat. 2000, 10, 215-230.

37. Versatile fluorescence labeling method using activated esters on solid support, Chang, Y. T.; Schultz, P. G. Bioorg. Med. Chem. Lett. 1999, 9, 2479-2482.

36. Synthesis of All Possible Regioisomers of scyllo-Inositol Phosphate, Chung, S. K.; Kwon, Y. U.; Chang, Y. T.; Sohn, K. H.; Shin, J. H.; Park, K. H.; Hong, B. J.; Chung, I. H. Bioorg. Med. Chem. 1999, 7, 2577-2589.

35. Recombinant p42IP4, a brain-specific 42-kDa high-affinity Ins(1,3,4,5)P4
receptor protein, specifically interacts with lipid membranes containing Ptd-I(3,4,5)P3, Hanck, T.; Stricker, R.; Krishna, U. M.; Falck, J. R.; Chang, Y. T.; Chung, S. K.; Reiser, G. Eur. J. Biochem. 1999, 261, 577-584.

34. Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors, Chang, Y. T.; Gray, N.; Rosania, G. R.; Sutherlin, D. P.; Kwon, S.; Norman, T.; Sarohia, R.; Leost, M.; Meijer, L.; Schultz, P. G. Chem. Biol. 1999, 6, 361-375 (with cover picture).

33. A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts, Rosania, G. R.; Merlie, Jr., J.; Gray, N.; Chang, Y. T.; Schultz, P. G.; Heald, R. Proc. Natl. Acad. Sci. USA 1999, 96, 4797-4802.

32. An Efficient Synthesis of D-myo-Inositol 1,3,4,5-tetrakisphosphate, Chung, S. K.; Chang, Y. T.; Lee, E. J.; Kwon, Y. U. Kor. J. Med. Chem. 1998, 8, 18-21.

31. Syntheses of Two Enantiomeric Pairs of myo-Inositol-(1,2,4,5,6) and -(1,2,3,4,5)
pentakisphosphate, Chung, S. K.; Chang, Y. T.; Lee, E. J.; Shin, B. G.; Kwon, Y. U.; Kim, K. C.; Lee, D. H.; Kim, M. J. Bioorg. Med. Chem. Lett. 1998, 8, 1503-1506.

30. Syntheses of D- and L-myo-Inositol-1,2,4,5-tetrakisphosphate, the Stereoselectivity of I(1,4,5)P3 Receptor Recognition, Chung, S. K.; Shin, B. G.; Chang, Y. T.; Suh, B. C.; Kim, K. T. Bioorg. Med. Chem. Lett. 1998, 8, 659-662.

29. Syntheses of D-myo-Inositol-1,2,6-trisphosphate and -2,6-bisphosphate, Chung, S. K.; Yu, S. H.; Chang, Y. T. J. Carbohydr. Chem. 1998, 17, 385-390.

28. Synthesis of All Regioisomers of myo-Inositol Bisphosphates, Chung, S. K.; Chang, Y. T.; Kwon, Y. U. J. Carbohydr. Chem. 1998, 17, 369-384.

27. Molecular Probes for the Binding Site of Inositol 1,4,5-trisphosphate (IP3) 3-Kinase and Comparison with IP3 Receptor, Choi, G.; Chang, Y. T.; Chung, S. K.; Choi, K. Y. Kor. J. Med. Chem. 1997, 7, 106-114.

26. Selective Benzoylations of myo-Inositol Orthoformate and a Practical Synthesis of myo-Inositol-1,3,4,5-tetrakisphosphate, Chung, S. K.; Chang, Y. T.; Lee, J. W.; Ji, Y. K. Kor. J. Med. Chem. 1997, 7, 82-85.

25. Syntheses of myo-Inositol-1,2,3,5- and -2,4,5,6-tetrakisphosphates, Unusual Inhibitors of myo-Inositol-1,4,5-trisphosphate 3-Kinase, Chung, S. K.; Chang, Y. T.
Bioorg. Med. Chem. Lett. 1997, 7, 2715-2718.

24. Molecular Interactions of All Possible Regioisomers of Synthetic myo-Inositol Phosphates with myo-Inositol-1,4,5-trisphosphate 3-Kinase, Choi, G.; Chang, Y. T.; Chung, S. K.; Choi, K. Y. Bioorg. Med. Chem. Lett. 1997, 7, 2709-2714.

23. Microwave Enhanced Knoevenagel Condensation of Malonic Acid on Basic Alumina, Kwon, P. S.; Kim, Y. M.; Kang, C. J.; Kwon, T. W.; Chung, S. K.; Chang, Y. T. Syn. Commun. 1997, 27, 4091-4100.

22. Synthesis of D-Galactopyranosyl-1,2,6-trisphosphate as a Geometric Analogue of D-myo-Inositol 1,4,5-trisphosphate, Chung, S. K.; Kwon, Y. U.; Chang, Y. T. Kor. J. Med. Chem. 1997, 7, 63-68.

21. Solution Conformation and Kinetic Acidity of 1,2;4,5-Di-O-isopropylidene-myo-inositol, Chung, S. K.; Chang, Y. T. Kor. J. Med. Chem. 1997, 7, 15-18.

20. Microwave Enhanced Knoevenagel Condensation of Ethyl Cyanoacetate with
Aldehydes, Kim, S. Y.; Kwon, P. S.; Kwon, T. W.; Chung, S. K.; Chang, Y. T. Syn. Commun. 1997, 27, 533-541.

19. Theoretical Studies of Regioselectivity of myo-Inositol Derivatives: Importance of Solvent Dielectric Constants, Kim, K. S.; Cho, S. J.; Oh, K. S.; Son, J. S.; Kim, J.; Lee, J. Y.; Lee, S. J.; Lee, S.; Chang, Y. T.; Chung, S. K.; Ha, T. K.; Lee, B. S.; Lee, I. J. Phys. Chem. 1997, 101, 3776-3783.

18. Binding and Activity of the Nine Possible Regioisomers of myo-Inositol
Tetrakisphosphate at the Inositol 1,4,5-Trisphosphate Receptor, Burford, N. T.; Nahorski, S. R.; Chung, S. K.; Chang, Y. T.; Wilcox, R. A. Cell Calcium 1997, 21, 301-310.

17. Rapid Kinetic Measurements of 45Ca2+ Mobilization Reveal that Inositol
2,4,5-Trisphosphate is a Partial Agonist at Hepatic Inositol Trisphosphate Receptor, Marchant, J. S.; Chang, Y. T.; Chung, S. K.; Irvine, R. F.; Taylor, C. W. Biochem. J. 1997, 321, 573-576.

16. Determination of Specificity of a High Affinity Inositol-1,3,4,5-tetrakisphosphate Binding Site at a 42 kD Receptor Protein: Comparison of Affinities of All Regioisomers of Inositol Tris-, Tetrakis-, and Pentakisphosphate, Stricker, R.; Chang, Y. T.; Chung, S. K.; Reiser, G. Biochem. Biophys. Res. Commun. 1996, 228, 596-604.

15. Synthesis of myo-Inositol-1,2,3-trisphosphate by Selective Benzylation: the Iron Binding Motif of Phytic acid (IP6), Chung, S. K.; Chang, Y. T. Kor. J. Med. Chem. 1996, 6, 253-258.

14. Synthesis of All Possible Regioisomers of myo-Inositol Monophosphate, Chung, S. K.; Chang, Y. T. Kor. J. Med. Chem. 1996, 6, 162-165.

13. Crystal Structures of DL-1,4-Di-O-benzoyl-2,3-O-isopropylidene-myo-inositol and DL-1,4-Di-O-benzoyl-5,6-O-isopropylidene-myo-inositol: a Conformational Analysis, Chung, S. K.; Chang, Y. T.; Whang, D.; Kim, K. Carbohydr. Res. 1996, 295, 1-6.

12. Synthesis of All Possible Regioisomers of myo-Inositol Pentakisphosphate, Chung, S. K.; Chang, Y. T. Bioorg. Med. Chem. Lett. 1996, 6, 2039-2042.

11. Ab initio Conformational Study of 1,2,;4,5-Di-O-isopropylidene-myo-inositol, Lee, S. J.; Cho, S. J.; Oh, K. S.; Cui, C.; Ryu, Y.; Chang, Y. T.; Kim, K. S.; Chung, S. K. J.
Phys. Chem.
1996, 100, 10111-10115.

10. Synthesis and Iron Binding Studies of myo-Inositol-1,2,3-trisphosphate and
DL-myo-Inositol-1,2-bisphosphate, and Iron Binding Studies of All myo-Inositol-
tetrakisphosphates, Spiers, I. D.; Barker, C. J.; Chung, S. K.; Chang, Y. T.; Freeman, S.; Gardiner, J. M.; Hirst, P. H.; Lambert, P. A.; Michell, R. H.; Poyner, D. R.; Schwalbe, C. H.; Smith, A. W.; Solomons, K. R. H. Carbohydr. Res. 1996, 282, 81-99.

9. New Approach to the Synthetic Problems of myo-Inositol Phosphates and Their Biological Utilities, Chung, S. K.; Chang, Y. T.; Sohn, K. H. in “Medicinal Chemistry: Today and Tomorrow”, pp 63-68, Ed. M. Yamazaki, Blackwell Science, 1996.

8. A Divergent Approach toward Synthesis of myo-Inositol Phosphates: Acyl
Migration and Regioselectivity, Chung, S. K.; Chang, Y. T.; Ryu, Y. Pure Appl. Chem. 1996, 68, 931-935.

7. Practical Divergent Synthesis of All Possible Regioisomers of myo-Inositol Trisphosphates, Chung, S. K.; Chang, Y. T.; Sohn, K. H. J. Chem. Soc., Chem. Commun. 1996, 163-164.

6. Specificity of the Purified Inositol-1,3,4,5-tetrakisphosphate-binding Protein from Porcine Platelets, Cullen, P. J.; Chung, S. K.; Chang, Y. T.; Dawson, A. P.; Irvine,
R. F. FEBS Lett. 1995, 358, 240-242.

5. Base-catalyzed Acyl Migration in myo-Inositol Dibenzoates, Chung, S. K.; Chang, Y. T. J. Chem. Soc., Chem. Commun. 1995, 13-14.

4. Synthesis of All Possible Regioisomers of myo-Inositol Tetrakisphosphates, Chung, S. K.; Chang, Y. T. J. Chem. Soc., Chem. Commun. 1995, 11-12.

3. Synthesis of myo-Inositol-1,4,5-, 2,4,6-, and 1,3,5-trisphosphate, Chung, S. K.; Chang, Y. T.; Sohn, K. H. Kor. J. Med. Chem. 1994, 4, 57-65.

2. Crystal Structure of 1,2;4,5-Di-O-isopropylidene myo-Inositol and 1,2;5,6-Di-O-isopropylidene myo-Inositol: a Conformational Analysis, Chung, S. K.; Ryu, Y.; Chang, Y. T.; Whang, D.; Kim, K. Carbohydr. Res. 1994, 253, 13-18.

1. Synthesis of myo-Inositol-1,4,5-trisphosphate and myo-Inositol-1,4-bisphosphate, Chung, S. K.; Ryu, Y.; Chang, Y. T.; Moon, S. H. Kor. J. Med. Chem. 1992, 2, 33-44.